Sentences with phrase «individual genes in the mouse»

By knocking out individual genes in the mouse, they can systematically discover any that have a crucial biological role, or are linked with disease.

Not exact matches

The ability to edit a single, carefully targeted gene in each organism means that individual members don't need to be the perfect genetic clones currently filling mouse and fly labs.

In this mouse model, mutations in Kras and p53 genes resulted in the formation of individual tumor cell populations that were labeled with different colorIn this mouse model, mutations in Kras and p53 genes resulted in the formation of individual tumor cell populations that were labeled with different colorin Kras and p53 genes resulted in the formation of individual tumor cell populations that were labeled with different colorin the formation of individual tumor cell populations that were labeled with different colors.

Using novel technologies developed at HMS, the team looked at how a single sensory experience affects gene expression in the brain by analyzing more than 114,000 individual cells in the mouse visual cortex before and after exposure to light.

It would be great if we could just go in and quickly manipulate individual mouse genes and study their function in health and disease, but, until recently, it just wasn't that easy.

Such information will help reveal how all traits are affected by deleting a given gene in an individual mouse.

This Vignette animates the creation of a data driven classification of the cell types in the mouse visual cortex based on the individual cells» gene expression.

The role of αCaMKII autophosphorylation in the establishment of alcohol addiction Alanna Easton, King's College, UK Novel age - dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research Karienn Montgomery, University of Florida, USA Microsatellite regions upstream of the vole Avpr1a gene contribute to both individual and species differences in receptor expression Zoe Donaldson, Columbia University, USA Per Genes and Addiction Stephanie Perreau - Lenz, Central Institute of Mental Health, Germany

Recent studies in mice suggested that antibodies produced by old individuals may be encoded by distinct immunoglobulin (Ig) genes and that the somatic hypermutation process in these individuals is compromised.

Besides information gathered to answer specific experimental questions, as determined by the interests of individual partners [35]--[41], the collective data offered the opportunity to search for coordinated gene expression patterns in a systematic exploration of the mouse ES transcriptome under a battery of different experimental settings, thus minimizing possible site - specific artifacts.

The Supreme Court of Canada determined in 2002 that one could not patent a higher life form (an altered mouse having cancer genes), however individual cells were patentable (Harvard College v CIPO 2002 SCC 76).