Sentences with phrase «increased duration of time»

Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem cells in the primary tumor, blocked metastasis of cancer cells from the primary tumor to the lungs, decreased the duration of chemotherapy required to induce remission and increased the duration of time after chemotherapy was stopped that the mice remained tumor - free.

Teach the pup to be comfortable with (even enjoy) small amounts of alone time and slowly increase the duration of those times.

Gradually increase the duration of the time your cat spends in the carrier, taking longer journeys to desirable destinations.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The Board or the HRC or the GNC may modify, suspend, or terminate the LTICP but may not, without the prior approval of our stockholders, make any change to the LTICP that increases the total amount of common stock which may be awarded (except to reflect changes in capitalization), increases the individual maximum award limits (except to reflect changes in capitalization), changes the class of team members or directors eligible to participate, extends the duration of the LTICP, reduces the exercise price of or reprices outstanding stock options or stock appreciation rights, waives the LTICP's minimum time period requirements for vesting and lapse of restrictions for restricted stock or RSRs, or otherwise amends the LTICP in any manner requiring stockholder approval by law or under the NYSE listing requirements.

Longer ‐ term bonds carry a longer or higher duration than shorter ‐ term bonds; as such, they would be affected by changing interest rates for a greater period of time if interest rates were to increase.

A few potted things the boycott and campaign has achieved: The International Code of Marketing of Breastmilk Substitutes (despite what Nestlé told the bloggers, it opposed the Code - scans of documents from the time are on our site), the Code's implementation in 70 countries to greater or lesser degrees, breastfeeding rates in countries taking action to stop malpractice increasing (Brazil from median duration 3 months in the 1980s to 10 months today), Nestlé changing its policy on milk nurses and baby pictures on formula, stopping specific cases of malpractice such as Nestlé promoting formula in Botswana as preventing diarrhoea etc. etc..

The increasing weight of your baby in your lower abdomen does not help, especially if you are doing things around the home or at work where you have to sit for long periods of time or are on your feet for some duration.

Although not directly comparable, our findings are in broad agreement with those from routine data in Scotland that have indicated a positive association between Baby Friendly accreditation, but not certification, and breastfeeding at 1 week of age.17 Our findings reinforce those of Coutinho and colleagues who reported that high exclusive breastfeeding rates achieved in Brazilian hospitals implementing staff training with the course content of the Baby Friendly Hospital Initiative were short - lived and not sustained at home unless implemented in combination with post-natal home visits.35 Similarly in Italy, training of staff with an adapted version of the Baby Friendly course content resulted in high breastfeeding rates at discharge, with a rapid decrease in the days after leaving hospital.36 In contrast, a cluster randomized trial in Belarus (PROBIT) found an association between an intervention modelled on the Baby Friendly Initiative with an increased duration of breastfeeding37 an association also reported from an observational study in Germany.38 Mothers in Belarus stay in hospital post-partum for 6 — 7 days, and in Germany for 5 days, with post-natal support likely to be particularly important in countries where mothers stay in the hospital for a shorter time, with early discharge likely to limit the influence of a hospital - based intervention.

The app monitors contractions in intervals with start time and duration by the press of a button, and then tracks how they increase over time.

For the same time period, 25 (6.9 %) of the 362 projects were determined to have an indirect impact on increasing the rates of breastfeeding initiation and duration.

Begin slowly, with 10 - minute walks 5 times per week and gradually increase the duration of your walks.

The initiative was introduced to the United Kingdom in 1993, but, although improvements have been reported, 3 rates of breast feeding in the UK are still among the lowest in the world.4 5 Recent reports from the National Institute for Health and Clinical Excellence (NICE) urge NHS units to become baby friendly to improve rates of breast feeding and save money.4 6 Data from the millennium cohort study, however, show that though participating maternity units in the UK increased rates of initiation of breastfeeding, duration did not increase.5 Other strategies are therefore required to support mothers in the UK to breast feed for the recommended time.

The next day — 2 times for half an hour, and gradually increase the frequency and duration of being outside until he starts spendning the whole day on the balcony.

Increase the duration of each session over time.

«Advances in numerical algorithms, automatic grid generation, and increased supercomputer power will eventually make the simulations of flood waves over large durations of time possible using Titan, and even more so with Summit,» Constantinescu said.

Both the duration of an individual copulation, and the overall time a mating pair spent copulating, were increased if the female performed fellatio.

