Sentences with phrase «induced by a drug»

«Some psychotic disorders may be induced by drugs designed to combat effects of epilepsy.»

In fact, «it also opens the way to using drugs that block the NMDA receptor — another regulator of neuronal excitability leading to hypersensitivity in painful processes — and to avoiding the serious side effects resulting from their high toxicity — sedation, nausea, dissociative reactions, behaviour modification, etc. — nowadays induced by these drugs,» argues Hipólito.

This is necessary for example to check what structural changes might be induced by a drug binding to a target.

He will be looking at mouse models of osteoporosis and determining whether reducing mTOR signaling (induced by the drug rapamycin) influences age - related bone loss.

Movement in rats (locomotor) is often induced by drugs (eg.

• What the experts say: Though the FDA did not conclude definitively that the events reported were induced by the drugs, the agency in June 2009 requested that the manufacturers of these drugs include a precaution about neuropsychiatric events in their prescribing information and labeling.

It does not have any side effect similar to those induced by drugs.

In addition to direct stomach involvement, vomiting may be a symptom of disease of the kidneys, liver, or pancreas, or could be induced by drugs, electrolyte imbalance, or stress.

Not exact matches

PCSK9 inhibitors, the main ingredients in Amgen's Repatha and Sanofi and Regeneron's Praluent treatments, were first approved by the Food and Drug Administration in July 2015 for use by patients with a family history of high cholesterol or those who suffered high - cholesterol - induced heart attacks.

The mystics often seek to experience God through altered states of consciousness, generally induced by trance or meditation instead of drugs.

People who are «converted» could be influenced not only by indoctrination and peer pressure, but also hallucinations induced by chemical imbalance, sleep deprivation, dehydration, malnourishment, alcohol, drugs, etc..

Nikki Six from Motley crew came back from the dead also after a drug induced death / coma — The jesus thing is very easily explainable by modern science and to simple minds back then it was and could only be the work of a god.

This is a kind of mysticism, reported by many as the experience of prayer or visions and by others as drug - induced.

Are you aware that ongoing investigation into Matthew Shepard's death leads to the possibility that it was not fueled by hatred but was simply a drug deal gone bad and the result of drug induced rage on the part of his murderers?

We can not violate our vows by participating in the government's program to provide access to abortion - inducing drugs.

Another study from Nigeria published in December of 2017 is titled Antioxidant and anti-inflammatory effects of virgin coconut oil supplementation abrogate acute chemotherapy oxidative nephrotoxicity induced by anticancer drug methotrexate in rats.

In animal models, long - term fluoxetine administration blocks the oxytocin release induced by serotonergic drugs.14

She also instinctively bends her legs completing the protective space around the baby, making it impossible for another person to roll onto the baby without first coming into contact with her legs.15, 16 A breastfeeding mother who co-sleeps with her baby (and has not consumed alcohol, illegal or sleep - inducing drugs or extreme fatigue) also tends to be highly responsive to her baby's needs.17, 18 Studies show more frequent arousals in both mothers and babies when they co-sleep, and some researchers have suggested that this may be protective against sudden unexpected infant deaths.19 — 21 Babies are checked by their mother and breastfeed more frequently when co-sleeping than when room - sharing.22, 23

Denosumab, a fully human monoclonal antibody drug, binds specifically to RANK - ligand (RANKL) and inhibits osteoclast - induced bone resorption by preventing the binding of RANKL to RANK.

Dartmouth researchers previously demonstrated that STK17A is a protein that is induced when DNA is damaged by the chemotherapeutic drug cisplatin.

Secretion was then stimulated by a synthetic small - molecule drug that induces protein disaggregation.

In short, by driving dopamine, nicotine appeared to ease the tremors and tics caused by Parkinson's, and even the movement disorder induced by the major Parkinson's drug.

The researchers decided to use caffeine to induce citric acid, another edible material produced by plants, to form a polymer network along with polyethylene glycol (PEG), a biocompatible polymer that has been used in drugs and consumer products such as toothpaste for many decades.

There are currently no devices approved by the U.S. Food and Drug Administration (FDA) to control general anesthesia or induced coma, but there is a device available in Europe and South America, based on an algorithm that uses the patient's EEG to compute an index on a 100 - point scale.

The drug reduced the pain hypersensitivity induced by the nerve injury (or accompanying inflammation) but did not affect nociceptive pain — the protective pain sensation that helps us avoid injury.

A new University of Iowa study in mice shows that drug - induced changes to the gut microbiome can cause obesity by reducing the resting metabolic rate — the calories burned while sleeping or resting.

The researchers showed that a two - day treatment regimen with partial or selective PPAR - γ agonists (Telmisartan and Rosiglitazone — both FDA - approved drugs) ameliorated the pathological outcomes of infection in mice by inducing expression of glucose transporters.

