Sentences with phrase «individual diseases of aging»

Not exact matches

In the area of living individuals and genetic intervention are questions of patient responsibility and the sharing of genetic information: If a doctor could know that you will contract Huntington's disease at age 40 or Alzheimer's disease at age 60, at what age would you want to be told?

Statistics from the U.S. Centers for Disease Control and Prevention suggest that roughly three out of four individuals with the virus fall within that age range; about the same percentage of those infected who die as a result of infection were born within that span.

While sexually transmitted diseases (STDs) affect individuals of all ages, STDs take a particularly heavy toll on young people.

Researchers studied HIV positive individuals, ages 30 to 50 years, who did not have osteoporosis, had no history of immunological disease other than HIV, had serum vitamin D and calcium levels within the normal range, and normal CBC and blood chemistry profiles.

Bress and the researchers analyzed data from individuals who met SPRINT eligibility: they were of age 50 or older, at high risk of cardiovascular disease and without a history of diabetes or stroke.

It also remains hard at work on a project called IDEAL — Insights into the Determinants of Exceptional Aging and Longevity — that hopes to understand «exceptional agers,» individuals 80 and older who are healthy and disease - free.

Coeliac disease or celiac disease is an autoimmune disorder of the small bowel that occurs in genetically predisposed individuals in all age groups after early infancy.

The authors anticipate that health care providers will use the early - detection biomarkers to test for their presence and levels in blood from pancreatic cancer patients and blood drawn from individuals with a high risk of developing pancreatic cancer, including those who have a first - degree relative with pancreatic cancer, are genetically predisposed to the disease, or who had a sudden onset of diabetes after the age of 50.

«There's only so much we can gain in terms of disease - free longevity by curing individual diseases like cancer and Alzheimer's one at a time, but if we can address the issue of aging, then we could potentially delay and diminish them all at once.»

The recent growth is driven, experts say, by aging populations and increased life expectancy in the developed world; combination products that couple a medical device with a drug, the device usually acting as a drug - delivery vehicle; miniaturization (via nanotechnology), making medical devices less invasive; and the use of molecular diagnostics to customize therapeutic regimens and to assess individual disease risk.

In patients with chronic cerebrovascular disease and comorbidities, a shortened telomere G - tail length was associated with age and Framingham risk score, which is an algorithm used to estimate the 10 - year cardiovascular risk of an individual.

A report from the United Nations Scientific Committee on the Effects of Atomic Radiation found that 6,000 individuals who were under the age of 18 in Ukraine, Belarus or Russia at the time of the disaster had by 2006 contracted thyroid cancer, «a substantial fraction» of whom likely contracted the disease due to radiation exposure.

The chronic state of low - level inflammation seen in many elderly individuals (sometimes called «inflamm - aging»), is associated with diseases such as cardiovascular disease and dementia, as well as susceptibility to infections, especially pneumonia.

To do this, the research team enrolled 65 healthy volunteers aged 18 to 50 years in the human challenge study — a type of research study in which individuals are exposed to disease - causing pathogens under carefully controlled conditions.

There were 22,278 individuals over the age of 6 who participated in the surveys who underwent blood tests for celiac for whom information about prior diagnosis of celiac disease and adherence to a gluten - free diet was collected in a direct interview.

In the most comprehensive study ever on the impact of smoking on cardiovascular disease in older people, epidemiologist Dr. Ute Mons from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) analyzed 25 individual studies, compiling data from over half a million individuals age 60 and older.

Tali Sharot, a University College London neurology researcher, and her colleagues asked 19 individuals between the ages of 19 and 27 to estimate their odds of experiencing 80 unfavorable events, such as contracting various diseases or being the victim of a crime.

While increased telomerase activity could bring youth to aging cells and cure premature aging - like diseases, too much of a good thing can be damaging for the individual.

«Age and gender influence risk for certain peripheral vascular diseases: Findings drawn from large - scale study of 3.6 million screened individuals provided by life line screening.»

They have also begun examining whether these individuals are resistant to other aging - related killers, including cardiovascular disease and Alzheimer's disease — both linked to dysfunctional production or metabolism of insulin and IGF - 1.

In a long - term, large - scale population - based study of individuals aged 55 years or older in the general population researchers found that those diagnosed with mild cognitive impairment (MCI) had a four-fold increased risk of developing dementia or Alzheimer's disease (AD) compared to cognitively healthy individuals.

Caloric restriction became something of a fad two decades ago, when a few individuals set out to cut their calories by 30 percent to slow the diseases of aging, but the Wisconsin and NIA studies have a much broader focus.

Comparing the magnitude and characteristics of WNV - specific CD4 + T cell response in individuals of similar ages with either neuroinvasive disease or asymptomatic infection, the researchers found that, independent of age, individuals with neuroinvasive disease had higher numbers of WNV - specific CD4 + T cells.

The frequency of the risk C variant in Spanish people over the age of one hundred was 47.0 %, lower than in healthy people that were taken as a control sample in the study (52.9 %) and individuals with cardiovascular disease (55.1 %).

«We believe the aging of the U.S. population is likely driving the increase in MCC, as this cancer is much more prevalent in older individuals,» Dr. Nghiem says, adding that weakened immunity in this population may play a role in the disease.

Individuals who carry this ε4 variant of APOE are at increased risk for developing Alzheimer's disease, early age of Alzheimer's disease onset, and more rapid progression of Alzheimer's disease symptoms.

Approximately half of individuals with autosomal dominant polycystic kidney disease eventually will require dialysis or kidney transplant by age 60.