«Timing of menopause onset may increase heart failure risk in women: Shorter reproductive duration, never giving birth among factors influencing risk.»

The odds of reaching recommended levels of leisure - time physical activity increased from 60 to 900 percent, depending on whether adult residents were former or current members of the program, and if the duration of their participation lasted for less than six months or for six or more months.

For shorter durations — a week, a month, even a year — the subjects» perception of time did not appear to increase with age.

The delay in school start time was associated with a significant (29 minute) increase in sleep duration on school nights, with the percentage of students receiving eight or more hours of sleep on a school night jumping from 18 to 44 percent.

The duration of the plumbeous vireo's songs decreased with increasing noise, whereas the gray vireo's songs were nearly 1.5 times longer than usual in the noisiest areas.

A statistically significant increase was observed relative to control at all hypoxic time points up to the 6 h duration of hypoxia.

At the same time, increasing depth and duration of drought, along with warmer temperatures enabling the spread of pine beetles has increased the flammability of this forest region — http://www.nature.com/nclimate/journal/v1/n9/full/nclimate1293.html http://www.vancouversun.com/fires+through+tinder+pine+beetle+killed+forests/10047293/story.html Can climate models give different TCR and ECS with different timing / extent of when or how much boreal forest burns, and how the soot generated alters the date of an ice free Arctic Ocean or the rate of Greenland ice melt and its influence on long term dynamics of the AMOC transport of heat?

In addition to disputing the relevance of your source trial (which doesn't appear to offer a duration or suggestion that the tests increase healthy lifespan of the mice in question), I'd like to point out that protection is less beneficial in the long term, because you can not stop damage from occurring completely no matter how well you defend an organelle, and that damage will accumulate over time.

This decrease in sleep duration has occurred over the same time as the increase in the prevalence of obesity and diabetes.

The amount of time spent in the sauna was deemed important, too, with longer - duration users seeing increased heart health benefits.

Creatine also increases the amount of time that maximal output can be performed — for example, it may increase the duration of a heavy lift, which means more repetitions at the same weight.

New Recommendations from the National Sleep Foundation - The Atlantic January 2015 - Poor Sleep in Adolescence Predicts Future Problems, Study Says - Los Angeles Times January 2015 - How Sleep Keeps You Healthy, Helps You Heal - Discovery News September 2014 - Lack of Sleep Increases Risk of Failure in School Among Teens - Science World Report, from Sleep Medicine August 2014 - Sleep Woes in Old Age May Be Linked to Brain Cell Loss - Health magazine August 2014 — University of Chicago Study: Getting More Sleep Could Cut Junk Food Cravings in Half — CBS News August 2014 — University of Montreal Study Shows Learning Is Best Enhanced During Sleep - Jewish Business News February 2014 - Link Found between Sleep Duration and Depression - Psych Central February 2014 - Less Sleep, More Time Online, Raises Risk for Teen Depression — National Public Radio

Every week, try to increase the amount of reps done in that same amount of time, or increase the duration of the set.

Once you have made some progress climbing the fitness mountain, you can increase the climbing duration to 2 - 4 minutes at a time, with at least 30 seconds of rest in between.

Creatine also increases the amount of time that maximal output can be performed - for example, it may increase the duration of a heavy lift, which means more repetitions at the same weight.

Overreaching is a less extreme form of overtraining but both are the result of increasing the intensity, frequency, or duration of training without allowing your body enough time to recover.

Since sprinting involves extremely short durations of time available for force production, it seems likely that strength training focused on explosive, short duration contractions (like ballistic training) will produce neural adaptations that increase high velocity - specific strength, and which transfer well to sprinting performance.

Measure, compare, add and subtract: lengths (m / cm / mm); mass (kg / g); volume / capacity (l / ml) Measure the perimeter of simple 2 - D shapes Add and subtract amounts of money to give change, using both # and p in practical contexts Tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks Estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; use vocabulary such as o'clock, am / pm, morning, afternoon, noon and midnight Know the number of seconds in a minute and the number of days in each month, year and leap year Compare durations of events [for example, to calculate the time taken by particular events or tasks]

Time, Time Measurement and Time Problems - Year 3 - 3 PowerPoint presentations and worksheets designed to teach pupils how to tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks; estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of eveTime, Time Measurement and Time Problems - Year 3 - 3 PowerPoint presentations and worksheets designed to teach pupils how to tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks; estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of eveTime Measurement and Time Problems - Year 3 - 3 PowerPoint presentations and worksheets designed to teach pupils how to tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks; estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of eveTime Problems - Year 3 - 3 PowerPoint presentations and worksheets designed to teach pupils how to tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks; estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of evetime from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks; estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of evetime with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of evetime in terms of seconds, minutes and hours; know the number of seconds in a minute and the number of days in each month, year and leap year; compare durations of events.

