Sentences with phrase «increased apoptotic»

The results showed a 70 percent increased apoptotic rate in liver cancer cells compared to normal cells.

Not exact matches

Evidence suggests that the resolution of infection and thus inflammation is prolonged due to reduced clearance of apoptotic cells and debris by macrophages.11 These age - associated alterations in innate immunity may contribute to increased systemic inflammation termed «inflamm - ageing» observed in aged tissues.10

Compared with the untreated group and the groups treated with single agents, the number of apoptotic tumor cells was increased following combined treatment (Figure 4D).

This effect on growth inhibition was not due to alterations in cell cycle (Supplemental Fig. 5) nor a significant increase in the apoptotic cell populations, suggesting that RIPK2 inhibition of proliferation is independent of cell cycle or apoptotic changes.

By examining this damage, it was found that the Bax / Bcl2 ratio, a parameter that is indicative of the apoptosis status [21], was increased in the testes of IVC - derived males, suggesting that there were a high number of apoptotic cells in that tissue, and this was confirmed by TUNEL assay.

Next, we found that the increase of p21Cip1 / WAF1 expression, which occurs upon LA exposure in a p53 - independent manner, is involved in the apoptotic effects prompted by LA in both breast and endometrial cancer cells.

A 70 - 90 % reduction in colony formation has been observed, as well as a remarkable increase in apoptotic cancer cells (cells that are programmed to die).

In addition, during puberty and into the third decade, oestrogen has an anabolic effect on the osteoblast and an apoptotic effect on the osteoclast, increasing bone mineral acquisition in axial and appendicular bone.