Microglial activation and
increased microglial density observed in the dorsolateral prefrontal cortex in autism.
A PET scanner can then detect the radioactive particles emitted from inside the brain, representing areas of
increased microglial activation before and after immune stimulation with LPS.
He believes that the process of microglial activation and ensuing neuronal damage is the same in males and females, but that the presence of female sex hormones
increases the microglial activation, leading to greater optic nerve damage and vision loss.
Not exact matches
The crossbred mice showed
increased oxidative stress and
microglial activation.
Patients with major depressive disorder (MDD) have
increased brain levels of a marker of
microglial activation, a sign of inflammation, according to a new study in Biological Psychiatry by researchers at the University of Manchester, United Kingdom.
As part of the study the team first used a form of optogenetics to establish that if gamma oscillations are
increased, they will energize
microglial cells in areas such as the hippocampus.
''...
microglial proliferation can be induced under inflammatory responses in the brain with an
increased production of ROS; therefore, microglia accumulate 8 - oxoG in nuclear DNA.»