Sentences with phrase «increasing effects of impacts»

The Impact Mantle achieves this by increasing the effect of impact weapons like the Charge Blade, Hammer and Hunting Horns, but also adds the stun effect to weapons that don't normally have it, like Dual Blades.

Not exact matches

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

«We found that it not only increases the positive effect toward a favorable interaction, but it also diminishes the impact of a negative impression.

Commuting has an effect on performance as it increases anger and resentment at work, absenteeism, and has a negative impact on punctuality and the ability to focus and perform at the same level as other colleagues who live nearer to the place of work.»

The ability to talk back, send comments or share a link (all of which generate positive impact with minimum effort) has the same psychological effect, which is why an increasing number of websites are choosing to use this technique.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

These risks include, in no particular order, the following: the trends toward more high - definition, on - demand and anytime, anywhere video will not continue to develop at its current pace or will expire; the possibility that our products will not generate sales that are commensurate with our expectations or that our cost of revenue or operating expenses may exceed our expectations; the mix of products and services sold in various geographies and the effect it has on gross margins; delays or decreases in capital spending in the cable, satellite, telco, broadcast and media industries; customer concentration and consolidation; the impact of general economic conditions on our sales and operations; our ability to develop new and enhanced products in a timely manner and market acceptance of our new or existing products; losses of one or more key customers; risks associated with our international operations; exchange rate fluctuations of the currencies in which we conduct business; risks associated with our CableOS ™ and VOS ™ product solutions; dependence on market acceptance of various types of broadband services, on the adoption of new broadband technologies and on broadband industry trends; inventory management; the lack of timely availability of parts or raw materials necessary to produce our products; the impact of increases in the prices of raw materials and oil; the effect of competition, on both revenue and gross margins; difficulties associated with rapid technological changes in our markets; risks associated with unpredictable sales cycles; our dependence on contract manufacturers and sole or limited source suppliers; and the effect on our business of natural disasters.

It is also the case that the increased economic activity spurred by opening new areas to road travel (which Price decries) has a positive economic impact regardless of its effect on traffic.

Because it reduces price and increases volume, it suggests that if Uber ultimately succeeds, the company could have a much bigger impact on urban mobility, labor, the environment, local economies and the national transportation infrastructure than we've all supposed — and its effects could confound the expectations of its harshest critics.

«Negative publicity or public opinion resulting from these matters may increase the risk of reputational harm to our business, which can impact our ability to keep and attract customers, our ability to attract and retain qualified team members, result in the loss of revenue, or have other material adverse effects on our results of operations and financial condition.»

This had the effect of increasing revenues and spending by comparable amounts, with no impact on the budgetary balance.

[7] In fact, however, because proxy access» effect will be to increase the number of short slates, albeit to an uncertain extent, its impact on corporate governance likely will be analogous to that of cumulative voting.

Amid this cloud of uncertainty, investors must suddenly confront the possibility of increased protectionism, the severity of the measures and its effect on regions, companies and impacted sectors.

This figure is a good deal higher than the 1.7 per cent for the latest year - ended rise in the CPI, but the pick - up includes the effect of dropping out the impact of the health insurance rebate, which reduced the CPI in the March quarter 1999, some further effects from past movements in crude oil prices, and an increase in tobacco taxes in the December quarter.

It is not surprising then that after an exhaustive study of the impact of the green revolution in five countries, Keith Griffin concluded that the transfer of capital - intensive, market - oriented technology not only had little positive effect on malnutrition, but actually increased the range of inequality, wiped out many subsistence farmers (usually women in most of the poorer countries), and plunged them further into destitution.

If one could definitively measure long - term effects, which is a virtual impossibility, a case might be made that such open and obvious untruths have a harmful impact on the health of the republic, increasing permanently the levels of distrust and cynicism.

A diet rich in Omega - 3 can help the brain increase mental alertness and concentration levels at any age, but can also be shown to help slow the effects of normal age related memory loss and increase resistance to stress and its impact on mood.

The high percentage of athletes reporting that they continued to play despite experiencing concussion symptoms, while similar to the rates reported in other studies, is concerning, as the failure to diagnose concussions in athletes can lead to further damage to the brain before full recovery, expose them to the cumulative effects of injuries and increased risk of second impact syndrome.

With youth sports concussion safety laws in place in all 50 states, increased public awareness about concussions, and growing concernabout the long - term effect of repetitive head impacts, the demand for concussion education, not just for parents, coaches, and athletes, but for health care professionals as well is at an all - time high, and promises to go even higher in the coming years.

Today's decision is likely to be welcomed by Manchester city council, but there are widespread concerns about the social impact of building the new casinos, in particular the effect they may have of increasing problem gambling.

The Executive Budget proposes a different approach, whose effect would be to further increase the progressive impact of the personal income tax.

The housing sector in Scotland is continuing its recovery from the effects of the international financial downturn which impacted on both housing developers and would - be home buyers and increased pressures on living standards across households generally.

But Alhassan Tampuli speaking on the increase said apart from the effect of the hurricanes, the international price at which fuel currently sells also has had an impact on the price build - up as well as the cedi - dollar rate.

Poloncarz noted the impact poverty in the county has on the greater community along with several actions his administration has undertaken to address poverty and its myriad effects, including the imminent opening of the new Erie County Health Mall; a new partnership with Catholic Health, the Buffalo Public Schools and the Say Yes program to expand social work, mental health services, and clinics into Buffalo Public schools; and increased collaborations with partners to bolster workforce development.

