Sentences with phrase «increasing immune suppression»

«If we could add a drug that acts on a different target without increasing immune suppression it could be very valuable.»

Not exact matches

Onion A increases anti-tumor immune response by inhibiting the immune suppression actions of macrophage and myeloid derived suppressor cells (MDSC).

New Zealand's peak UV - B levels could put the country's inhabitants at increased risk of skin cancer, cataracts, and perhaps immune system suppression.

Sustained angiogenesis, the growth of new blood vessels, and the suppression of the immune system are hallmarks of cancer, with an increasing amount of evidence demonstrating that these two activities are interrelated.

iTeos» pipeline addresses key unmet needs in immuno - oncology: the inhibition of immune suppression in inflamed (hot) tumors and the increase of immunogenicity in non-inflamed (cold) tumors.

Intriguingly, we also found that rare individuals moved out of the IRP category by a process of immune suppression, including increases in IL - 6 and IL - 10 and decreases in the number of CD3 + CD8 + CD28 - cells.

This method increased the amount of anti-inflammatory proteins produced by the MSCs, enhancing the suppression of immune cells.

Dr. Gollnick's laboratory explores how tumor cells co-opt the host immune system to promote chronic inflammation that leads to increased vascularization, suppression of anti-tumor immunity and increased tumor cell proliferation and migration.

-LSB-...] Chronically elevated cortisol levels are both inflammatory and catabolic and cause a myriad of disorders including: thyroid and metabolic dysfunction, cognitive decline, low serotonin levels resulting in depression, irritability, anxiety, carb cravings, immune suppression, altered glucose metabolism, elevated lipid levels, increased blood pressure, low melatonin levels resulting in altered sleep patterns, musculoskeletal issues resulting in difficulty recovering from exercise and possible subsequent injuries.

Paradoxically, inflammation increases with age — what you're actually getting is immune dysfunction rather than simply suppression of the immune system.

Unfortunately, treatments for these conditions can involve suppression of the immune system to the point that the patient is at increased risk for opportunistic infections and cancer.

Serum cholesterol levels below 190 mg / dl or so indicate immune suppression and increased risk of infectious disease — whatever the age of the human in question.

Deleterious effects include endocrine disruption, thyroid suppression, immune system suppresion, suppression of sperm production, DNA breakage and increased incidence of leukemia, breast cancer, colon cancer, infertility, growth problems and subtle changes in sexually dimorphic behaviors.

Worse still, chronic stress and increased cortisol levels can result in greater inflammation coupled with immune suppression which is a deadly combination regarding one's ability to combat disease.

Feline leukemia virus causes an infection leading to immune system suppression and anemia; it increases susceptibility to other infections and to cancer, and is usually fatal.

Potential side effects include: stomach ulcers, delayed wound healing, thyroid hormone suppression, immune suppression, increased appetite, fluid retention, weak bones, and thinning hair / hair loss.

Over the long term, excessive discharge of epinephrine and norepinephrine can lead to the suppression of cellular immune functioning; produce hemodynamic changes, such as increased pressure in heart rate; provoke variations in normal heart rhythms; and produce neurochemical imbalances that may contribute to the development of psychiatric disorders.