This is important since chronic excessive cortisol secretion leads to
increased fat deposition.
Not exact matches
Efficient
fat storage protects against
fat deposition on internal organs such as liver, kidneys and heart leading to
increased risk of diabetes.
«Our results suggest that centralized
fat deposition increased disordered eating risk above and beyond other known risk factors,» said Berner.
HFD can also
increase liver
fat levels quite rapidly (within days) as well as hepatic insulin resistance before significant
increases in peripheral
fat deposition occur (23).
One theory proposes that once the storage capacity of subcutaneous adipose tissue (SAT) depots is exceeded under conditions of energy excess, either as a result of impaired expandability and / or excessive hypertrophic growth,
fat deposition within visceral depots and non-adipose tissues including the liver, skeletal muscle and pancreas can ensue.93 This can subsequently lead to the development of systemic IR and a series of associated cardiometabolic disorders including dyslipidaemia, dysglycaemia, hyperinsulinaemia and hypertension.3 Expression of pro-inflammatory mediators including interleukins 1 (IL - 1), 6 (IL - 6), tumour necrosis factor alpha (TNF - α) and resistin, are also
increased which can further potentiate IR and promote atherosclerosis.
A high intake of fructose can especially be problematic, as this can lead to an
increase in
fat deposition in the liver and skeletal muscle, thus
increasing the risk of insulin resistance and type 2 diabetes (1).
The flight mechanism is bound to
increase * the burning up of the body calories which greatly minimize the presence of excess calories thus checking the
deposition of
fats.
A well documented relationship exists between chronically elevated levels of stress hormones and
deposition of excess
fat in the abdomen leading to obesity as well as
increased caloric intake, particularly
increased ingestion of
fats and sugars (Bjorntorp, 2001)