Sentences with phrase «increases in lung»

By tracking the mortality rates of people exposed to arsenic - contaminated drinking water in a region in Chile, the researchers provide evidence of increases in lung, bladder, and kidney cancer even 40 years after high arsenic exposures ended.

More pot smoking was associated with increases in lung capacity up to a level equivalent to about one joint per day for seven years or one joint per week for up to 49 years.

On the other hand, the continuing increase in lung cancer mortality among European women represents a challenge for cancer control, and the steady increase in pancreatic cancer deserves high priority for research.»

However, Esther and the UNC coauthors, who were not involved in the clinical trial, said that a statistically significant increase in lung function is thought to lead to fewer CF - related flare - ups over the course of a year.

In a study in the current issue of the American Journal of Preventive Medicine, researchers found that women working rotating night shifts for five or more years appeared to have a modest increase in all - cause and CVD mortality and those working 15 or more years of rotating night shift work appeared to have a modest increase in lung cancer mortality.

«We found that after using ivacaftor, patients experienced a dramatic increase in lung improvement in both the short and long term,» Altes said.

Hodgkin lymphoma survivors with a first - degree relative with cancer had a 1.3-fold increased risk for all cancers, a 3.3-fold increase in lung cancer, 2.1-fold increase in colorectal cancer, and a 1.8-fold increased risk for secondary breast cancer.

Not exact matches

And GSK expects more sales erosion for its ageing lung inhaler Advair in the key U.S. market - even before generic rivals are launched - due to increased pricing and competition.

However, current spirometers are not affordable for the majority of health care providers in many low and lower - middle income countries, and are not widely used despite a massive and increasing burden of chronic lung disease.

It turns out that talcum powder is dangerous if inhaled into baby's lungs, can irritate sensitive skin, and that its use has been linked to an increase in ovarian cancer.

The lungs are gaining blood vessels and the airways are increasing in diameter.

Further Proof It Increases Their Risk Of Lung Disease Later In Life

The symptoms of ammonia exposure are a burning sensation in the eyes, nose and throat; pain in the lungs; headache; nausea; coughing; and increased breathing rate.

Smoking around your baby or in the home weakens» babies lungs and causes an increased risk of SIDS.

For example, it can cause an increase in respiratory rate, 301 and tight swaddling can reduce the infant's functional residual lung capacity.299, 302,303 Tight swaddling can also exacerbate hip dysplasia if the hips are kept in extension and adduction.304, — , 307 This is particularly important, because some have advocated that the calming effects of swaddling are related to the «tightness» of the swaddling.

We are concerned also that intensive harvesting for fuel will lead to more aggressive clear - cutting and to increases in emissions of soot particles that contribute to lung disease.»

However, the impact of the two methylation - regulating enzymes was still seen at 10 to 15 months, when scientists found decreased expression of hundreds of genes — many of which are key tumor suppressor genes such as BMP3, SFRP2 and GATA4 — in the smoke - exposed cells and a five - or - more-fold increase in the signaling of the KRAS oncogene that is known to be mutated in smoking - related lung cancers.

Recent studies, they wrote, suggest that in addition to increasing asthma risk through obesity, fructose itself may cause inflammation in the lungs.

«What's really interesting is that we show that an increase in the amount of stomach fat and a lower density fat is associated with worse heart disease risk factors — even after accounting for how much weight was gained,» said Caroline Fox, M.D., M.P.H., former senior investigator for the National Heart Lung and Blood Institute and the study's senior researcher.

«We found that in young healthy mice the immune system overreacted to the influenza virus, which led to more inflammation, greater lung damage and increased mortality compared to healthy adults exposed to the virus,» says lead author Bria Coates, MD, Critical Care physician at Ann & Robert H. Lurie Children's Hospital of Chicago and Assistant Professor of Pediatrics at Northwestern University Feinberg School of Medicine.

After 20 years of research and almost as many years fighting industry groups in court for control of their data, government scientists can finally publish two papers showing that underground miners exposed to diesel fumes have a threefold increased risk for contracting lung cancer.

They found that fragments released by the break down of the lung's key proteins (collagen and elastin), are increased in the sputum of patients with TB.

In women, the predicted age standardised rate of deaths from lung cancer will increase by 9 % from 2009 to 14.24 per 100,000 of the population, while the death rates from breast cancer are predicted to be 14.22 per 100,000, which represents a fall of 10.2 % since 2009.

The current research suggests that pancreatic cancer cells that spread to organs that receive a blood supply rich in glucose and other nutrients, such as the liver and lungs, acquire metabolic adaptations to use these «natural resources» to increase their tumorigenic fitness.