They'll answer your questions on a variety of topics, including whether the human lifespan will continue to increase, what impact antiaging research could have on global demographics, and what the latest research says about what you can do to combat the ill effects of growing older

Professor David Schultz, one of the authors of the guest editorial, said: «One of the long - term effects of climate change is often predicted to be an increase in the intensity and frequency of many high - impact weather events, so reducing greenhouse gas emissions is often seen to be the response to the problem.

Increased frequencies of pest and disease outbreaks resulting from these changes may have additional negative effects on agricultural production and human well - being, with impacts projected to worsen.

The study found that combining the two drugs had an increased effect of killing of cancer cells, while individually, the drugs have considerably less impact on cell viability.

It is possible that medical advances over the past few decades in the treatment of type 2 diabetes, hypertension and high cholesterol levels have had a greater impact on people who are overweight — which increases the risk for these conditions — whereas the effect was much smaller in those of normal weight.

Because of the clockwise nature of ocean circulation around Greenland, most of the freshwater increase, up to 70 percent, is being driven toward the Labrador Sea, magnifying its impact and increasing the possibility of significant effects on the AMOC, said Qian Yang, the paper's first author and a PhD student at USF whose dissertation, in part, includes this research.

Dr Li said the latest research findings give a better understanding of changes in human - perceived equivalent temperature, and indicate global warming has stronger long - term impacts on human beings under both extreme and non-extreme weather conditions, suggesting that climate change adaptation can not just focus on heat wave events, but should be extended to the whole range of effects of temperature increases.

The researchers also set parameters to assess the impact of the effects of the high - fat, high - calorie diet on mouse pancreas tissue, such as increased inflammation and other biological signs that indicate pancreas problems.

The authors suggest that for the future «A more complete clinical analysis should entail follow - up for at least 2 or 3 years and with an increased dose range; such a design presumably would reveal the impact of dose on both acute and late RT - related toxicity and thereby strengthen the associations observed in this analysis of acute effects.»

«Moving from a polluted neighbourhood to a clean area and vice versa would allow us to explore the persistence of the effect related to perinatal exposure and to evaluate the impact of exposure to increased air pollution concentration later in life,» says Heinrich.

In general, the review found that increases in out - of - pocket costs seemed to have a lower impact on reducing utilization for specialty drugs as compared to the effects reported for non-specialty drugs, probably because specialty drugs often have no medically comparable alternatives, Doshi and her coauthors note.

Direct effects are impacts to trees that arise directly in response to changes in temperature and precipitation; indirect effects are secondary impacts, such as increased number of fires associated with warming temperatures, which then affect trees and forests.

The signature effects of human - induced climate change — rising seas, increased damage from storm surge, more frequent bouts of extreme heat — all have specific, measurable impacts on our nation's current assets and ongoing economic activity.

-- 7) Forest models for Montana that account for changes in both climate and resulting vegetation distribution and patterns; 8) Models that account for interactions and feedbacks in climate - related impacts to forests (e.g., changes in mortality from both direct increases in warming and increased fire risk as a result of warming); 9) Systems thinking and modeling regarding climate effects on understory vegetation and interactions with forest trees; 10) Discussion of climate effects on urban forests and impacts to cityscapes and livability; 11) Monitoring and time - series data to inform adaptive management efforts (i.e., to determine outcome of a management action and, based on that outcome, chart future course of action); 12) Detailed decision support systems to provide guidance for managing for adaptation.

Direct effects of climate change on trees and forests, such as warmer, wetter conditions improving forest productivity or warmer, drier conditions increasing tree mortality, will be secondary to the impacts of altered forest disturbance regimes, such as changes in forest fire behavior and area burned.

indirect effect A secondary impact to a system from a change that was caused by shifting climate conditions, such as increased fire frequency, which is a result of drier conditions caused by an increase in temperature.

This increase may have contributed to the protective effects of klotho, counteracting the detrimental impact of Alzheimer - related toxicity on the brain.

There is a clear impact on global temperature, too, though the mechanisms are complex: heat released from the oceans; increases in water vapor, which enhance the greenhouse effect, and redistributions of clouds.

Taking the microbiome into account may be important for accurate phenotype - genotype analysis due to the increasing awareness of the impact the microbes have on different body sites, through the products they produce, their ability to protect against invading organisms, their direct interaction with the cell structures and the extracellular milieu, provoking inflammatory or immune responses, and many other effects.

The impact of increased tiger mortality through poaching or human conflict is well known [3], [4], yet the effect of infectious disease outbreaks remains largely unstudied.

These chemicals are associated with a wide range of health impacts including respiratory problems, increased risk of cancer, birth defects, and neurological effects.

While low testosterone levels do indeed have a great number of undesirable physical side effects — increased body fat, less energy, low libido all among them — low levels can also carry with them a tremendous psychological impact.

The study authors concluded, «We provide a more complete picture of the impact of chocolate consumption in vascular health and show that increasing flavanol content has no added beneficial effect on vascular health... However, this increased flavanol content clearly affected taste and thereby the motivation to eat these chocolates.

Hormones and digestive ailments can impact the scale readings, time of the day effects weight, workouts can increase weight (due to retention of fluids caused by inflammation — a direct response of working out), even one glass of water can skew the scale numbers — and if those numbers aren't where you expect and want them to be, you can be thrown into a downward spiral of despair.

In effect, there are a lot of factors that warrant the increasing trend of online dating in the 21st century; its positive impacts and several success stories speak volume about its significance.

The panel aims to explore topics such as empathy's place in the sea - change in the production and distribution of films, how increasing the number of women at all levels of the film industry will effect this, and its impact on film criticism and influence on society as a whole.