Sentences with phrase «induce tumor formation»

Likewise, wild - type MELK cooperates with a second oncogene, for example NeuT, to induce tumor formation in vivo.

Furthermore, although mutation of p21waf1 / cip1 is uncommon in cancers (12), p21waf1 / cip1 - deficient mice show susceptibility to spontaneously or chemically induced tumor formation (13 — 15).

Not exact matches

«It was really surprizing to realize that oncogenic Pik3ca in basal cells induced the formation of luminal tumours, while its expression in luminal cells gave rise to heterogeneous and more aggressive tumors including basal - like tumors,» comments Alexandra Van Keymeulen, the first author of the paper.

This stress, which is notably induced in pre-cancerous lesions, is characterised by an increased DNA replication rate, which provokes DNA damage and genome instability, major drivers of tumor formation.

Using a fluorescent protein to detect Rgs16 expression, the investigators found that this gene is induced by pancreatic tumor formation starting from its earliest manifestation as ductal neoplasm all the way to advanced solid tumor in a spatially and temporally coincidental manner.

Molecular studies identify new diagnostic and therapeutic concepts to prevent and treat these viral diseases or to prevent the formation of virus - induced tumors.

Inhibition of ROS induced by reflux may be a useful strategy for preventing DNA damage and decreasing the risk for tumor formation caused by GERD, they concluded.

The virus can induce formation of tumors in as little as 10 days.

Cancer - causing viruses typically contain oncogenes, genes that induce the formation of tumors.

They also act aggressively against cancer by preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.

Standard chemo with radiation actually intentionally induces formation of free radicals which has a selective effect on tumors and normal tissue.