Diabetes
induced by insulin - resistance states are less common «other specific types» of canine diabetes.
Not exact matches
Fibre and fat curb the
insulin spike
induced by high - glycemic / sugar foods.
Atkins rejects the advice of the food pyramid, instead asserting that the tremendous increase in refined carbohydrates is responsible for the rise in metabolic disorders of the 20th century, and that the focus on the detrimental effects of dietary fat has actually contributed to the obesity problem
by increasing the proportion of
insulin -
inducing foods in the diet.
A study in this issue of JCI Insight demonstrates that mice lacking the proinflammatory signaling molecule TAK1 are protected from obesity and
insulin resistance
induced by a high fat diet.
«The chemicals produced
by cooking meats at high temperatures
induce oxidative stress, inflammation and
insulin resistance in animal studies, and these pathways may also lead to an elevated risk of developing high blood pressure,» said Gang Liu, Ph.D., lead author of the study and a postdoctoral research fellow in the department of nutrition at the Harvard T.H. Chan School of Public Health in Boston.
The
insulin -
induced stimulation of ACTH release was blocked in both the control and lesioned animals
by prior treatment with either the beta - adrenergic antagonist propranolol or the glucocorticoid analog dexamethasone.
Also released
by the intestine during the absorption of meal, this hormone stimulates the secretion of
insulin, inhibits the secretion of glucagon and
induces the feeling of satiety.
In contrast, in mice with normal immune systems, emulsifiers
induced low - grade or mild intestinal inflammation and metabolic syndrome, characterized
by increased levels of food consumption, obesity, hyperglycemia and
insulin resistance.
Early on she received electroshock therapy and
insulin shock therapy, in which doctors
induced a coma
by lowering her blood sugar level.
Atkins rejects the advice of the food pyramid, instead asserting that the tremendous increase in refined carbohydrates is responsible for the rise in metabolic disorders of the 20th century, and that the focus on the detrimental effects of dietary fat has actually contributed to the obesity problem
by increasing the proportion of
insulin -
inducing foods in the diet.
Sucrose is made up of glucose and fructose and it has been shown that diets very high in sucrose or fructose (~ 60 - 70 %
by energy) can
induce hypertriglyceridemia,
insulin resistance and fatty liver.
Binge drinking
induces whole - body
insulin resistance
by impairing hypothalamic
insulin action
SOCS3,
by doing this,
by inducing degradation of a number of the receptor itself and potentially STAT3 and JAK2, can block this signal, so this, of course, can
induce insulin resistance.
I should mention that the leptin signal is not the only signal that's involved in regulating food intake, there are a number of other signals as shown in this slide, such as TYY and CCK,
insulin itself, ghrelin, which is another hormone that's been described generally that's secreted
by the stomach, and important in
inducing hunger.
By binding to the
insulin receptor, ILPs
induce a phosphorylation cascade that ultimately
induces growth in the target tissues [1,5,7].
The prevalence of fatty liver and NASH are very high in patients with growth hormone (GH) deficiency, and the research group has demonstrated that this was caused
by a lack of
insulin - like growth factor - I (IGF - I), which is mainly
induced by growth hormone.
Sugar -
induced cephalic - phase
insulin release is mediated
by a T1r2 + T1r3 - independent taste transduction pathway in mice.
By comparing key biochemical reactions in the cells of fasted and fed scid and B6 mice, the research team was able to identify and describe the highlighted steps (formerly missing links) in the following feeding -
induced insulin signaling pathway.
Hafizur RM, Kabir N, and Chishti S. Asparagus officinalis extract controls blood glucose
by improving
insulin secretion and β - cell function in streptozotocin -
induced type 2 diabetic rats.
Research has shown that
insulin resistance, pre-diabetes, and type 2 diabetes are likely
induced by a diet high in sugar.
Low - salt diets may even cause hypertension
by inducing vascular
insulin resistance, which is a fancy way of saying a reduced vasodilatory response when
insulin acts upon our arteries and blood vessels.
In the research setting, scientists
induce insulin resistance and diabetes
by feeding laboratory animals a low carbohydrate diet high in fat and protein.
From the standpoint of protein synthesis and muscle repair, IGF - 1 injections have also been shown to enhance the anticatabolic effects of
insulin and to increase the protein synthesis normally
induced by growth hormone.
Ketogenic diets have a long history of efficacy for disorders of the CNS, most notably epilepsy.46, 47 KBs are more efficient than glucose and
induce less oxidative damage.47 Additionally, KBs are brought into the brain
by monocarboxylate transporters — independently of glucose and
insulin — so their uptake is not hindered when
insulin signaling fails.51
Additionally, deregulation of immune function,
insulin resistance, cardiovascular, and gastrointestinal disorders, as well as other pathological processes
induced by chronic stress may also profoundly affect brain homeostasis.»
Low - dose supplemental testosterone treatment in men with chronic stable angina increased exercise time preceding
induced myocardial ischemia as defined
by ST depression on EKG.80 Testosterone replacement therapy has also been proven to reduce
insulin resistance, visceral adiposity, and cardiovascular risk.
The idea is that
by eating this way post workout backloading you can take advantage exercise -
induced insulin sensitivity in your body.
Cyanidin 3 - glucoside protects 3T3 - L1 adipocytes against H2O2 - or TNF - alpha -
induced insulin resistance
by inhibiting c - Jun NH2 - terminal kinase activation.
