Not exact matches
A short - term inhibition of Rho - kinase failed to
induce extracellular matrix production in fibroblasts or in HCS - 2 / 8 cells, while its long - term exposure increased the expressions of
chondrocyte - specific genes and differentiation markers, and also promoted the synthesis of sulfated glycosaminoglycans by chondrocytic cells.
Downregulation of microRNA - 448 inhibits IL - 1ß -
induced cartilage degradation in human
chondrocytes via upregulation of matrilin - 3.
In an attempt to bring patient - specific
induced pluripotent stem cell (iPSCs) technology closer to the clinic, researchers have created iPSCs from patient - derived
chondrocytes, using an non-integrative reprogramming method, and used these to then create large numbers of cartilage producing cells.
p38 kinase regulates nitric oxide -
induced apoptosis of articular
chondrocytes by accumulating p53 via NFkappa B - dependent transcription and stabilization by serine 15 phosphorylation.
Chlorogenic acid suppresses interleukin - 1β -
induced inflammatory mediators in human
chondrocytes.