Sentences with phrase «individual tumor types»
«The additional information we can now derive from tumor biomarkers such as E-cadherin, nm23 and microvessel counts should begin to allow us to tailor therapy according to individual tumor types,» added Samuel Hellman, MD, A.N. Pritzker Distinguished Service Professor of radiation and cellular oncology at the University of Chicago and co-author of the paper.
http://www.uchospitals.edu/ Not exact matches
«If we can define which types of mutations and changes are the critical events driving tumor growth, we will be better equipped to identify the most appropriate treatments for individual cancers.»
To illuminate the process, the Yale team sequenced normal, primary, and metastatic tumor tissue from multiple individuals, including subjects with a range of cancer types.
The research also showed that gene expression patterns of individual tumors varied considerably, and could exceed the variation observed between different cancer types.
Dr. Eng and team create scoring system to facilitate identifying individuals to be referred to PTEN gene testing Researchers have discovered a method for more precise identification of individuals who should undergo testing for genetic mutations of the tumor suppressor gene PTEN, which associates with a variety of conditions including several types of cancers.
Around 700 individual tumors representing 17 major cancer types were characterized in the studies above.
Krogan believes that mutations in a few key networks of genes cause diseases like cancer, even though the individual genes that are mutated in tumors vary between different people and different types of cancer.
My studies of cancer genomes have led to characterization of multiple pediatric and adult tumor types, to development of methods that identify and characterize changes in genomic heterogeneity, to defining acquired resistance mechanisms to targeted therapies and to designing novel, personalized vaccines for individual patients.
The ViroChip microarray [2], [3], [44], [45] was used to screen RNA samples isolated from prostate tumors collected prospectively from 39 individuals, of which 16 individuals were genotyped as harboring the R462Q RNAse L mutation (QQ), 10 individuals were heterozygous cases (RQ), and 13 were wild - type cases (RR).
In addition to cryoablation, she has recently obtained a microwave ablation unit, allowing the hospital to offer two different types of minimally invasive tumor ablation, according to the best choice for the individual patient and disease.
The total number of treatments depends on the type and size of the tumor as well as individual risk factors.
In rare cases a tumor called fibrosarcoma may develop at the injection site, however, this has been found to develop in only specific individuals who are genetically predisposed to form these tumors secondary to any type of infection or inflammation.