Sentences with phrase «induced by components»

Five Xanthomonas type III effectors suppress cell death induced by components of immunity - associated MAP kinase cascades

Not exact matches

A research group led by Olga Malyshevskaya and Yoshihiro Urade of International Institute for Integrative Sleep Medicine (WPI - IIIS), University of Tsukuba, discovered that seizures, a life - threatening condition, can be induced by natural Δ9 - tetrahydrocannabinol (Δ9 - THC, main constituent of marijuana) or the synthetic cannabinoid JWH - 018 (main component of synthetic blend «Spice») in mice.

Cellular - level changes to a part of the brain's reward system induced by chronic exposure to the psychoactive component of marijuana may contribute to the drug's pleasurable and potentially addictive qualities, suggests a study in young mice published in JNeurosci.

To their surprise, the researchers found that T cells were the most important component of the anti-tumor response induced by the antibody - IL - 2 combination.

According to researcher Kwang Soon Kim, «In early life, the intestinal environment is more skewed to generate a tolerogenic response, presumably helped by certain tolerance - inducing components in the milk, and from the rapid generation of pTreg cells upon introduction of solid food.»

iTeos uses a platform of in vitro and ex vivo screening assays to reproduce immunosuppression induced by different components of the tumor microenvironment.

It is well known that HDAC inhibitors are potent anticancer drugs in hematopoietic malignancies, including lymphoma.19 — 21 The aim of using HDAC inhibitors is to restore normal histone modification patterns through inhibition of various components of the epigenetic machinery.22, 23 In B - cell lymphoma, HDAC inhibitors can rescue deficits in histone acetylation induced by EP300 / CREBBP mutations, 24 rendering tumor cells more sensitive to suberoylanilide hydroxamic acid.25 This can explain why chidamide also has favorable efficacy on PTCL - NOS patients bearing EP300 / CREBBP mutations.

We used a bioninformatics analysis to identify that miR - 181a targets components of the bone morphogenetic protein (BMP) signalling pathway, including the transcription factors Smad1 and Smad5, which we find are expressed by rat mDA neurons and are required for BMP - induced neurite growth.

The idea that both STAT2 and IRF - 9 were basic components necessary for RIG - G expression was also supported by the fact that ATRA could not only induce the total amounts of STAT2 and IRF - 9 proteins but also increase the tyrosine phosphorylation level of STAT2 in NB4 cells (Fig. 1A).

«Our method not only uses soluble factors that guide kidney development in the embryo but, by growing and differentiating stem cells on extracellular matrix components that are also contained in the membrane separating the glomerular blood and urinary systems, we more closely mimic the natural environment in which podocytes are induced and mature,» said Musah.

In 2010, we formally demonstrated ADE by developing a mouse mode of ADE - mediated disease, and we began to dissect the contribution of humoral vs. cellular immune components in dengue vaccine - mediated protection using model vaccine candidates as tools to probe the mechanisms by which the vaccine - induced immune responses in mice contribute to protection vs. ADE.

Some of their goals include the unravelling of disease mechanisms by using nanomaterials to track cellular components and probe the chemical niche of the cells, the transformation of adult human cells into induced pluripotent stem cells and the delivery of drugs directly to immune and cancer cells.

Within this broad topic we are particularly interested in characterising (i) the molecular mechanism by which these photoreceptors mediate light - dependent entrainment of the circadian clock, (ii) the components mediating, in a light - quality - dependent fashion, nucleocytoplasmic partitioning of phytochromes and UVR8, (iii) how phosphorylation and sumoylation of these photorecepors and other signalling components modulate red / far - red and UVB - induced signalling, and (iv) to what extent intercellular and cell - autonomous events contribute to phytochrome and UVR8 regulated photomorphogenesis.

Manganese is also a component of an essential enzyme called superoxide dismutase, which is found in the cells» mitochondria and plays the vital role of protecting the cells from damage induced by free radicals.

By denying viewers the ability to rest their eyes on any one component for too long, her works are both mesmerizing and disconcerting, inducing frustration as one tries to pinpoint figures or structures within the compositions.

Human induced trend has two components, namely (a) greenhouse effect [this includes global and local / regional component] and (b) non-greenhouse effect [local / regional component]-- according to IPCC (a) is more than half of global average temperature anomaly wherein it also includes component of volcanic activities, etc that comes under greenhouse effect; and (b) contribution is less than half — ecological changes component but this is biased positive side by urban - heat - island effect component as the met network are concentrated in urban areas and rural - cold - island effect is biased negative side as the met stations are sparsely distributed though rural area is more than double to urban area.

The biosphere consists of animals and vegetation and normally changes relatively slowly; reduced rainfall might take years to alter vegetation cover significantly, although certain components (such as humankind) are capable of inducing quite rapid local changes (by setting oil - fields ablaze, for example).

Given the increased levels of certainty regarding human - induced global warming (from 90 to 95 %), more robust projections on sea - level rise and data on melting of ice sheets, and the «carbon budget» for staying below the 2 °C target, the WGI conclusions together with other AR5 component reports are likely to put more pressure on the UNFCCC parties to deliver by 2015 an ambitious agreement that is capable of preventing dangerous anthropogenic interference with the climate system.

Graph four in http://www.vukcevic.talktalk.net/TMC.htm shows that change in the Antarctic magnetic field on century scale are of order of 1 - 2 % which is commensurate with changes in Z component frequently induced by geomagnetic storms.

It goes on to say that the major components have no dipole moment so that their vibration and rotational energy states can not be excited directly by absorption of radiation, but dipole moments are induced during the collision process.

If the TLT algorithm is impacted by either seasonal or latitudinal influences, would that induce another source of bias in the measurements, such as increasing the stratospheric component at polar latitudes?

«We show that the expertise and prominence, two integral components of overall expert credibility, of climate researchers convinced by the evidence» of human - induced climate change «vastly overshadows that of the climate change skeptics and contrarians,» Mr. Anderegg and the other authors write in their paper.

Forcing by non-CO2 emissions includes a component driven by the response of the carbon - cycle to temperature changes induced by those emissions (as in the calculations for CO2 itself) based on a reduced carbon uptake of 1 GtC per degree warming (Arora et al. 2013; Collins et al. 2013b).

Although one of the ES components mentioned above, the global economy, is about to inadvertently transform that face through massive emissions of greenhouse gases (GHGs) and the so - induced planetary warming, one other crucial component, the human brain, struggles to advertently preserve it by constructing clumsy institutions like the United Nations Framework Convention on Climate Change (http://unfccc.int/resource/docs/convkp/conveng.pdf).

The patents cover an active stylus LCD device that mitigates noise induced by one or more electrical components of the display, and a method for mitigating LCD circuitry noise in an active stylus touch device.