The complexity of the 3 - D multicellular environment can be overwhelming, Betzig says, but the clarity of his team's imaging permits them to computationally «explode» apart
the individual cells in tissue to focus on the dynamics within any particular one, such as the remodeling of internal organelles during cell division.
Not exact matches
Even an
individual cell in our bodies is a responsive entity whose behavior can be studied
in tissue culture.
They would add a liter of the
tissue to two liters of seawater and shake the mixture 75 times — no more, no less — to make «the
individual light - producing
cells pop out of the
tissue,» according to Bill Ward, a bioluminescence researcher at Rutgers University
in New Jersey who was a post - doc
in Cormier's laboratory.
The
individual live
cells are not communicating, and «
cells in a
tissue have to communicate with each other».
Still, how melanoma
cells join into tumors — whether by
individual cells coming together or small or large clusters of
cells doing so — follows the same pattern as breast
tissue cancer
cells: Cables are extended to reel
in other
cells or clusters.
From
tissue and
cell samples from five glioblastoma patients, the scientists obtained 33
individual cancer
cells capable of reproduction, which grew into very different tumors
in the lab.
How do
individual biomolecules move
in live
cells,
tissues, or organisms?
Recent advances
in single -
cell genomics technology has made it possible to separate
individual cells from different
tissues and organs, and measure the sets of RNA messages — called the transcriptome — which help give each
cell its own identity.
Kuo's method starts with
tissue fragments rather than
individual stem
cells and grows them
in a gel partly exposed to air instead of submerged
in nutrient medium.
Split Pool Ligation - based Transcriptome sequencing (SPLiT - seq) is a scalable technique for characterizing RNA
in individual cells that can be used to identify the various
cell types found
in the brain and other
tissues.
The new method has numerous advantages: researchers can sample
individual cells of a
tissue culture directly
in the petri dish.
Therefore, adult stem
cells become exhausted
in aged
individuals due to telomere length shortening that results
in increased healing times and organ
tissue degradation from inadequate
cell populations.
Importantly,
individual classes of inhibitory neurons are quite sparse
in the brain, so any unique features of those
cells would likely have been lost
in earlier studies that looked at the
tissue as a whole.
The researchers showed that ABA concentration changes and waves of ABA movement could be monitored
in diverse
tissues and
individual cells over time and
in response to stress.
Such characteristics enable iPSCs to be used
in several applications of regenerative medicine, particularly because they can be derived from an
individual's own
cells so
tissue rejection problems are not encountered.
In myotonic dystrophy and other related neurological disorders, the symptoms stem from repeated individual nucleotides, or «building blocks,» in the RNA in muscle tissue cells that can build up over tim
In myotonic dystrophy and other related neurological disorders, the symptoms stem from repeated
individual nucleotides, or «building blocks,»
in the RNA in muscle tissue cells that can build up over tim
in the RNA
in muscle tissue cells that can build up over tim
in muscle
tissue cells that can build up over time.
The research, using
cells from the Breast Cancer Now
Tissue Bank and due to be published
in Nature Communications, also shows that the epigenetic changes are inherited as long as the
cell divides, and that the team's manipulations permanently and negatively affected the biology of a normal breast
cell from a healthy
individual.
In healthy
individuals, MDSCs regulate immune responses and
tissue repair, and the population of these
cells rapidly expands during inflammation, infection and cancer.
The interactions range from
individual biomolecules,
cells up to
tissues and organs and might occur
in a broad range of timescales.
For the first time, it is now possible to read the genetic code of
individual cancer
cells in their original location
in the
tissue.
Multiple sclerosis (MS) is among the most common neurological diseases
in young adults, affecting 350 000
individuals in the United States and 2 million worldwide.1 Prevailing thought is that MS is an autoimmune disorder whereby an unknown agent or agents triggers a T
cell — mediated inflammatory attack, causing demyelination of central nervous system
tissue.2
-- We can now use sequencing chemistry directly
in cancer
tissue speciemens to read the genetic code and obtain information of specific RNA molecules
in individual cells in their original context
in the
tissue.
Clarke notes that this kind of work — reprogramming normal
cells to replace damaged
tissues or organs
in regenerative medicine, or even growing
cells from an
individual's cancer to determine what the best treatment is — speaks to the doctrine rather than challenges it.
