Highly parallel genome - wide expression profiling of
individual cells using nanoliter droplets.
«A very futuristic view is that maybe we will be able to extract energy from
individual cells using similar designs,» she says.
Not exact matches
Regarding intensity, a study published in PLOS ONE found that workout intensity was not affected for
individuals talking on the phone, compared to those not
using a
cell phone, but when it came to texting, workout intensity was significantly lower.
Scientists can create tissue to see how it will respond to chemicals or medicines, and an
individual's own
cells can be
used to create a replica tissue sample for a more accurate forecast of how that person's body will react.
The United Nations Development Programme (UNDP) is planning a pilot project to test a system that allows
individuals to invest in solar energy - generating
cells and effectively receive rent from consumers that
use the hardware.
Structural constraints in the telecom industry still limit the
use of
cell phones as a mass communications tool in U.S. politics, but
individual Obama supporters and organizers of course
used text messaging, video and voice calls extensively in their own personal outreach.
The team created microscopic wounds in the pupae's epithelial layer
using a laser that can be focused down to a point small enough to punch microscopic holes in
individual cells (less than a millionth of a meter).
A new research tool
using light allows scientists to watch
individual brain
cells react in real time.
There, a team led by Uma Ramakrishnan, known for
using DNA to trace the heritage of ancient South Asians, set to work identifying
individual tigers from intestinal
cells in the excrement.
Unlike conventional chemotherapies and radiation that indiscriminately eradicate fast - growing tissues and ravage people's bodies with side effects, new therapies specifically target tumors
using tailored
cells from
individual patients.
Using the same adaptive optics principles that let astronomers see distant objects with such instruments as the Keck Telescope, researchers have created a new device for ophthalmologists to see the eye's retina at the
individual cell level.
«It would be really nice to derive and compare iPS
cells and
cells made
using the Dolly technique from the same
individual to see which were most normal,» says Robin Lovell - Badge of the National Institute for Medical Research in London.
In animals, implanted electrodes were
used to measure the activity of
individual grid
cells directly, but this is not a practical option in humans.
Richard Jones, M.D., professor and director of the Bone Marrow Transplant Program at Johns Hopkins, developed a now commonly
used assay to study ALDH levels in
individual cells.
Living
cells are micrometer - scale units capable of replication, growth, chemical synthesis, and movement
using technologies operating on
individual molecules at the nanometer scale.
They
used this novel simulation approach to build a model of a sperm
cell that demonstrates cellular movement from
individual dynein protein molecules in the tail all the way up to the whole
cell, allowing them to observe how changes at the atomic level are reflected in larger - scale structures.
Existing European patents involving embryonic stem
cells — most of which were issued in the United Kingdom — will not be invalidated immediately, but lawsuits challenging
individual patents will
use the ruling as guidance.
The presented approach
uses untethered magnetic micro-robotic coding for precise construction of
individual cell - encapsulating hydrogels (such as
cell blocks).
Using this biosensor in highly invasive breast cancer
cells taken from rodents and humans, the Einstein team discovered that when an
individual invadopodium forms and is actively degrading the ECM, its Rac1 levels are low; on the other hand, elevated Rac1 levels coincide with the invadopodium's disappearance.
«We are really just beginning to explore the many possibilities in
using this micro-robotic technique to manipulate
individual cells or
cell - encapsulating building blocks.»
Using a technique known as single -
cell RNA sequencing, the team explored more than 65,000
individual cells that exist under normal or inflammatory conditions, looking for genes that were more active in one state or subpopulation versus another.
«The next step of progress is to
use this knowledge to decipher what potential impact the genetic variants can have on the health of
individuals, when we conduct health - related research,» added Professor Michael Pepper, Unit Director of the South African Medical Research Council's (SAMRC) Stem
Cell Research and Therapy Unit, Faculty of Health Sciences at the University of Pretoria.
Using a standard inverted microscope, researchers can then lift the desired
cells and transfer them into
individual sample tubes or microtiter wells.
The researchers
used a technique called laser scanning photostimulation to map the connections between
individual subplate neuron
cells in the brains of the mouse pups.
To trace
individual neurons, Jeff Lichtman of Harvard
uses engineered mice whose DNA includes jellyfish genes so that the
cells contain fluorescent proteins.
