Now one team, reporting in the journal ACS Chemical Neuroscience, has identified how amyloid beta, the protein fragment strongly associated with Alzheimer's disease, can
induce cellular changes that might lead to Parkinson's.
Not exact matches
«But we know that the expression of these factors is
inducing changes in the epigenome, and those are leading to benefits at the
cellular and organismal level.»
The new study shows that despite these outliers, antibiotics don't promote resistance spread by
inducing global
changes at the
cellular level.
At a
cellular and molecular level, no one really knows how the vagus nerve detects different physiological stimuli, from the stretch of the stomach after a meal to toxins that
induce nausea to
changes in blood pressure.
It was originally thought that ATRA was successfully treating APL by
inducing cell differentiation, causing cancer cells to
change into normal cells by activating the
cellular retinoic acid receptors.
In conclusion, the proteomic approach revealed that
cellular stretching
induced specific phosphorylation
changes in chondrosarcoma cells.
The researchers used a novel method called thermal proteome profiling to detect
cellular changes induced by palbociclib.
This technology is based on observing drug
induced changes in the thermal stability of
cellular proteins.
Research The acute phase response and soman -
induced status epilepticus: temporal, regional and
cellular changes in rat brain cytokine concentrations.
We found significant differences in overall
cellular composition between pre - and post-mortem blood samples (p < 0.001), the most notable
changes induced by death being an increase in resting NK cells and CD8 T - cells, and a substantial reduction in neutrophils (Fig. 7a).
''... we hypothesize that repeated stress - related allostatic overload may affect brain function at three basic levels: (a) at the
cellular level, it may compromise proteostasis (e.g. tau protein), organelles homeostasis, and
induce epigenetic
changes in neuronal DNA; (b) at the tissue level it may affect intracellular communication (synaptic contacts), number of cells (reduction of neuronal density), composition of the extracellular matrix (accumulation of amyloid plaques), and neuroinflammation; (c) at the systemic levels it may alter the brain's regulation of behavior (cognitive decline).
Modern lifestyles and environments have
induced changes in
cellular function in unimaginable ways, often to the detriment of the human body.
It remains to be examined by using the neonatal novelty exposure procedure whether the early stimulation -
induced changes in neuroendocrine and associated
cellular / molecular measures associated with handled rats (38) can be preserved despite a lack of greater maternal care.