, Anti-obesity action of gingerol: effect on lipid profile,
insulin, leptin, amylase and lipase in male obese rats
induced by a high - fat diet, 2014
Taken together, these results indicated that Cy -3-G exerts a protective role against H (2) O (2)- or TNF - alpha -
induced insulin resistance in 3T3 - L1 adipocytes
by inhibiting the JNK signal pathway.
Regulation of protein synthesis associated with skeletal muscle hypertrophy
by insulin -, amino acid - and exercise -
induced signalling
I have an even bigger problem with your assertion that the low -
insulin state
induced by the keto diet would increase K and Na requirements.
This type of diet ignores and makes no attempt to fix the underlying cause of the disease (lipid
induced insulin resistance), but rather «works»
by simply managing a symptom (excess carbohydrate in the blood).
In rodent models of T1D
induced by streptozotocin, it was found that THC mitigated the severity of the immune response, transiently prevented hyperglycemia and loss of pancreatic
insulin, and decreased expression of pro-inflammatory elements including CD3 + T cells, IL - 12, IFN - γ and TNF - α (50).
Adiponectin, among other effects, increases
insulin sensitivity — thus it would tend to promote thermogenesis not only
by its own action, but also indirectly
by enhancing
insulin amplification of leptin -
induced thermogenesis.
Diabetes Care: «Monounsaturated fat - rich diet prevents central body fat distribution and decreases postprandial adiponectin expression
induced by a carbohydrate - rich diet in
insulin - resistant subjects.»
It was only recently discovered that exercise -
induced increases in
insulin sensitivity are driven
by increased ROS production (5), and totally suppressed
by antioxidant supplements.
Improvements in body composition, glucose tolerance, and
insulin action
induced by increasing energy expenditure or decreasing energy intake.
Aro A, Uusitupa M, Voutilainen E, Hersio K, Korhonen T, Siitonen O. Improved diabetic control and hypocholesterolaemic effect
induced by long - term dietary supplementation with guar gum in type 2 (
insulin - independent) diabetes.
Engagement of the
Insulin - sensitive Pathway in the Stimulation of Glucose Transport
by Alpha - lipoic Acid in 3T3 - L1 Adipocytes Diabetologia 2000 (Mar); 43 (3): 294 — 303 These results indicate that R (+) alpha - lipoic acid directly activates lipid, tyrosine and serine / threonine kinases in target cells, which could lead to the stimulation of glucose uptake
induced by this natural cofactor.
Sarcopenia, the age - related pathological loss of skeletal muscle mass and muscle function, is largely related to an impaired sensitivity of muscle protein synthesis to postprandial anabolic stimuli
induced by amino acids,
insulin, and other protein metabolism - related nutrients and hormones.»
That can give you acne
by causing inflammation and
inducing insulin resistance, so it's important to pick a fruit where the sugar is low enough not to overpower the benefits.
Furthermore, high blood levels of
insulin can act by increasing androgenous hormonal stimulation of the ovarian theca cells as well as potentiating gonadotropin - stimulated ovarian androgen steroidogenesis — although recent data has suggested that the insulin - induced increase in ovarian hormone secretion is not accompanied by increased steroid metabolism.74 Hyperinsulinaemia may also affect the central actions of androgen by impairing progesterone inhibition of the gonadotropin - releasing hormone pulse generator.75 Insulin has also been shown to increase expression of adrenal steroidogenic enzyme mRNA47 as well as adrenal responsiveness to adrenocorticotropic hor
insulin can act
by increasing androgenous hormonal stimulation of the ovarian theca cells as well as potentiating gonadotropin - stimulated ovarian androgen steroidogenesis — although recent data has suggested that the
insulin - induced increase in ovarian hormone secretion is not accompanied by increased steroid metabolism.74 Hyperinsulinaemia may also affect the central actions of androgen by impairing progesterone inhibition of the gonadotropin - releasing hormone pulse generator.75 Insulin has also been shown to increase expression of adrenal steroidogenic enzyme mRNA47 as well as adrenal responsiveness to adrenocorticotropic hor
insulin -
induced increase in ovarian hormone secretion is not accompanied
by increased steroid metabolism.74 Hyperinsulinaemia may also affect the central actions of androgen
by impairing progesterone inhibition of the gonadotropin - releasing hormone pulse generator.75
Insulin has also been shown to increase expression of adrenal steroidogenic enzyme mRNA47 as well as adrenal responsiveness to adrenocorticotropic hor
Insulin has also been shown to increase expression of adrenal steroidogenic enzyme mRNA47 as well as adrenal responsiveness to adrenocorticotropic hormone.76
Fructose -
induced insulin resistant states are commonly characterized
by a profound metabolic dyslipidemia, which appears to result from hepatic and intestinal overproduction of atherogenic lipoprotein particles.
Apparently, exogenous carbohydrates and / or
insulin induced by exogenous carbohydrates are required for a proper utilization of dietary proteins.
Specifically, chronic hyperglycemia and hyperinsulinemia
induced by high glycemic load carbohydrates may elicit a number of hormonal and physiologic changes that promote
insulin resistance (71,77,78).
Growth hormone production
induced by progestines, leads to a rise in the blood levels of
insulin like growth factor that might lead to malignant tumors.