Another key finding of the research was that the impact of vitamin D on inflammatory disease can not be predicted
using cells from healthy
individuals or even from the blood of patients with inflammation as
cells from the disease tissue are very different.
Researchers are
using the sea hare model to learn about
individual cells function, discover the chemical pathways controlling various brain activities and to study how memories are processed and stored.
In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful
use of somatic
cell nuclear transfer, or SCNT, to produce human embryonic stem
cells from an
individual's skin
cell.
sNuc - Seq bypassed those problems by
using individual nuclei extracted from
cells as a starting point instead.
Although the new JNCI study did not analyze
individual cell phone usage — preferring instead to take a broader look at the population at large — other research has examined subgroups of
cell phone users to try to discern different trends among more frequent
use.
Building on the newly - published pilot study, the team will conduct experiments
using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of
individual odour - detecting
cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of malaria - infected Anopheles gambiae s.s. females to human odours.
When a standard hearing test was performed on these hearing - impaired
individuals, the responses of their auditory sensory
cells and neurons, although normal to begin with, gradually worsened as the test went on as a result of the sounds
used.
His research largely focuses on new means to incorporate imaging methods to view
cells of brain tumors with a hand held instrument that a neurosurgeon can
use to visualize the
individual cells during the progress of the operation.
Collins said that because Hydra is such a simple animal and because it is able to regenerate after complete dissociation into
individual cells, it offers researchers the opportunity to
use similar techniques as the ones employed in their experiments to examine how an organism develops from an unstructured group of
cells into a complex body plan.
In the past year, biologists have been
using the natural form of GFP to track the production of
individual proteins or the activity of particular genes in living
cells.
Linked to green fluorescent protein (GFP), the biosensors can be
used to trigger
individual cells to give off visible fluorescence in a rate directly proportional to how well they are able to produce a desired chemical commodity.
The Epigenetics Research group
used these
cells to perform genome - wide profiling across more than 20,000
individual genes in these patients.
Lei and Spradling
used a technique that allows
individual cells and their progeny within a living animal to be followed over time by marking the
cells with a new gene.
The research team first
used the blood of healthy
individuals, spiking some of the blood with living breast cancer
cells to see if the NanoFlares could detect them.
Prof Tony Green, an author from the Wellcome Trust - MRC Stem
Cell Institute and Cambridge University, said: «The SC3 tool was able to
use patterns of gene expression to distinguish, within an
individual cancer, subclones that carried different mutations.
Using single -
cell RNA sequencing, the team was able to profile molecular features and metabolic activity of
individual beta
cells to determine how dividing beta
cells differ from non-dividing
cells.
These
individual transcriptomes can be
used to define
cell types and to understand the functions of healthy and diseased
cells in the human body.
Split Pool Ligation - based Transcriptome sequencing (SPLiT - seq) is a scalable technique for characterizing RNA in
individual cells that can be
used to identify the various
cell types found in the brain and other tissues.
The team first
used the tried - and - true method of growing yeast in Petri dishes and painstakingly counting how many times an
individual yeast
cell produced a daughter
cell.
In brain research, these tools have been
used successfully to regulate
individual nerve
cells in millisecond time scale
using light instead of electrical stimulus.
«
Using high - power microscopy, we can watch
individual cells and follow along with how they replicate in real time,» says Lenhart.
Using live imaging in zebrafish to track oligodendrocytes in real time, researchers reporting in the June 24 issue of the
Cell Press journal Developmental
Cell discovered that
individual oligodendrocytes coat neurons with myelin for only five hours after they are born.
Part of the answer is simply that the most commonly
used DNA probes tell whether or not a given sequence is present, not how many times it appears in an
individual cell.
«Nano - sized mesoporous silica particles have already been established as useful for manipulating
individual cells from the inside, but this is the first time that larger particles, in the micron - sized range, are
used to create a 3D in vivo scaffold that can recruit and attract tens of millions of immune
cells,» said co-lead author Jaeyun Kim, Ph.D., an Assistant Professor of Chemical Engineering at Sungkyunkwan University and a former Wyss Institute Postdoctoral Fellow.
The assay
uses time - lapse microscopy to monitor
individual yeast
cells undergoing a small number of divisions to form microcolonies.