Sentences with phrase «induced by a growth»

The prevalence of fatty liver and NASH are very high in patients with growth hormone (GH) deficiency, and the research group has demonstrated that this was caused by a lack of insulin - like growth factor - I (IGF - I), which is mainly induced by growth hormone.

From the standpoint of protein synthesis and muscle repair, IGF - 1 injections have also been shown to enhance the anticatabolic effects of insulin and to increase the protein synthesis normally induced by growth hormone.

I think it is the overgrowth of the skin being induced by a growth hormone.

Not exact matches

With the global economy «floating on an ocean of credit,» the current acceleration of credit via central bank policies will likely produce a positive rate of real economic growth this year for most developed countries, PIMCO chief Bill Gross writes in his latest monthly commentary, but «the structural distortions brought about by zero bound interest rates will limit that growth and induce serious risks in future years.»

Over the past 30 years, during which earnings growth hasn't been stellar, market values have instead been driven by Federal Reserve - induced low interest rates leading to corporate share repurchase strategies and merger and acquisition activity.

The most recent GDP release is a case in point: the drag induced by the drop in inventories subtracted more than two percentage points from the annualized fourth quarter GDP growth rate.

is a case in point: the drag induced by the drop in inventories subtracted more than two percentage points from the annualized fourth quarter GDP growth rate.

In contrast, import volumes have expanded rapidly, buoyed by strength in domestic demand and price falls induced by a stronger exchange rate, though growth has begun to moderate more recently.

Economic growth in the 1990s, combined with the fiscal prudence induced in the Clinton administration by the health - care debacle of 1993 - 94, brought the spending - income ratio down, so that what seemed prudent in 1992 and now appears to be wildly spendthrift is in fact well within the nation's means.

Goji's are reported to have anti-aging properties and show anti-tumor activities against various types of skin cancer cells by inhibiting tumor growth and inducing apoptosis.

Note that means that the policy of adding lanes was able to negate the effects of traffic growth by both induced traffic and population growth over this period of 10 years.

By promoting DNA demethylation, high - dose vitamin C treatment induced stem cells to mature, and also suppressed the growth of leukemia cancer stem cells from human patients implanted in mice.

Among dozens of mouse studies, he presented work led by Moderna Co-Founder Kenneth Chien, then at Harvard Medical School in Boston, showing that mice recovering from induced heart attacks survived longer and had stronger hearts when injected with mRNA encoding a protein that drives blood vessel formation — vascular endothelial growth factor (VEGF).

In addition, using methods for the analysis of regulatory networks developed by the Califano lab in the Center for Computational Biology and Bioinformatics, Department of Systems Biology, the researchers identified a number of transcription factors (gene regulators) that have the potential to mimic the environmental signals that trigger papillae to induce new hair growth.

The paper is titled, «Microenvironmental reprogramming by three - dimensional culture enables dermal papilla cells to induce de novo human hair follicle growth.»

Their research, published in the Journal of Clinical Investigation, compared the differences between hypertrophic heart growth in rats as a result of exercise — which is beneficial — and heart growth induced by pathology — in this case, increased load.

The long - term facilitation of synaptic efficacy that is induced by serotonin in dissociated cell cultures of sensory and motor neurons of Aplysia is accompanied by the growth of new synaptic connections.

In the model, the severity of hypoxia is driven by a combination of physical factors such as the thickness of the dense, bottom layer of water during stratification, the degree of wind - driven vertical mixing, and the growth of phytoplankton induced by phosphorus loading.

They can induce plant malformations such as galls and disturb the normal growth of plants by piercing their cells with saliva.

The study raises the possibility that drugs known as JAK inhibitors could be used to restore hair growth in multiple forms of hair loss such as that induced by male pattern baldness, and additional types that occur when hair follicles are trapped in a resting state.

«Alcohol also damages the liver by allowing bacteria to infiltrate: Natural gut antibiotics diminished by alcohol leave mice more prone to bacterial growth in the liver, exacerbating alcohol - induced liver disease.»

Fouke says his findings could improve models used by oil and gas geologists that predict underground spaces for drilling, because microbe - induced mineral growth may close off these spaces.

Western Wildfires — The increasingly destructive and widespread fire seasons of recent years are likely to continue due to a combination of increased drought and land development encroaching on naturally burning landscapes, along with a climate change — induced fuel boom (enhanced plant growth and a shift to more woody species) exacerbated by fire - suppression efforts leading to more abundant plant matter to fuel violent blazes, according to ecologist Dominique Bachelet of Oregon State University in Corvallis and The Nature Conservancy.

These results suggest that the additional muscle mass induced by follistatin in Mstn null mice results from inhibition of additional ligands that act predominantly to regulate muscle fiber growth.

Changes in cell junctions induced by inhibition of epidermal growth factor receptor in oral squamous cell carcinoma cells.