In order to work out which is the chicken and which is the egg, i.e. whether the epigenetic changes are a consequence of the disease or if the disease is a result of the changes, the researchers also investigated whether healthy individuals had epigenetic changes caused by age, BMI and raised blood sugar levels.

The research «may provide useful information to help understand some age - related diseases and physiological phenomenon specific to women or men, and inspire new ideas for prevention and diagnosis of the diseases by considering the individual conditions based primarily on the salivary analysis,» the scientists state.

They compared 9,405 people living in Sweden who were diagnosed with inflammatory bowel disease before they were 18 years of age with 92,870 healthy individuals (reference individuals) matched for sex, age, birth year, and place of residence.

Globorisk measures cardiovascular risk in individuals aged 40 or older by factoring in the person's smoking status, blood pressure, diabetes status, and total cholesterol level, whilst adjusting for the effects of sex and age on cardiovascular disease between countries.

Frequent exposure to ultraviolet (UV) rays for individuals under the age of 35 increases the risk of developing melanoma — the most aggressive and deadliest form of skin cancer — by 75 percent, according to the Centers for Disease Control and Prevention.

In its twenty years of operation, the NRSA program has made it possible for many thousands of talented individuals in the basic biomedical, behavioral, and clinical sciences to sharpen their research skills and to apply those skills to topics of special concern to the nation, such as aging, hypertension, the genetic basis of disease, acquired immune deficiency syndrome (AIDS), cancer, environmental toxicology, nutrition and health, and substance abuse.

For most diseases, an individual's risk arises from a combination of genes, environment, age, and other factors.

His research is based on the concept that normal brain aging and the pathogeneses of sporadic neurological diseases are not a consequence of a few single or «disease - specific «factors alone, rather they are driven by holistic events that include one's individual genetic and epigenetic condition, progression of aging, and lifestyle.

Vaccinating older individuals is problematic, as the effectiveness of most vaccines decrease with age, with maximal responses often as low as 30 % in the over 70s.5 Nevertheless, vaccination programmes demonstrate the ability to reduce disease burden in the elderly as well as offering a tool to observe immune responses in vivo in humans.

Lastly, increased systemic inflammation seen during ageing is also apparent in chronic infections such HIV or cytomegalovirus, 10,15 obesity7 and individuals enduring chronic psychological stress.16 Similarly, the main features of immunosenescence are apparent in many of these conditions, including decreased antibody responses, increased infections, malignancies and also incidences of inflammatory associated disorders such as cardiovascular disease.7, 10,15,16 Inflammation and premature immunosenescence are, therefore, prevalent features of many common conditions of modern life, such as obesity and stress, and could have negative health consequences for large proportions of society well before old age is reached.

«We are delighted to announce the award of Recovery Act funds to many dedicated, hardworking scientists committed to advancing scientific discovery into Alzheimer's disease and cognitive impairment,» said NIA Director Richard J. Hodes, M.D. «Over the next two years, the recipients will use this unprecedented boost in research funds to help reach our ultimate goal of understanding age - related cognitive decline and reducing the individual and societal burden of this devastating disease.»

Although encountered at any age, SSS is primarily a disease of the elderly and is often secondary to other cardiac disorders when diagnosed in younger individuals.

UNITY Biotechnology Launches with a Focus on Preventing and Reversing Diseases of Aging February 03, 2016 SAN FRANCISCO --(BUSINESS WIRE)-- UNITY Biotechnology today announced that it is developing medicines to treat and eliminate age - related diseases and increase healthspan, or the amount of time an individual lives in good health.

The role of αCaMKII autophosphorylation in the establishment of alcohol addiction Alanna Easton, King's College, UK Novel age - dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research Karienn Montgomery, University of Florida, USA Microsatellite regions upstream of the vole Avpr1a gene contribute to both individual and species differences in receptor expression Zoe Donaldson, Columbia University, USA Per Genes and Addiction Stephanie Perreau - Lenz, Central Institute of Mental Health, Germany

Genomic sequencing of healthy individuals could grow to resemble current population - based preventative screening measures, such as newborn screening or the use of colonoscopy after age 50, which have been integrated into clinical practice to identify uncommon diseases.

As a result, the disease generates age - like conditions: It wipes out affected individuals» bone marrow, predisposes them to a variety of human cancers, and gives them splotchy skin, ratty fingernails, and prematurely gray hair.

This research has found clear signs of reduced cardiovascular disease risk, and perhaps slower aging, in these individuals.

To investigate the possible protective effects of coffee and tea, researchers examined data on more than 2,400 Dutch individuals age 45 or older who did not have liver disease.

The benefit seemed to be particularly pronounced in individuals with the apolipoprotein E-e4 allele, a genetic marker associated with late - onset Alzheimer's, which usually happens after the age of 65, and is the most common type of the disease

A study which monitored the thinking and memory processes of people over the age of 65 has found that all individuals with higher caffeine levels had avoided the start of Alzheimer's disease in the 2 to 4 years of the study follow up.

The goal of anti-aging medicine is to use recent scientific advances and treatment modalities to promote «Healthy Aging» and to prolong the healthspan of an individual — so that more of their years are spent in good health and few, if any, are spent with disease.

Adjusted Hazard Ratio of Cardiovascular Disease Mortality According to Usual Percentage of Calories From Added Sugar Adjusting for Individual Components of Healthy Eating Index Among US Adults Aged > 20 Years — NHANES Linked Mortality Files, 1988 - 2006

Our vaccination recommendations are tailored to each individual pet and depend on factors such as species, age, risk of exposure, history of reaction, severity of disease, and efficacy of available vaccines.