Key findings in this study show that 5 - year survival for older lung cancer surgery patients is favorable; surgeons will be able to better individualize care for older lung cancer patients based on newly and uniquely linked data, and the prevalence of lung cancer is expected to increase as the population continues to age.

They found that longer telomeres were significantly associated with increased risk for lung cancer — specifically lung adenocarcinoma, which more than doubled in risk for every 1000 base pair increase in telomere length.

«This greater than expected survival in older patients selected for operative therapy is noteworthy,» said Dr. Fernandez, «especially considering that the prevalence of lung cancer is expected to increase as the population continues to grow older and more people survive into old age.»

The strength of the association between smoking and lung cancer is even stronger, with smokers being 35 percent more likely than non-smokers to get lung cancer, but in terms of epidemiology, the 16 percent increased risk of skin cancer in ever - users of UV tanning remains strong.

Working in human lung epithelial cells, researchers used a variety of techniques to show that flu infection increased activity of the PI3K and mTOR pathways and that BEZ235 restored PI3K and mTOR activity to pre-infection levels.

PET scans showed dramatically increased glucose metabolism in the lungs of 20 immune - compromised pediatric cancer patients with flu and other respiratory infections compared to patients without infections.

UT Southwestern researchers found that the proteins SRC - 1 and SRC - 2 activate genes inside the fetus» lungs near full term, resulting in an increased production of surfactant components, surfactant protein A (SP - A), and platelet - activating factor (PAF).

They demonstrated in an animal model that there is an association between advancing age and increased inflammation processes, especially if the lung is additionally exposed to cigarette smoke.

An analysis of nearly 273,000 patients showed that between 2013 and 2014 there was a 1 % increase in the percentage of breast, lung, and colorectal cancers diagnosed at the earliest, most treatable stage.

Key Findings Researchers found a 1 % increase in stage I diagnoses for four of the five cancers detectable by screening: breast (from 47.8 % to 48.9 %) and cervical cancer (47.3 % vs. 48.8 %, although this difference was not statistically significant) in women, and lung (from 16.6 % to 17.7 %) and colorectal cancer (22.8 % vs. 23.7 %) in men and women.

As the use of CT scans to assess lung disease increases, monitoring ECAC in the appropriate patient group could be extremely valuable to clinicians.»

Specifically, increases in serum cotinine were statistically significantly associated with lung cancer, all cancers, and heart disease.

In the past five years, the number of lung transplantations carried out has increased by about 20 %.

In this study, immune cell infiltration of the lungs increased, and Th2 responses became more prominent.

Among patients with non-small cell lung cancer (NSCLC) fueled by ALK gene alterations who were being treated with crizotinib (Xalkori), a decrease in the number of circulating tumor cells (CTCs) harboring increased copies of the ALK gene over the first two months of treatment was associated with increased progression - free survival.

Lung cancer causes the most cancer - related deaths in the United States, and researchers are searching for new cellular targets to increase survival rates.

Cardiologists from Musgrove Park Hospital, Taunton, writing in the Journal of the Royal Society of Medicine, say the condition, which causes an excess collection of watery fluid in the lungs, is likely to become more common with the increase in participation in endurance sports.

Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem cells in the primary tumor, blocked metastasis of cancer cells from the primary tumor to the lungs, decreased the duration of chemotherapy required to induce remission and increased the duration of time after chemotherapy was stopped that the mice remained tumor - free.

«Even in those who had never smoked we found that accelerated loss of lung function increased their risk of airway obstruction and COPD.»

Because it is so deadly and because the number of new cases is increasing, it is predicted to be the second leading cause of cancer deaths in the western world by 2020, trailing only lung cancer, he adds.

Four years ago, she was diagnosed with pulmonary fibrosis, a condition that causes scarring in the lungs and results in increasing shortness of breath.

Upon receiving two cycles of treatment with lenalidomide, the patient's breathlessness, fatigue, daily activity, and quality of life showed significant improvement, and her lung function testing demonstrated a remarkable increase in vital capacity.

«What we saw in mice lacking STIM1 — whose T - cells can not generate calcium signals — is that the number of mycobacteria in their lungs was dramatically increased, resulting in excessive inflammation,» says Stefan Feske, MD, an associate professor of pathology at NYU Langone and the study's senior author.

Griffiths also notes that emphysema, a lung disease common in smokers, is marked by a loss of connective tissue and may be related to increased MMP - 1 levels.

In Grand Junction, Colo., radioactive mill tailings were used as building materials, causing increased risk of lung cancer, according to the Environmental Protection Agency.

In particular, neonates from the treatment group had significantly lower rates of bronchopulmonary dysplasia, a lung condition of newborns that increases the risk of chronic lung disease during childhood.