All three compounds were able to
induce luciferase expression, demonstrating their ability to overcome Bach1 repression of HMOX E2 - dependent transcription (Figure 6C).
Not exact matches
In contrast, the ability of both CoPP and HPP - 4382 to
induce HMOX1 E2 ARE - dependent
luciferase expression in the presence of the mutant Bach1 protein was sharply inhibited.
Second, in IRF - 9 — deficient U2A cells, IFNα -
induced luciferase activity was detected only when enforcing IRF - 9
expression in these cells (Fig. 1D).