Sentences with phrase «increasing cell size»

We isolated a locus that contributes substantially to this wing size difference by increasing cell size and cell number.

firstly, when the perturbation that increased cell size was lifted, the meristem cells accelerated their divisions and consequently returned to their normal size; and

Not exact matches

No. 4: CAR - T takes a backseat Research into chimeric antigen receptor T - cell (CAR - T) therapy has captured the attention of investors over the past two years, but safety risks could emerge as trial sizes increase, and that could help shift attention to other promising anti-cancer approaches, including NantKwest's (NASDAQ: NK) natural killer cell approach and soon - to - IPO Editas» CRISPR / Cas approach.

A human sex cell was imagined to contain a miniature homunculus, which increases in size until it becomes an embryo, an infant, and eventually an adult woman or man.

Blakemore argues that a single gene mutation could in fact have been the cause of this increase - for in fact only one extra cell - division step would cause a doubling of brain size.

Anabolic steroids work by helping the body's muscle cells produce more protein which, as long as the athletes works out, leads to increased muscle size and strength and, at the same time, also allows the body to produce more ATP, the «fuel» muscles need to move.

CITY Lips has a proprietary collagen peptide formula (using Celadrol ™ and Oligopeptide Technology *) that actually causes the cells in your lips to produce more collagen which in turn physically increasing the size of the lips.

They produce energy by pumping liquid electrolytes through a cell, and increasing their capacity is simply a matter of increasing the size of the storage tanks for the electrolytes.

After just a few hours, they could clearly observe how the contact points between the affected neurons and their neighbouring cells increased in size.

In humans, basal progenitors can undergo multiple rounds of cell division, thereby substantially increasing neuron number and ultimately the size of the neocortex.

Further investigation revealed that loss of surrounding cells causes multiple changes in cell communication, which impairs bone cells» ability to multiply and increase in size.

The study shows lithium chloride, a drug often used to treat bipolar disorder, can increase the size of primary cilia in several cell types.

Kress, now a postdoctoral researcher at Yale, thinks the cell uses filopodia to increase the size of the area it can explore in a given time.

Higher efficiency means more electricity produced for a given size of solar cell, which increases power output and lowers overall system costs.

B cell treatment also quickly reduced the size and improved the healing of chronic skin ulcers in the diabetic mice, increasing the number of both nerve endings and blood vessels in regenerated tissue.

Accommodating these extra structures into the daughter cell's nucleus might be what increases the overall cell size.

DNA content in the mutant cells increased and some of the resulting cell sizes were larger.

As more saturated fatty acids enter the cell, those islands grow in size, creating increasing inelasticity of the membrane and gradually damaging the entire cell.

The team found that the five - week eruption supplied enough dissolved iron to increase the number of phytoplankton cells within a region of the North Atlantic stretching across 570,000 square kilometers — or 220,000 square miles, about the size of France.

These results collectively suggest that neural stem cells need MSI1 to generate enough neurons for normal brain size, but the presence of MSI1 also increases the vulnerability of these cells to Zika infection, leading to the death of the population which ultimately results in microcephaly.

Additionally, overexpression of POSTN in human mammary epithelial and breast cancer cells resulted in enhanced tumor growth and metastasis (Wang et al., 2013), which is similar to a colon cancer cell model where overexpression of POSTN resulted in an increase in the number and size of liver metastases (Bao et al., 2004).

If Lsd1 is ablated, the fat cells increase in size, for example (right).

The researchers selectively ablated Lsd1 and inactivated its catalytic activity in brown adipocytes, which triggered a profound whitening of brown adipose tissue: The colour of the brown fat cells became paler, their size increased and they started to store energy instead of expending it.

Treatment also restored a more normal size to anterior horn cells, and increased both total muscle area and myofiber diameter.

Complex surface attributes, such as its topography and chemical properties, are not explored here but are expected to influence cluster sizes in some natural environments by increasing the complexity of fluid flow patterns, inducing short - range cell relocation and modifying the long - range relocation mechanism.

With the size decreasing of quantum dots, the distinction of band energy between hole transport layer and optical absoprtion layer will be increased, which can improve the open - circuit voltage of the solar cells.

