Not exact matches
«Understanding the molecular mechanism that leads to CD8 T cell exhaustion brings us a step closer to developing strategies to
induce optimal T cell
responses that can successfully clear infections and kill tumor cells,» explains postdoctoral researcher and co-lead author Renata M. Pereira, Ph.D. «Conversely, it may allow us to interfere with
autoimmune responses that paradoxically depend on the same protein.»
It included a 1994 report from the Institute of Medicine that said it was biologically plausible for a vaccine to «
induce... an
autoimmune response... by nonspecific activation of the T cells directed against myelin proteins.»
It is critical to understand how best to design a cancer vaccine such that it recognizes only the tumor without
inducing an equally destructive
autoimmune response to normal issue.
In this study, the researchers were able to block the
autoimmune response by
inducing immune tolerance to alpha - myosin.
ß1 - Adrenergic Receptor Contains Multiple IAk and IEk Binding Epitopes That
Induce T Cell
Responses with Varying Degrees of
Autoimmune Myocarditis in A / J Mice.
These bacteria
induce an inflammatory
response in our body and cause an increase in IL - 6, a Th - 1 inflammatory marker associated with both
autoimmune conditions.
Another potential mechanism through which iodine exacerbates or
induces Hashimoto's is by up - regulating Th17 cells, the immune cell subset responsible for tissue destruction in
autoimmune disease, and by suppressing development of regulatory T cells, the population that invokes oral tolerance to arrest
autoimmune responses (31).