Sentences with phrase «induce protein synthesis»

Like Leucine, Isoleucine is known for its ability to induce protein synthesis.

p70S6K, a key element of mTOR pathway, promotes cell growth by inducing protein synthesis and cell survival by phosphorylating (inactivating) the proapoptotic protein BAD (31, 32).

According to a study conducted in Finland, colostrum IGF - 1 induces protein synthesis, which leads to an increase in lean muscle mass without a corresponding rise in adipose (fat) tissue.

Not exact matches

In patients with ALL, this leads to a sharp fall in serum levels of asparagine, hindering protein synthesis in malignant cells and inducing apoptosis, or programmed cell death.»

I said, «Oh, it's got to do with nuclear protein and inducing melanin synthesis in albino chickens.»

The treatment induced changes in the synthesis of 101 proteins and ELISA analysis revealed a sixfold higher secretion of type II collagen compared to control cells.

L - arginine is a choice of molecule to induce AP as it causes dose - dependent selective necrosis of acinar cells by ROS and ER stress, also by inhibiting polyamine synthesis in acinar cells resulting in inhibition of protein metabolism [31, 32].

Testing eight different combinations of the corrective tRNAs, each designed with or without the RP import signal, its modified aminoacyl stem, or the MTS, they found that with the inclusion of all three modifications — and only with their inclusion — expression of their constructs induced a substantial increase in mitochondrially - encoded protein synthesis (6 -8-fold) and respiration (~ 2.5-fold) in mutant cybrid cells.

Cyclohexamide - induced block of new protein synthesis shows that Oct4 protein has a half - life of approximately 90 minutes in these cells (Figure 1E), and treatment with 10 µM MG - 132 for an hour resulted in a significant increase in Oct4 protein levels (Figure 1F).

That's because leucine plays a crucial role in muscle protein synthesis, while isoleucine and valine induce glucose uptake into cells.

High glycemic index (GI) carbs in particular, cause an insulin spike, which not only helps restore muscle glycogen, stimulates protein synthesis and kick starts the recovery process, it also helps lower the exercise - induced rise in cortisol.

Also noted by one study was a decline in C - reactive protein (CRP) 52, potentially the most widely accepted of the inflammatory markers and whose hepatic synthesis is induced by pro-inflammatory cytokines.94

MASSACR3 increases blood flow and vascularity, induces muscle hypertrophy, stimulates protein synthesis and reduces muscle atrophy.

This pathway induces leucine - mediated protein synthesis.

From the standpoint of protein synthesis and muscle repair, IGF - 1 injections have also been shown to enhance the anticatabolic effects of insulin and to increase the protein synthesis normally induced by growth hormone.

It has been reported that BCAA supplementation before exercise attenuates the breakdown of muscle proteins during exercise in humans and that leucine strongly promotes protein synthesis in skeletal muscle in humans and rats, suggesting that a BCAA supplement may attenuate muscle damage induced by exercise and promote recovery from the damage.

Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin -, amino acid - and exercise - induced signalling

However, one possibility is that BCAA may attenuate exercise - induced protein breakdown, while leucine may stimulate muscle protein synthesis.

Intriguingly enough, it has been shown that three months of aerobic exercise decreases ET - 1 concentrations in both young and elderly subjects.6 Moreover, 45 minutes of moderate - intensity treadmill running in 13 men and women 70 years of age completely restored insulin - induced increases in protein synthesis.6 Those changes were associated with a drop in ET - 1.

Moreover, L - Leucine induces muscle growth by helping in protein synthesis.

It improved nitrogen retention which is very helpful to repair and rebuilding of new muscle tissues.They decrease exercise - induced muscle damage and promote muscle protein synthesis.

Retention of nitrogen that helps in the synthesis of protein, the building blocks of protein thereby inducing their growth.

Sarcopenia, the age - related pathological loss of skeletal muscle mass and muscle function, is largely related to an impaired sensitivity of muscle protein synthesis to postprandial anabolic stimuli induced by amino acids, insulin, and other protein metabolism - related nutrients and hormones.»

There are many that argue, since low reps stimulate all the muscle fibers and moderate reps induce sarcoplasmic protein synthesis, that there is really no need to do high rep sets.

Diazoxide - induced insulin deficiency greatly reduced muscle protein synthesis in rats: involvement of EIF4E

Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign