Not exact matches
Building on the newly - published pilot study, the team will conduct experiments using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of
individual odour - detecting cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of
malaria - infected Anopheles gambiae s.s. females to
human odours.
Researchers here are cataloguing what makes cancer cells dangerous down at the level of
individual genetic changes, how and why pathogens like
malaria evolve to be more (or less) harmful and how
humans adapt to those changes.
By analyzing genome sequence data from
human populations, including 1269
individuals from sub-Saharan Africa, we identify a diverse array of large copy number variants affecting the host invasion receptor genes GYPA and GYPB We find that a nearby association with severe
malaria is explained by a complex structural rearrangement involving the loss of GYPB and gain of two GYPB - A hybrid genes, which encode a serologically distinct blood group antigen known as Dantu.
The association of the Duffy blood group (FY) with P. vivax
human malaria has been well - documented, where Duffy - negative
individuals are naturally resistant to invasion by this parasite [2].