The investigators proposed that the abundance of large megakaryocytes contribute to the signal, since in T2 - weighted MR - images, increased water / proton content, as in
increased cellularity, yield high (bright) MR - signal intensity.
However, for the NOS group the reverse was seen, with overcrowding being associated with an
increased incidence of this type of HL, while deprivation seemed to have no effect on the incidence of the mixed
cellularity and lymphocyte - rich sub-types.