PRDM4 mediates YAP ‐
induced cell invasion by activating leukocyte ‐ specific integrin β2 expression
Not exact matches
Retinal
cell death can be
induced by phagocytic immune
cells that infiltrate the tissue in response to injury or infection, but the molecular signals that trigger phagocyte
invasion are largely unknown.
Bradykinin enhances
invasion of malignant glioma into the brain parenchyma by
inducing cells to undergo amoeboid migration.
Distinct c - Met activation mechanisms
induce cell rounding or
invasion through pathways involving integrins, RhoA and HIP1.
YAP interacts with PRDM4, thereby promoting transendothelial
invasion of cancer
cells by
inducing expression of the leukocyte ‐ specific integrin ITGB2.
Data obtained on the effects of kahweol on endothelial
cell invasion (as determined by a continuous fluorescent assay) clearly show that kahweol
induces an anti-invasive effect in HUVEC in a dose - dependent manner (Figure 7).
Their capacity to contract the matrix and
induce invasion of cancer
cells has been well documented.
In co-culture experiments on coated transfilters, both NAFs and CAFs
induced migration and
invasion of HT29, which are intrinsically noninvasive colon cancer
cells.
Tumor hypoxia is often linked to decreased survival in patients with breast cancer and has been shown to
induce specific molecular changes in
cells including changes that confer a more malignant phenotype such as increased proliferation (3), survival (4),
invasion (5), and metastasis (6).