The benefits of
each increased ability level are completely unclear.
Not exact matches
«If we're to keep global temperatures from rising to dangerous
levels, we need to drastically reduce emissions and greatly
increase forests»
ability to absorb and store carbon.»
Actual results, including with respect to our targets and prospects, could differ materially due to a number of factors, including the risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in
increased inventory and reduced orders as we experience wide fluctuations in supply and demand; the risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our
ability to lower costs; the risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on additional capacity on a timely basis to meet customer demand; the risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix; risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters as consumers and businesses may defer purchases or payments, or default on payments; risks resulting from the concentration of our business among few customers, including the risk that customers may reduce or cancel orders or fail to honor purchase commitments; the risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the risk that retail customers may alter promotional pricing,
increase promotion of a competitor's products over our products or reduce their inventory
levels, all of which could negatively affect product demand; the risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the risk posed by managing an increasingly complex supply chain that has the
ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired; risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our
ability to complete development and commercialization of products under development, such as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products risks related to our multi-year warranty periods for LED lighting products; risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products; risks associated with ongoing litigation; and other factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.
Commuting has an effect on performance as it
increases anger and resentment at work, absenteeism, and has a negative impact on punctuality and the
ability to focus and perform at the same
level as other colleagues who live nearer to the place of work.»
The Fed for example fought a difficult battle with inflation in the 1970s, hiking interest rates to recession - provoking
levels and eventually winning a war of credibility over its
ability to rein in price
increases.
In particular, as disclosed in filings with the U.S. Securities and Exchange Commission, Amarin's
ability to effectively develop and commercialize Vascepa will depend in part on its
ability to continue to effectively finance its business, efforts of third parties, its
ability to create market demand for Vascepa through education, marketing and sales activities, to achieve
increased market acceptance of Vascepa, to receive adequate
levels of reimbursement from third - party payers, to develop and maintain a consistent source of commercial supply at a competitive price, to comply with legal and regulatory requirements in connection with the sale and promotion of Vascepa and to maintain patent protection for Vascepa.
These risks and uncertainties include: Gilead's
ability to achieve its anticipated full year 2018 financial results; Gilead's
ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may
increase the amount of discount required on Gilead's products; an
increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's
ability to initiate clinical trials in its currently anticipated timeframes; the
levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's
ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's
ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's
ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's
ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's
ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's
ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
The success of our ES segment is to a significant degree dependent on our
ability to retain our significant services clients and maintain or
increase the
level of revenues from these clients.
Our collaboration with MaRS will help us to serve social entrepreneurs at all stages to
increase their
ability to achieve positive social and environmental impact at a local and global
level.»
In anticipation of the tax bill's passage and of municipalities losing their
ability to refund bonds prior to maturity, there was a surge in supply of muni bonds in November and December, with new supply
increasing 29.3 % and 207 %, respectively, over prior - year
levels.
Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or
increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the
level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and
increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the
ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the
ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our
ability to borrow and could
increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future
increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy
levels at different times of the year; our
ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
Sustained economic growth is only possible if there is technical progress: the
ability to continually
increase output
levels with a fixed
level of inputs.
It is well - known for its
ability to assist in
increasing levels of dopamine and serotonin — neurotransmitters that control the brain's reward and pleasure centers, reduce stress and stabilize mood.
This rare little amino acid packs some pretty amazing health benefits and is well - known for its
ability to assist in
increasing levels of dopamine and serotonin.
Because of their
ability to
increase serotonin
levels, fish oils are a lovely mood food to include in your diet.
The Journal of Alternative and Complementary Medicine, goji berry benefits include
increased ratings for energy
levels, athletic performance, quality of sleep, ease of awakening,
ability to focus on activities, mental acuity, calmness, feelings of health, contentment, and happiness and significantly reduced fatigue and stress.
Higher
levels of general education have been found to
increase the
ability of individuals to obtain and understand the health - related information needed to develop health - promoting behaviours.
Maca powder is an adaptogenic root long - revered for its
ability to
increase energy
levels and relieve stress.
Our Bloomingdale facility is at the heart of our manufacturing and distribution network and strongly supports our
ability to achieve consistent
levels of product quality, efficacy, and safety, as well as our
ability to meet
increasing consumer demand.
If he can develop consistency in his
increased contact rate and
ability to draw walks, his other numbers should rise, also, maybe enough to produce at a major league
level, even if as a utility player.
Bilirubin
levels in the blood can be high because of higher production of it in a newborn, an
increased ability of the newborn intestine to absorb it, and a limited
ability of the newborn liver to handle large amounts of it.
As the birth of a new baby nears, a mother's oxytocin
level, known as the «love hormone» because of its
ability to create warm feelings of safety and attachment,
increases as part of the preparation for bringing a new life into the world and sustaining that life at her breast.
«The
ability to provide a treatment that can
increase stress resiliency at the cellular
level, and hopefully also the behavioral
level, would be a much welcomed addition to our antidepressant armamentarium,» says Gerard Sanacora, a professor of psychiatry at Yale University School of Medicine and director of the Yale Depression Research Program.
Back in 1985, Wise's colleagues Beverly Whipple and Barry Komisaruk, both at Rutgers, discovered that during self - stimulation and orgasm, women's
ability to withstand painful finger squeezing
increased by 75 per cent, and the
level of squeezing at which women noticed the pain more than doubled.
