Sentences with phrase «individual older mice»

The GDF11 protein commonly found in the blood of young mice (the same protein that enhanced neurogenesis in aged mice) and placed in individual older mice was thought to have the same reversal effect on hypertrophy; however, more recent research suggests another molecule besides GDF11 may be at work.

Not exact matches

(C) Human islets, isolated postmortem from nondiabetic individuals, were treated with 1 % islet homogenate from old Tg - hIAPP mice, WT control islet homogenates, or old Tg - hIAPP immunodepleted using a cocktail of sequence and conformational antibodies.

Male or female (5 - 6 wks old) wild type and genetically modified mice (as required for individual investigator's protocols) will be fed a high fat high sucrose diet (from Research Diets ranging in fat from 45 - 58 % of calories as fat, 26 - 39 % carbohydrate (sucrose) and 16 % protein or control diets (10 % fat, 73 % carbohydrate, 16.4 % protein or rodent chow) for up to 16 weeks.

Recent studies in mice suggested that antibodies produced by old individuals may be encoded by distinct immunoglobulin (Ig) genes and that the somatic hypermutation process in these individuals is compromised.

In FTD, any benefit of exercise on progranulin levels would need to occur in haploinsufficient individuals and at older ages, so we considered it important to examine exercise in Grn + / − mice at a symptomatic age.

Maybe us younger individuals won't notice the hours of strain, but older people and those with certain disabilities may be reluctant to twist there wrist around a mouse for hours a day.