Growth inhibition induced by antiprogestins RU - 38486, ORG - 31710, and CDB - 2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2.

They noticed that upon initial charging, the tin oxide is subject to lithiation - induced solid - state armorphization, followed by nucleation and growth of lithium tin alloy particles dispersed in the lithium oxide matrix.

On the one hand, it regulates progression from premalignancy to malignancy, most likely by preventing oxidative stress - induced death of HCC - initiating cells, thereby allowing such cells to accumulate multiple oncogenic mutations, while promoting their growth through mTORC1.

Nakano S, Nagasawa T, Ijiro T, Inada Y, Tamura T, Maruyama K, Kuroda J, Yamazaki Y, Kusama H, Shibata N. Bezafibrate prevents hepatic stellate cell activation and fibrogenesis in a murine steatohepatitis model, and suppresses fibrogenic response induced by transforming growth factor - beta1 in a cultured stellate cell line.

Competitive enhancement of HGF - induced epithelial scattering by accessory growth factors.

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

Root growth improvement of mesquite seedlings and bacterial rhizosphere and soil community changes are induced by inoculation with plant growth - promoting bacteria and promote restoration of eroded desert soil — Cristina Galaviz — Land Degradation and Development

Research Paper G9a stimulates CRC growth by inducing p53 Lys373 dimethylation - dependent activation of Plk1 Jie Zhang, Yafang Wang, Yanyan Shen, Pengxing He, Jian Ding, Yi Chen Theranostics 2018; 8 (10): 2884 - 2895.

p70S6K, a key element of mTOR pathway, promotes cell growth by inducing protein synthesis and cell survival by phosphorylating (inactivating) the proapoptotic protein BAD (31, 32).

Oncostatin M Induces Growth Arrest by Inhibition of Skp2, Cks1, and Cyclin A Expression and Induced p21 Expression

The latest study builds on earlier research from Izpisúa Belmonte's laboratory showing that extra limbs could be induced to grow in embryonic chicks by implanting beads soaked in fibroblast growth factor (FGF).

Simultaneous knockdown of GBP1 and GBP2 showed more severe growth retardation, and this reduction in growth rate was indistinguishable from that induced by overexpressing TSC1 and TSC2 in the fat body.

By binding to the insulin receptor, ILPs induce a phosphorylation cascade that ultimately induces growth in the target tissues [1,5,7].

In - vivo treatments of xenografted tumors showed significant tumor growth inhibition induced either by rituximab or gemcitabine alone and an impressive efficacy of combined treatment.

Given that Smad 1/5 are required for neurite growth induced by BMP ligands (Figure 2), we next sought to test the hypothesis that the miR - 181a inhibitor mediated Smad1 / 5 activation is responsible for the increase in neurite growth following miR - 181a inhibition.

Having confirmed that the miR - 181a target genes were expressed in these cultures, we next examined the functional importance of the BMP / GDF receptor - regulated Smads, Smad1 and Smad5, for the neurite growth induced by BMP / GDF ligands.

These signals not only regulate systemic growth and metabolism but also neuroblast reactivation by inducing ILP production in the glial cells [26,38,39].

We used a bioninformatics analysis to identify that miR - 181a targets components of the bone morphogenetic protein (BMP) signalling pathway, including the transcription factors Smad1 and Smad5, which we find are expressed by rat mDA neurons and are required for BMP - induced neurite growth.

Similarly, Smad5 siRNA partially prevented the neurite growth induced by miR - 181a inhibition.

Novel methods and pharmaceutical compositions suitable for modulating bone growth and remodeling, preventing bone diseases, inducing bone growth or repair by cannabinoid receptor - mediated effects on bone cells is disclosed.

We report that CTPB promoted the survival and neurite growth of the SH - SY5Y cells, and also protected these cells from cell death induced by the neurotoxin 6 - hydroxydopamine.

We found that canonical signaling by the EphB4 receptor is low in breast cancer cells and that ephrin - induced stimulation of EphB4 kinase activity inhibits breast cancer cell malignancy in culture and tumor growth in vivo (Figure 1A) through inhibition of the CRK proto - oncogene.

Further studies showed that Notch1 knockdown in NSCLC helps induce cell death (which inhibits tumor initiation and growth); this process is mediated by p53, and thus the effects of inhibiting Notch1 require functional p53.

Finally, we demonstrate that daily oral administration of melatonin can increase bone accrual during growth and can cure ovariectomy - induced structural and functional degeneration of bone by specifically increasing bone formation.

This study describes for the first time that suboptimal IVC affects male fertility and that a paternal IVC effect induces intergenerational transmission of a glucose metabolism alteration and hepatomegaly phenotype to their male offspring, confirming that programming events triggered by preimplantational growth restrictions may induce persistent and transmissible phenotypic abnormalities in subsequent generations.