«This Agreement, in enhancing the implementation of the [2015 United Nations Framework Convention on Climate Change], including its objective, aims to strengthen the global response to the threat of climate change, in the context of sustainable development and efforts to eradicate poverty, including by: (a) Holding the
increase in the global average temperature to well below 2 °C above pre-industrial
levels and pursuing efforts to limit the temperature
increase to 1.5 °C above pre-industrial
levels, recognizing that this would significantly reduce the risks and impacts of climate change; (b)
Increasing the
ability to adapt to the adverse impacts of climate change and foster climate resilience and low greenhouse gas emissions development, in a manner that does not threaten food production; and (c) Making finance flows consistent with a pathway towards low greenhouse gas emissions and climate - resilient development.
By contrast, roasting at 302 F or above
increased the
levels of catechin and larger proanthocyanidins, which have a greater
ability to inhibit pancreas lipase.
The
ability of the oceans to take up carbon dioxide can not keep up with the rising
levels of greenhouse gases in the atmosphere, which means carbon dioxide and global temperatures will continue to
increase unless humans cut their carbon dioxide emissions.
Increasing the expression of one of the proteins, SIX3, in the insulin - producing cells isolated from younger donors enhanced their
ability to respond efficiently to rising glucose
levels.
Dancing joins athleticism, musical
ability and facial symmetry on a growing list of traits that
increase a man's attractiveness and are associated with prenatal testosterone
levels.
Sen would also ascertain
levels of burglary, robbery and assault, with the aim of discovering whether evidence exists for strict gun laws
increasing crime by reducing people's
abilities to protect themselves.
Understanding how this immune system is regulated at the appropriate
level of activity gives the researchers more ideas of points in the immune signaling pathway that could targeted to
increase the plant's baseline
ability to resist disease.
Dr Mohamed Elrayess, from ADLQ, said: «In this study we have shown that the impaired
ability of fat stem cells to store excess fat was partially due to
increased levels of the inflammatory marker interleukin - 6 in the blood.
Two - thirds experienced a deterioration in their body's
ability to regulate diabetes, with the number classed as having acute problems controlling blood sugar
levels increasing from 32 per cent to 41 per cent.
They found that by adding it to the high - fat diet, the compound would decrease the
level of obesity in the animals and would
increase their
ability to deal with
increased blood glucose
levels.
The genes
increased their egg - laying
ability but with the unfortunate side effect of boosting sexual attractiveness to a
level where males wouldn't leave them alone.
«
Increased carbon dioxide
levels in air restrict plants»
ability to absorb nutrients.»
Participants who exercised also showed an
increase in their overall attention
levels and
ability to focus.
Another way is to strengthen the immune system by raising the
levels of IL - 22 but we would rather find ways to
increase the immune system's
ability to kill the Borrelia bacteria.»
«These results suggest that continuing
increases in atmospheric CO2 associated with global climate change will
increase both the
level of Alternaria exposure and antigenicity [the
ability to produce an immune response] of spores that come in contact with the airways.»
Likewise, certain brain regions of these optogenetically stimulated, post-stroke mice showed
increased levels of proteins associated with heightened
ability of nerve cells to alter their structural features in response to experience — for example, practice and learning.
Reticulon 4 receptor (RTN4R): Lowered
levels of RTN4R can
increase plasticity in the adult brain in mice, improving recovery from brain injury and
increasing the
ability to learn new tasks.
While Viagra is more commonly known for its
ability to help with pulmonary hypertension and erectile dysfunction, Browning's teams also discovered that it
increases levels of GMP found in the blood.
We hypothesize that the mechanism of action of J147 is related to its
ability to
increase the
levels of BDNF and NGF, and studies are being conducted to identify its molecular target.
Thiol - reactive electrophilic compounds often
increase ROS
levels in cells, as a consequence of their
ability to deplete glutathione.
During periods of oxidative stress, as
levels of reactive electrophilic metabolites
increase, the
ability of Keap1 to target Nrf2 for ubiquitin - dependent degradation is disrupted, thereby
increasing Nrf2 protein
levels and its transport into the nucleus, resulting in transcription of antioxidant response genes [5], [6], [8], [10], [11].
Source: Lyman 2010 The reaction of the oceans to climate change are some of the most profound across the entire environment, including disruption of the ocean food chain through chemical changes caused by CO2, the
ability of the sea to absorb CO2 being limited by temperature
increases, (and the potential to expel sequestered CO2 back into the atmosphere as the water gets hotter), sea -
level rise due to thermal expansion, and the amount of water vapour in the atmosphere.
This makes strongman training superior to its more traditional counterpart because it allows you to get a higher
level of metabolic gains, muscle - building hormone
levels and
increased fat - burning
ability, but without the unpleasant muscle soreness associated with the latter.
Another fish oil benefit to bodybuilders and athletes is the
ability to keep hormone - producing glands active.This means higher
levels of testosterone in the blood, which eventually leads to
increased muscle mass.
Additionally,
increasing the testosterone
levels is beneficial for your libido and your mental
abilities, not to mention that it improves your sporting performances.
When you replace dietary fat with more carbs, as most women tend to do, your blood sugar and insulin
levels increase and harm your body's fat burning
ability.