Sentences with phrase «induce high gene»

It can efficiently introduce DNA into a cell to be incorporated into its genetic make - up, i.e. induce high gene expression level, especially in both human and mouse breast cancer cell lines, and mouse breast cancer model.

Not exact matches

When normal and gene - altered mice got the high - fat diet along with varying levels of doxycycline, to induce GLP1 release, the normal mice grew fat and mice expressing GLP1 showed less weight gain.

When normal and gene - altered mice ate the high - fat diet — along with varying levels of doxycycline to induce GLP1 release — mice expressing GLP1 (left) gained less weight gain while normal mice (right) grew fat.

In contrast, lymphocytes in both types of endothelial cell grafts expressed higher levels of genes known to be involved in dampening the immune response and inducing self - tolerance.

The research also revealed that sunflower oil induced fibrosis, ultrastructural alterations, gene expression blockades and high oxidation.

Not only did a high percentage of embryonic cells get repaired, but also gene correction didn't induce any detectable off - target mutations and genome instability — major concerns for gene editing.

Plasmablasts induced by pandemic H1N1 infection are highly cross-reactive and have accumulated particularly high levels of variable gene somatic hypermutation.

This will be achieved by exposing the coral to seawater with high calcium concentrations to induce an alteration in gene expression profiles, identified using a DNA microarray analysis.

They previously showed that knocking out (eliminating) the gene Tff1 in mice induces gastric lesions that include low - and high - grade dysplasia and adenocarcinomas.

Finally, we show that a high proportion of these novel induced genes are taxonomically restricted, highlighting the rapid evolution of immune gene content.

Excluding genes with homology evidence for immune function, 42.24 % of induced genes encode proteins with bioinformatic evidence for a signal peptide, a significantly higher fraction that the 15.95 % of non-induced and non-immune genes that encode a protein with bioinformatic evidence for a signal peptide (P = 3.4 × 10 − 15, Fisher's Exact Test).

An anti-cancer diet also needs to be low or moderate in complete protein and high - insulemic index foods (to reduce growth promoting IGF - 1), and perhaps low in methionine specifically while high in fiber, phytochemical hormetics (to induce endogenous antioxidant responses and toxin removal), epigenetically active compunds (to reexpress tumor suppressor genes for induce cellular senescence or apoptosis), inflammation inhibitors, and antiangiogenetic compounds.

A collectivistic culture values harmony within the group, and the individual gain is considered to be less important than improvement of the social group.14 Embarrassment may be more common in collectivistic cultures because it is induced by external sanctions.15 «Taijin kyofusho» (the fear of offending or embarrassing the other person) is an example of a culturally specific expression of anxiety in Asian countries.16 Biological evidence also showed that people who live in collectivist cultures are more likely than those in individualistic cultures to have a form of the serotonin transporter gene that correlates with higher rates of anxiety and depression.17