Not exact matches
Critics of the inclusion of isoflavones in food claim that they
increase the
incidence of epithelial hyperplasia, which precedes cancerous
tumors, and that they cause goitre and hyperthyroidism.
We get heavily hyped drugs like Avastin, which shrank
tumors without adding significant time to cancer patients» lives (and
increased the
incidence of heart failure and blood clots to boot); Avandia, which lowered blood sugar in diabetics but raised the average risk of heart attack by 43 percent; torcetrapib, which raised both good cholesterol and death rates; and Flurizan, which reduced brain plaque but failed to slow the cognitive ravages of Alzheimer's disease before trials were finally halted in 2008.
The study also points to an
increased incidence of
tumors compared with those not operated on, but there the risks remained very small.
When the two mate, their offspring will sometimes inherit only the
tumor gene without the regulator, leading to
increased incidence of various cancers.
Cancer researchers have found that certain types of dental X-rays significantly
increased the
incidence of the most common type of brain
tumor in the United States: meningioma.
Additional evidence supporting the
tumor - promoting role of inflammation is the observation that individuals with chronic inflammation are more susceptible to cancers at the site of that inflammation — e.g. patients with Crohn's disease show
increased incidence of colorectal cancer.
P53: The protein p53 plays the role of
tumor suppressor, but creating a general
increase in p53 levels will, in addition to reducing cancer
incidence, also accelerate aging by reducing tissue maintenance through the creation of new cells.
An
increased latency and reduced
incidence in mammary
tumors also has been reported in C3H / HeJ and may be related to the Lps mutation (Outzen, H.J., et al., JNCI 75:917, 1985).
Increased expression of inflammatory cytokines correlates with higher
tumor grade, greater metastatic potential, and higher
incidence of resistance to treatment, all of which predict a poorer survival.
Alarmingly, and despite indisputable success achieved in the treatment of these malignancies, their
incidence in westernized countries during the last 3 decades has been
increasing more rapidly than that of most other
tumors.
One study that administered strawberries to mice with colon cancer found
tumor incidence to decrease as supplementation of strawberries
increased.
Chemically - induced colon
tumor incidence was
increased in rats fed the semipurified diets containing 23 % corn oil, safflower oil, lard or beef tallow (high - fat) as compared to those fed 5 % corn oil, safflower oil, lard or beef tallow diets (low - fat).
Spayed and neutered dogs have an
increased incidence of mammary, testicular and ovarian
tumors, as you might imagine, since these
tumors are affected by the hormones.
The
incidence of mammary
tumors in cats is statistically similar as dogs, as is the predisposition to
tumors increasing with each successive heat cycle.
Thyroid irradiation is associated with an
increased incidence of thyroid
tumors in all species, including humans and dogs.
This is basically what Allie was saying and I did not articulate well at all, that there are both benefits and risks associated with spay / neuter and while the S / N may
increase the
incidence of some cancers / conditions, it basically balances with the decrease of others, some of them more deadly such as mammary
tumors.
Ethoxyquin has been found to promote kidney carcinogenesis and significantly
increase the
incidence of stomach
tumors and enhanced bladder carcinogesis, according to several studies, including a recent one by The Department of Pathology, Nagoya City University Medical School, Japan.
As with humans,
incidence increases with age, and at 6, 8, and 10 years, 1 %, 6 %, and 13 % of dogs across all breeds report at least one mammary
tumor.
Cutaneous mast cell
tumors (MCT) were studied in several dog breeds revealing an
increase in
incidence in neutered females to 4 times that of intact females [10].