Objectives covered: Measure, compare, add and subtract: lengths (m / cm / mm); mass (kg / g); volume / capacity (l / ml) Measure the perimeter of simple 2 - D shapes Add and subtract amounts of money to give change, using both # and p in practical contexts Tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks Estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; use vocabulary such as o'clock, am / pm, morning, afternoon, noon and midnight Know the number of seconds in a minute and the number of days in each month, year and leap year Compare durations of events [for example, to calculate the time taken by particular events or tasks]

In this lesson, learners will be able: to tell and write the time from an analogue clock, including using Roman numerals from I to XII, and 12 - hour and 24 - hour clocks estimate and read time with increasing accuracy to the nearest minute; record and compare time in terms of seconds, minutes and hours; use vocabulary such as o'clock, am / pm, morning, afternoon, noon and midnight know the number of seconds in a minute and the number of days in each month, year and leap year compare durations of events [for example, to calculate the time taken by particular events or tasks] This lesson contains 77 interactive pages with lots of drag and drop activities and worksheet for extended work.

Compared with the last - gen TT RS, the 2.5 - liter turbo five in the new - for - 2018 model breathes better (thanks to new cylinder head with variable valve lift and duration timing on the exhaust cam), weighs nearly 60 pounds less (an aluminum block, magnesium upper sump, and other fat - reducing measures), and makes considerably more power, the byproduct of new port fuel injection and an increase in boost pressure from 18.1 to 19.6 psi.

Timing belt was replaced by timing chain which made it possible to increase the level of duration and lifespan up to 150,000 miles (250,000 km) of miTiming belt was replaced by timing chain which made it possible to increase the level of duration and lifespan up to 150,000 miles (250,000 km) of mitiming chain which made it possible to increase the level of duration and lifespan up to 150,000 miles (250,000 km) of mileage.

At low rpm, the i - VTEC intake valve timing and lift are optimized (low lift, short duration) for increased torque, which allows a wide range of 3 - cylinder operation.

At low rpm, the VTEC intake valve timing and lift are optimized (low lift, short duration) for increased torque, which allows a wide range of 3 - cylinder operation.

In that sense all analysis of stock market based on historical metrics do nt make much sense since composition of stocks is entirely different in different era and as more capital efficient business model evolve and their time to market cycle shrinks stocks likely to command higher valuations and suddenly lower valuations during short period of time like already happening for many technology companies and as influence of technology on overall cost structure of companies increases (for example: robotics replace many of employees cost etc) valuation matrix of most companies likely to get affected dynamically in short duration of time than in the past.

The fund currently has an average maturity of 0.97 years and duration of 0.83 years but at times of a favorable interest - rate scenario, it may increase the portfolio maturity little above one year, keeping in mind the safety and liquidity.

We can extend the duration of our financial assets to better protect against the risk of purchasing power loss, however, this increases the odds of permanent loss risk (the risk of being forced to take a loss at an inopportune time) and not having the funds when you need them.

Increase the behavior's duration, by rewarding him for longer periods of time.

After a short period of time, eventually increasing the duration, say «okay» or «come» to allow the dog to receive treats and praise.

Over time, owners can gradually increase the duration of stroking, but with any sign of aggression, the owner should stop the petting and begin a cooling down period with no physical contact.

As of September, travellers can spend more time getting to know Lisbon and Porto, as well as Madeira, Azores or Algarve, as TAP increases the duration of the stopover from three days to five.

- Adjusted abilities of some fighters and ARMS as below: Misango - Duration of immobility when masking up reduced (The Misanga is pleased) Scorpio - Increased curving, Increased expansion rate of charge attacks, Shortened wait time prior to scorpion jumping, Decreased extension speed, Decreased flotation during jump attacks, Decreased speed of charge attacks, Decreased homing during jumping attacks.