Notably, both intradermal injection and epicutaneous application of lauric acid effectively decreased the number of P. acnes colonized with mouse
ears, thereby relieving P. acnes -
induced ear swelling and granulomatous
inflammation.
The study found topical administration of Vinpocetine suppressed
inflammation and the overproduction of mucus
induced by Streptococcus pneumonia bacteria, improved hearing loss in the middle
ear and significantly improved bacterial clearance in animal studies.