Sentences with phrase «increased disease markers»

Not exact matches

A new study of 635 children in Massachusetts found that a bigger waist size at age 3 increases the odds that a child will have a marker for liver damage and nonalcoholic fatty liver disease by age 8.

Individuals were classified as high risk for Alzheimer's if a DNA test identified the presence of a genetic marker — having one or both of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the risk of developing the disease.

Compared to eating earlier in the day, prolonged delayed eating can increase weight, insulin and cholesterol levels, and negatively affect fat metabolism, and hormonal markers implicated in heart disease, diabetes and other health problems, according to results from researchers at the Perelman School of Medicine at the University of Pennsylvania.

In mice, this form of lipodystrophy was also characterized by «whitening» of brown fat cells, a loss of white fat, and signs of metabolic syndrome, including insulin resistance, fat tissue inflammation, dyslipidemia (elevated cholesterol and fat), increased resting energy use, and increased markers of cardiovascular disease.

All had abnormalities of TP53 or ATM — two mutations associated with high - risk disease — and two patients had increasing BTK C481S clones, also a high - risk marker.

Indeed, low birth weight, a marker of impaired fetal development, is associated with increased everyday levels of inflammatory markers as well as greater risks of heart disease, diabetes, depression and schizophrenia in adults.

In the study, the children that developed severe disabilities or died from TBM had the highest levels of these biological markers, and the levels increased over time, suggesting that this information could be used to help predict disease outcome.

«We've got a marker for biological aging — telomere length — so we're studying whether we can relate it to the increased risk of getting some of these age - associated diseases.

Rats born of hypoxic pregnancy with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and molecular markers of disease, such as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.

Markers associated with increased susceptibility to infection, severity of disease and response to vaccine

Also consistent with increased disease severity, gp33 - immunized mice had an elevation of serum markers of HLH, including significantly elevated ferritin and a trend toward elevated sCD25 / IL -2 Ra (Fig. 1F).

«The observed increase in the ratio of cytotoxic CD4 T cells to CD4 helper T cells indicates that they are an important component of the protective immune response to viral infections and that their induction should be an important marker for successful vaccinations against certain viral diseases,» says postdoctoral researcher and first author Veena Patil, Ph.D. «But we really didn't know enough about their molecular profile and the mechanisms that drive their differentiation and maintenance.»

Three recent experimental studies focused on low consumption / exposure.949596 In one study, 29 smokers each consumed a single cigarette, immediately after which they had a significant decrease in blood vessel output power and significant increase in blood vessel ageing level and remaining blood volume 25 minutes later, as markers of atherosclerosis.94 In another study, human coronary artery endothelial cells were exposed to the smoke equivalent to one cigarette, which led to activation of oxidant stress sensing transcription factor NFR2 and up - regulation of cytochrome p450, considered to have a role in the development of heart disease.95 These effects were not seen when heart cells were exposed to the vapour from one e - cigarette.95 A study exposed adult mice to low intensity tobacco smoke (two cigarettes) for one to two months and found adverse histopathological effects on brain cells.96

Even further, studies on high - fat diets show that increased consumption of saturated fat has beneficial impacts on cardiovascular disease risk markers, including decreasing the level of triglycerides, fasting glucose, blood pressure, as well as increasing HDL cholesterol blood levels.

Doctors have speculated that folic acid may improve heart health, because people with B - vitamin deficiencies often have high blood levels of the amino acid homocysteine, a marker of inflammation that has been linked to an increased risk of heart disease.

Poor sleep also been associated with increases in the inflammatory markers often seen with autoimmune diseases.

One study of Belgian workers found that those who reported feeling they had little control of their work life had increased levels of markers of inflammation such as C - reactive protein and fibrinogen, which are linked to heart disease.

In another study of overweight adults, eating fermented full - fat dairy products — ie, cheese and yogurt — resulted in a greater reduction in inflammatory markers known to increase heart disease risk compared to low - fat versions of these dairy products (26).

Surprisingly, the researchers did not find increased levels of Alzheimer's markers when they looked specifically at people with obstructive sleep apnea, a breathing disorder that's a major disruptor of sleep and a risk factor for several other chronic diseases.

It can also work in conjunction with chromium to reduce LDL levels and increase HDL since inverse levels of each are markers for increased risk of heart disease.

