Sentences with phrase «increasing number of mutations»

The decline in skeletal muscle function associated with human ageing can be ascribed to an increasing number of mutations in satellite cells — the resident stem cells of skeletal muscle.

Even at the same growth rate (i.e. similar fitness levels), some, but not all, nutritional limitations significantly increase the number of mutations.

Another environmental risk factor, cigarette smoking, was associated with markedly increased numbers of mutations.

Not exact matches

At last year's Brainstorm Health conference in San Diego, Bergh found himself sitting at dinner with Othman Laraki, the cofounder and CEO of Color Genomics — a company that extracts the DNA from a customer's submitted saliva sample and then looks for a set number of gene mutations known to be associated with increased risk for developing certain hereditary cancers or heart conditions (depending on the test).

And their findings coincided: the number of slightly deleterious mutations per individual does indeed increase with distance from Southern Africa, which is consistent with an expansion of humans from that region.

But the mutations from a growing number of older fathers may also account for a portion of the recent increase in autism.

This rapid growth has left a mark on the human genome, researchers are finding, drastically increasing the number of very rare mutations in our DNA.

However, I did obtain a number of female Z116A transgenic mice that were heterozygous for the myostatin mutation, and as shown in Table 1 and Figure 2a, these mice exhibited further increases in muscle weights compared to Z116A mice that were wild type for myostatin.

Although further investigation is under way, no evidence currently suggests that these mutations are leading to an unusual increase in the number of H1N1 infections or a greater number of severe or fatal cases.

Their tumors harbor an increasing number of DNA mutations, which attract the attention of immune system T cells that hunt down and destroy cancer cells.

Overall, the number of iPSC mutations — which the researchers suspect were present but undetected in donor blood cells — increased linearly with donor age.

CCG uses high - throughput techniques to identify and study mutations, large rearrangements of the genome, increases and decreases in DNA copy number, chemical modifications to DNA, and changes in the expression of RNA and proteins.

This further narrowed their target to a number of mutations in the K13 - propeller that were strongly associated with increased parasite survival rates when exposed to artemisinin in the lab.

Carriers of the genetic mutations will undergo more frequent surveillance for breast and ovarian cancer, including an increased number of mammograms and MRIs.

Clinical studies identify FLT3 ITD mutations associated with higher numbers of leukemic cells, increased incidence of relapse and decreased overall survival.

A research team led by an award - winning genomicist at Western University has developed a new method for identifying mutations and prioritizing variants in breast and ovarian cancer genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed.

We found mutations in a gene called «POT1» that increased the risk of melanoma in a small number of these families.

With increasing mutation burden, numbers of driver mutations increase, but not linearly.

TUESDAY, March 28, 2017 (HealthDay News)-- An increasing number of American women who don't have breast or ovarian cancer are being tested for BRCA and BRCA2 gene mutations associated with those diseases, a new study shows.

Over time, the number of clear dogs available will increase and use of dogs with the mutation can be phased out.

With the entire world watching the recent Fukushima events and the rising of radiation levels, reported mutations and increasing numbers of cancer patients (Kudo himself died of cancer) his oeuvre can be regarded as a valid political statement of contemporary culture on a global scale.

Many types of phytoplankton do increase their numbers rapidly but they propagate primarily by asexual reproduction, which makes it less likely for populations to accumulate the genetic mutations that could allow them to adapt.