Sentences with phrase «induce cell injury»

Not exact matches

«It appears that injury itself can induce fibroblasts to change into endothelial cells so the heart heals better.

To find out whether increasing cell self - destruction in the lungs could actually decrease cell death — and ultimately prevent lung injury — Bhandari and his research team targeted a regulator protein called RPTOR, which when inhibited, is responsible for inducing autophagy.

Retinal cell death can be induced by phagocytic immune cells that infiltrate the tissue in response to injury or infection, but the molecular signals that trigger phagocyte invasion are largely unknown.

Instead, uPA appears to help brain cells recover from the injuries induced by loss of blood flow.

Impact of bone marrow - derived mesenchymal stem cells on remodeling the lung injury induced by lipopolysaccharides in mice Mouchira M Mohi El - Din, Laila A Rashed, Mohi A Mahmoud Haridy, Atef Mohamed Khalil, Mohamed A Mohamed Albadry.

A vascular injury model using focal heat - induced activation of endothelial cells.

SIH — a novel lipophilic iron chelator — protects H9c2 cardiomyoblasts from oxidative stress - induced mitochondrial injury and cell death.

The findings, which were published today in Cell, also demonstrated that Moderna's Zika mRNA vaccine protected the placenta and fetus from Zika virus - induced injury.

Co-precipitating of fibrotic lesions as demonstrated by collagen expression in acinar cells may be attributed to defence mechanism against inflammatory cytokine - induced pancreatic injury and inflammation [26]; interestingly, the collagen expression was restored when pancreatic inflammation was relieved [46].

While previous studies had demonstrated a synergistic effect of BMP and LIF on the astrocytic differentiation of human neural stem cells [15], it remains unclear whether BMP and LIF induce distinct types of astrocytes and if so, what the functional properties of these astrocytes may be with respect to repairing CNS injuries.

Making use of cell and animal models, my laboratory group addresses some of the fundamental questions of how ethanol exposure injures the liver, with a goal ofidentifying the individual targets of ethanol - induced injury and the specific responses of the key cell types within the liver, as well as the integrated, organismal response to this ethanol - induced injury.

Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol - induced liver injury in mice.

In particular, we are interested in the contributions of the innate immune system, including the resident macrophage in the liver (Kupffer cells) and the complement pathway, in the initiation and progression of ethanol - induced liver injury.

Gadd45b plays a role in cell cycle arrest, and it is a positive mediator in Fas - induced apoptosis when a DNA injury appeared in nonneoplasic cells [28].

Cardiac injury induces the loss of viable heart muscle cells, cardiomyocytes.

These studies clearly provided evidence that GABA had a considerable gastroprotective effect on ethanol - induced gastric mucosal injury and gastric epithelial cells injury.

Excitotoxicity is a pathological process where glutamic and aspartic acid cause an over-activation of your nerve cell receptors, which can lead to calcium - induced nerve and brain injury.

Because FHV - 1 can induce tissue injury directly as a result of viral cytolysis or indirectly through immunopathologic processes mediated by inflammatory cells, treatment of FHV - 1 keratoconjunctivitis involves: 1) prevention of viral replication; 2) immunomodulation; and, 3) prevention of secondary bacterial infection.