Sentences with phrase «individual nucleotide sequence»
Silence's specific siRNA molecules exhibit unique structural features which, irrespective of their individual nucleotide sequence, bar third parties from commercialising this type of molecule.
http://www.silence-therapeutics.com/ Not exact matches
We present a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals.
They reveal 341 fixed substitutions (35 nonsynonymous, 173 synonymous, and 133 noncoding) between the 2014 EBOV and all previously published EBOV sequences, with an additional 55 single - nucleotide polymorphisms (SNPs; 15 nonsynonymous, 25 synonymous, and 15 noncoding), fixed within individual patients, within the West African outbreak.
In the 7 May 2010 issue of Science, an international team of researchers presents the draft sequence of the Neandertal genome composed of over 3 billion nucleotides from three individuals.
Bustamante and Poznik obtained highly accurate sequencing results over a length of about 10 megabases of Y chromosome DNA (or 10 million nucleotides) for each of the 69 individuals.
However, based on data now available, we see that the sequence of the 3 billion nucleotides in any individual genome is unique in comparison with the sequence of another individual's genome, while the degree of sequence similarity between the 3 billion nucleotides in any two genomes is remarkably high.
Then, in 2010, Pääbo and colleagues published a draft sequence of the Neanderthal's nuclear genome — 4 billion nucleotides — based on three individuals.
Called the stairway plot, it models the frequency of single nucleotide polymorphisms (SNPs) in whole genome sequences of hundreds of individuals.
To generate whole - genome and individual gene nucleotide phylogeny trees, all 95 fully sequenced unique adenovirus genomes were first downloaded from GenBank.
The term «single - nucleotide polymorphism» (SNP) refers to a single base change in DNA sequence between two individuals.
Scott D. Collins, Ph.D., University of Maine, Orono $ 850,000 (2 years) «High - speed Nanopore Gene Sequencing» Skilled in silicon fabrication methods, this group will try to fabricate a nanopore with tiny electrodes and built - in circuits that will be used in experiments that attempt to measure differences in the electron tunneling of individual nucleotides in DNA molecules.
A single DNA sequence is formed from a chain of four nucleotide bases and if some individuals in a population do not carry the same nucleotide at a specific position in the sequence, the variation is classified as an SNP.
After sequence read quality and damage filtering (Supplementary Fig. 4), we called per - individual consensus sequences for nucleotide positions covered by a minimum of two independent reads.
The resulting consensus sequences averaged 16,231 ± 455 bp, or 98.1 % of the complete mitochondrial genome, with the average number of reads per nucleotide position (fold - sequence coverage) ranging from 7.4 × to 117 × among the 9 individuals (Supplementary Data 1).
At the highest level of resolution, the user can inspect the nucleotide sequence of individual genes.