[7] Flaxseed also lowers inflammatory markers related to increased risk for heart disease.

Excess testosterone also tends to negate the benefits of testosterone supplementation, which include better mood, increased energy, clearer thinking, increased muscle mass and improved heart disease and diabetes markers.

Much more impressive evidence also was published to show that the early stages of heart disease, atherosclerosis, and its predictive serum cholesterol marker, were increased much more by dietary protein than by dietary fat, especially the protein in animal - based foods.»

OCPs have been found to increase levels of LDL, Triglyceride, and C - reactive protein (CRP), a marker of inflammation and heart disease.

Telomere length is arguably the best marker of biological age, and shorter mean telomere length, usually measured in your white blood cells, is associated with increased risk of heart disease, obesity, cancer, stroke, dementia, and premature death (2).

«Given the high content of certain specific polyphenols in the juice blend, the increased antioxidant protection [in the body] after consumption of the juice blend, and the anti-inflammatory capacity in vitro, further research is warranted to evaluate whether juice blend consumption may provide reversal of risk markers in subjects with conditions such as arthritis, obesity, chronic viral diseases, cardiovascular disease and compromised cognitive function, as well as other conditions associated with chronic inflammation,» wrote lead author Gitte Jensen from Holger NIS Inc., a contract research laboratory.

«The intake of fiber and nuts during adolescence and incidence of proliferative benign breast disease» — such as fibrocystic breast disease; fibroadenomas; noncancerous breast lumps — but, is considered a marker for increased breast cancer risk.

But, given the capacity of methionine restriction to decrease the rate of free radical generation in internal organs, to lower markers of chronic disease, and to increase maximum longevity, this «disadvantage» may actually be a strong advantage.

So just to clarify: yes being overweight or obese does indirectly increase your risk factor for disease, because it's a marker, a signal, to show there's a problem.

Both patients have increased risk for disease (assuming they have unhealthy lifestyles), but their body's show this risk with different markers.

There are numerous tests that are shown to be more important markers of an increased risk of coronary artery disease than cholesterol.

There are numerous tests that are shown to be more important markers of an increased risk of coronary artery disease than cholesterol.There are many causes and risk factors for heart disease, including inflammation, high cholesterol, low testosterone, low thyroid, low estrogen, hypertension, high lipoprotein A, insulin resistance, diabetes, obesity, high homocystine, nutritional deficiencies and excessive oxidation, to name a few.

This is likely due to the impact of sugar consumption on heart disease risk factors, such as increased LDL cholesterol, increased blood pressure, obesity, insulin resistance and increased inflammatory markers (16, 18).

But, given «the capacity of [methionine restriction] to decrease the rate of [free radical] generation in internal organs, to lower markers of chronic disease, and to increase maximum longevity, ironically converts such «disadvantage» into a strong advantage and [it] fits well with the important role of [beans] in healthy diets like the [traditional] Mediterranean diet.

«Strong evidence indicates that dietary saturated fatty acids (SFA) are positively associated with intermediate markers and end - point health outcomes for two distinct metabolic pathways: 1) increased serum total cholesterol (TC) and LDL cholesterol (LDL - C) and increased risk of cardiovascular disease (CVD) and 2) increased markers of insulin resistance and increased risk of type 2 diabetes (T2D).

«Inflammation is likely to receive increasing attention as a marker of heart disease risk,» says Cyril Kendall, Ph.D., University of Toronto and study author.

Dr. Wilshire cited recently published, randomized control trials demonstrating that the increased intake of natural dietary fats in the context of a normal caloric diet improves the surrogate markers of atherosclerotic disease.

Interventions targeting modifiable risk factors (eg, smoking, inactivity, and poor diet) in adult life have only limited efficacy in preventing age - related disease.3, 4 Because of the increasing recognition that preventable risk exposures in early life may contribute to pathophysiological processes leading to age - related disease, 5,6 the science of aging has turned to a life - course perspective.7, 8 Capitalizing on this perspective, this study tested the contribution of adverse psychosocial experiences in childhood to 3 adult conditions that are known to predict age - related diseases: depression, inflammation, and the clustering of metabolic risk markers, hereinafter referred to as age - related - disease risks.