Sentences with phrase «induce cellular damages»

Reactive oxygen species (ROS) induce cellular damages at different levels (proteins, DNA, and lipids) which increase the body susceptibility to noxious injuries with the final result to accelerate aging and decrease lifespan.

One of his earliest studies revealed that alternate - day feeding made the rats» brains resistant to toxins that induce cellular damage akin to the kind cells endure as they age.

Not exact matches

Based on the previous evidences, it rusults important to maintain cellular NAD + availability especially in mitochondria when stresses induce a major consumption of NAD + and ATP and prone the organism more susceptible to ROS damages.

Ionizing radiation is a potent DNA damaging agent that interacts with cellular DNA and induces lesions in the irradiated cells and prevents cell proliferation and induces cell death by apoptosis or necrosis depending on the radiation dose.

Despite the protection offered by the cellular environment, the integrity of DNA is continuously challenged by a variety of endogenous and exogenous agents (e.g. ultraviolet light, cigarette smoke, environmental pollution, oxidative damage, etc...) that cause DNA lesions, interfering with proper cellular functions, such as transcription, inducing premature cellular death and finally premature ageing and organs dysfunctions.

In response to cellular stress such as DNA damage, oncogene activation, transcriptional inhibition, and hypoxia, tumor suppressor p53 is activated and expressed, and acts as a transcription factor to induce its target genes [1], thereby playing a central role in the regulation of DNA repair, cell cycle, apoptosis, senescence, and angiogenesis [2 - 4].

You need to execute the exercise with proper form in order to target the muscle you are training and keep it enough time under tension to induce the damage at a cellular level, that is actually the starting point in the muscle growth process.

One reason might be the role of fat in inducing oxidative stress and creating free radicals, which are highly reactive atoms and molecules that damage DNA and cellular walls, ultimately killing heart muscle cells.

But up - regulating cellular immunity can induce tissue damage and excessive inflammation in the long - run.