However, researchers have been skeptical of blood - based epigenetic studies for one main reason: While the genome is the same
in any
cell from the same
individual, the epigenome necessarily changes from
tissue to
tissue.
In the current study, lead authors David V. Hansen, PhD, a postdoctoral fellow, and Jan H. Lui, a graduate student in the Kriegstein lab, examined the OSVZ, using new labeling and tracking techniques to follow individual cells and their progeny over time in cultured tissue slices from fetal cortex tissue that had been donated for researc
In the current study, lead authors David V. Hansen, PhD, a postdoctoral fellow, and Jan H. Lui, a graduate student
in the Kriegstein lab, examined the OSVZ, using new labeling and tracking techniques to follow individual cells and their progeny over time in cultured tissue slices from fetal cortex tissue that had been donated for researc
in the Kriegstein lab, examined the OSVZ, using new labeling and tracking techniques to follow
individual cells and their progeny over time
in cultured tissue slices from fetal cortex tissue that had been donated for researc
in cultured
tissue slices from fetal cortex
tissue that had been donated for research.
We are using a new technique, called single
cell RNA sequencing, to isolate thousands of single neurons from human brain
tissue, study all the genes that are expressed
in each
individual cell, and make
cell - to -
cell comparisons between normal, early stage and late stage AD.
In contrast to germline variants, somatic variants are not propagated to the whole individual but to a subpopulation of cells in the body, with the final consequence that adult human tissues are a mosaic of genetically different cell
In contrast to germline variants, somatic variants are not propagated to the whole
individual but to a subpopulation of
cells in the body, with the final consequence that adult human tissues are a mosaic of genetically different cell
in the body, with the final consequence that adult human
tissues are a mosaic of genetically different
cells.
Cell culture studies involve removing
tissue (or even
individual cells) from a plant or animal and growing them
in a laboratory environment.
Different trials are using stromal
cells isolated and transplanted
in different ways with the aim to dampen the
individual's immune response and / or enhance repair of the damaged
tissue, but the research has yet to reveal the role these
cells play
in immunomodulation.
As a person gets older and the growth hormone production slows down, and
individual notice and begin experiencing certain symptoms like the degeneration of
cells and
tissues, poor functioning of certain organs
in the body, a slow rate of conversion of body fat for energy and a decrease of muscle development, and low energy.
In young healthy individuals, the role played by oxygen radicals and H2O2 in enhancing insulin signaling is helpful, and so important that almost all cells and tissues contain special enzymes that produce H2O2, and O2 - at a well - regulated rat
In young healthy
individuals, the role played by oxygen radicals and H2O2
in enhancing insulin signaling is helpful, and so important that almost all cells and tissues contain special enzymes that produce H2O2, and O2 - at a well - regulated rat
in enhancing insulin signaling is helpful, and so important that almost all
cells and
tissues contain special enzymes that produce H2O2, and O2 - at a well - regulated rate.
Even
in healthy
individuals, prolonged high levels of insulin caused by consuming free sugars and highly processed starches, has been shown to increase inflammation
in the body.2 And inflammation
in the body can also trigger depression.3 By reducing or eliminating free sugars
in your diet, you'll be able to reduce inflammation throughout your body's
cells and
tissues, 4 and ward off unsavory diseases.
Bioelectrical impedance vector analysis (BIVA) expresses
tissue hydration status and body
cell mass solely while considering the impedance vector relative to a population of healthy
individuals (24); this was a valid method for detecting changes
in hydration (classified as under -, normal or overhydration) and body fluid volume changes (25).
There are many types of connective
tissue and these two amino acids feature prominently
in most of them, from the cartilage that forms our joints to the extracellular matrix that acts as a scaffold for the
cells in our
individual organs, muscles, arteries etc..
The Wilderness Kitten also feature 5 strains of various beneficial bacteria that help
in promoting optimum digestive health so that all of the nutrients present
in your kitty formula will be absorbed and utilized by
individual cells and
tissues.
The therapeutic laser provides energy to stimulate
individual cells deep within
tissues, giving the
cells more energy to optimize its own role
in the body's natural healing process.