Sentences with phrase «induced cytidine»
Global demethylation requires activation - induced cytidine deaminase (AID)- mediated downregulation of UHRF1 protein, and abolishing demethylation leaves thousands of hypermethylated regions in the iPSC genome.
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Dr. Honjo is well known for his discovery of activation - induced cytidine deaminase that is essential for class switch recombination and somatic hypermutation.
(2017) Phosphorylation promotes activation - induced cytidine deaminase activity at the Myc oncogene.
Predominant role for activation - induced cytidine deaminase in generating IgG anti-nucleosomal antibodies of murine SLE.
The activation induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes, but only during transcription.
As these cells rapidly proliferate, they also express high levels of an enzyme known as activation - induced cytidine deaminase (AID), which induces mutations in their DNA.