There's roughly a 30 to 50 percent overlap in the two mechanisms, which is very interesting because it suggests that one of the ways in which antidepressant drugs work is by inducing in depressed individuals some of the same modifications that occur naturally in those individuals who are inherently more robust or resilient.

A therapeutic screening center, headed by Lee Rubin at the Harvard Department of Stem Cell and Regenerative Biology, is dedicated to using induced pluripotent stem cells to find new drugs for genetic diseases.

Attrition of novel drug candidates due to cardiovascular liabilities (including proarrhythmic risk due to delayed ventricular repolarization and Torsades - de-Pointes arrhythmia) remains a hurdle for drug discovery efforts, a hurdle which may be mitigated by the use of human induced pluripotent stem - cell derived (hiPSC)- cardiomyocytes.

Therapists also gave patients drugs that induced vomiting or paralysis, or exposed them to noxious chemicals like ammonia, whenever they were aroused by same - sex photos.

Cellular - level changes to a part of the brain's reward system induced by chronic exposure to the psychoactive component of marijuana may contribute to the drug's pleasurable and potentially addictive qualities, suggests a study in young mice published in JNeurosci.

A research team led by Oliver Schlüter (University of Pittsburgh, PA, USA) found that cocaine - induced place preference in mice — returning to places where the drug was previously received — does not depend on lasting rewiring of neurons in the NAc.

«The data from these two Phase III trials conducted in Europe and in the U.S. support the effectiveness of this novel photo - protective drug, offering the patients in Europe — where the drug has been approved by the European Medicines Agency — the opportunity to perform their daily functions without the pain induced by sun exposure,» said Robert J. Desnick, PhD, MD, Principal Investigator of the U.S. Trials and Dean for Genetic and Genomic Medicine, Icahn School of Medicine.

In examining these remaining myeloma cells, the Yale team discovered a previously unidentified biologic pathway induced by the immune modulating drugs that enabled the residual cancer cells to survive and proliferate.

The tumor - feeding effects of behaviorally and pharmacologically induced stress, both of which were mediated by FAK, were inhibited by the adrenaline - blocking drug propranolol.

One signal, called histamine - induced itching, is caused by bug bites, for example, and responds to antihistamine drugs, such as Benadryl.

The other type of itching, called called chloroquine - induced itching, often is experienced by malaria patients who take the drug chloroquine to control their symptoms.

Opiate addiction is largely controlled by the formation of powerful reward memories that link the pleasurable effects of opiate - class drugs to environmental triggers that induce drug craving in individuals addicted to opiates.

The study raises the possibility that drugs known as JAK inhibitors could be used to restore hair growth in multiple forms of hair loss such as that induced by male pattern baldness, and additional types that occur when hair follicles are trapped in a resting state.

The finding suggests that the drug — methylnaltrexone, approved for use by the United States Food and Drug Administration in 2008 to treat opioid - induced constipation — could play a role in cancer therdrug — methylnaltrexone, approved for use by the United States Food and Drug Administration in 2008 to treat opioid - induced constipation — could play a role in cancer therDrug Administration in 2008 to treat opioid - induced constipation — could play a role in cancer therapy.

Struck by the suffering of a friend with cancer who complained more about his morphine - induced constipation than his cancer - related pain, Goldberg tested derivatives of naltrexone, an established morphine - blocking drug.

This makes our discovery promising, because even a small increase in the ATM activity induced by the SMRT drug can potentially translate to positive effects for patients, slowing disease progression and hopefully improving their quality of life.»

Dopamine prevented neutropenia (low neutrophil count) induced by 5 - FU, an anti-cancer drug commonly used to treat gastrointestinal cancers.

The drugs work by jamming some of cancer cells» machinery to induce cell death.

The SNRK - lacking mice maintained their extra weight even when treated with a drug known to induce weight loss in rodents by activating brown fat.

In a meeting sponsored by the National Cancer Policy Forum of the National Academies» Institute of Medicine in Washington, D.C., Fan and 15 other experts in the field described the benefits of using pet dogs with naturally occurring (rather than laboratory - induced) tumors in early cancer drug trials.

Development of this drug was based on earlier work by Dr. Feener's lab, which showed that activation of PKal can induce retinal edema in experimental models of diabetic retinopathy.

Recent research by Miettinen et al (2018) reveals that senescence induced by this class of drugs is mediated by proteasome hyper ‐ activation.

Unlike «closed» systems, in which cells are enclosed in chips, Griffith's open platform would allow researchers to work directly with the cultured tissue — for example, by chemically inducing inflammation and testing how different drugs interact with the inflamed tissue.