Now, in a new study in the journal Cancer Cell, Shaw and a team of scientists at the Salk Institute for Biological Studies found that phenformin, a derivative of the widely - used diabetes drug metformin, decreased the size of lung tumors in mice and increased the animals» survival.

In Arabidopsis roots, it was shown that BR - mediated cell elongation leads to exit from the meristem and subsequent decrease in meristem size and growth rate after an initial growth increase (González - García et al., 2011; Chaiwanon and Wang, 2015).

It also showed that their immune cells were increasing noticeably in both size and activity, suggesting that these cells were cleaning up the high levels of amyloid proteins.

Cells closer to the QC show a rather similar yet slightly increasing size, while cells further away increase strongly in length exponentially (FigCells closer to the QC show a rather similar yet slightly increasing size, while cells further away increase strongly in length exponentially (Figcells further away increase strongly in length exponentially (Fig 1C).

Based on a number of studies, we postulate that to transmit nutritional information from the fat body to the insulin - producing cells, the fat - body — derived signal would need to have the following properties: (1) it should be produced in the fat body and secreted into the hemolymph, (2) its expression and / or secretion should be amino acid - and TOR - sensitive, (3) it should act downstream of TOR signaling to stimulate ILP secretion from the insulin - producing cells, and (4) its secretion should increase IIS activity in the entire body, resulting in increased body size.

Meanwhile, increasing temperature and ocean warming may lead to the reduction of diatom production as well as cell size, inducing poleward shifts in the biogeographic distribution of diatoms.

Male wing size increases by 45 % through cell size and cell number changes when the ws1 allele from N. giraulti is backcrossed into a N. vitripennis genetic background.

«Fat gain is due mainly to increased fat cell size,» explains Long.

Pollak says the hormone does make people produce more insulin - like growth factor 1, which stimulates cell division as well as an increase in cell size.

The rainbow mechanism (which mixed targeting the cells with NS - C225 and NSP - PSMA and exposing them to the two simultaneous laser pulses, 532 nm and 787 nm) resulted in an increase in PNB size (lifetime) of almost one order of magnitude compared with the response of the same cells to mono - pulse treatments (Table 2).

Extensive testing shows that micro sizing drug - cell interactions reduces cost of experiments significantly as well as increasing productivity as it enables more experiments to be done on the same platform at the same time.

To mimic the in vitro hypoxic response in vivo, we developed a xenograft model based on the hypothesis that with increasing xenograft sizes, there will be a parallel increase in hypoxia due to rapid cell proliferation and restricted blood supply to the xenograft cells.

Instead, a very small number of neurons specifically activated by learning show an expansion of structure that's both surprisingly extensive — there's a dramatic increase in the size and complexity of the affected neurons — and yet highly restricted to a small subset of cells.

A working muscle can only differentiate between amounts of load, to which it can only react by generating the amount of force needed for adapting to the task at hand, eventually entering the hypertrophy mode — an increase in size of skeletal muscles through a growth in size of its component cells.

Hypertrophy is the process of increasing the number of cells within an organ or tissue (such as muscle tissue), thereby increasing its overall size.

While it works great for adding size to your frame, it also increases water retention in muscle cells in order to enhance protein synthesis, so water weight gain is to be expected when taking it regularly.

Testosterone causes an increase in the size of your muscle cells, this means that each individual muscle cell will grow.

You generally increase muscle size by increasing the size of muscle cells, but the fiber remains more or less the same (i.e. the balloon stays the same).

These effects were marked by a reduction in elevated cortisol and adrenal gland size, an increase in the weight of the thymus and spleen, and replenishment of depleted T cells.

Hypertrophy is an increase in the size of a muscle through an increase in the size of its component cells.

Secondly, given there was no overall reduction in adipose depot weight in IER (50 % or 100 % ER / alternate days) fed mice, this reduction in adipocyte cell size must reflect an increase in adipocyte number (i.e. adipogenesis).

Excessive insulin leads an increase in the size of fat cells.

Research (Fleck & Kraemer, 2004) shows that when you're doing 8 - 12 reps, this is the optimal area for muscle hypertrophy (increasing size of skeletal muscle through the increase in size of component cells).

It inhibits cell replication, changes membrane structure, reduces the size of villi that absorb nutrients, and increases secretions that cause oxidative damage.