Sentences with phrase «induced epithelial»

Competitive enhancement of HGF - induced epithelial scattering by accessory growth factors.

RNAi - mediated silencing of RASSF1A induced epithelial - to - mesenchymal transition (EMT), fomenting a motile and invasive cellular phenotype in vitro and increased metastatic prowess in vivo.

In addition, treatment with Korean red ginseng extract suppressed the expression of RSV - induced inflammatory genes and the formation of chemically reactive molecules containing oxygen, which play a role in virus - induced epithelial damage in RSV.

Their new insights are described in a paper titled «Multiple mechanisms drive calcium signal dynamics around laser induced epithelial wounds» published Oct. 3 by the Biophysical Journal.

1) Notch - 1 induces epithelial — mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells:

Notch - 1 induces Epithelial - mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

Titles: 1) Notch - 1 induces Epithelial - mesenchymal transition consistent with cancer stem cell phenotype in pancreatic cancer cells

Not exact matches

«Using Streptozotocin - induced type I diabetes and cornea epithelial wounding experimental models, we made novel observations that may soon lead to innovative therapies to treat DPN and ulcerations of the cornea and skin in diabetic patients,» said Yu.

In cell culture, high expression levels of GPR161 induced proliferation of mammary epithelial cells, disrupted the acinar structures formed by these cells, and enhanced their invasive capacity.

We show here that acidic mammalian chitinase (AMCase) is induced via a T helper - 2 (Th2)-- specific, interleukin - 13 (IL - 13)-- mediated pathway in epithelial cells and macrophages in an aeroallergen asthma model and expressed in exaggerated quantities in human asthma.

Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition (EMT).

The scientists have been able to show that the corneal epithelial cells can be cultivated and transplanted onto the eyes of rabbits with experimentally induced blindness to surgically repair the front of the eye.

But in an interesting twist, a beneficial bacterium, Lactobacillus plantarum, helps mitigate the virus - induced inflammatory response and protects gut epithelial barrier.

«It is striking that these changes, found in many human cancers, can be induced in normal mammary epithelial cells simply by varying the stiffness or composition of the matrix surrounding them.»

This study demonstrated that emulsifier - induced alterations in the microbiome were necessary and sufficient to drive alterations in intestinal epithelial cells» homeostasis, which is thought to govern tumor development.

During pregnancy, the elevated blood estrogen level induces the proliferation of mammary epithelial cells, leading to the development of the mammary gland in preparation for lactation.

Interestingly, CD44 + / CD24 − population can be generated by induction of epithelial — mesenchymal transition (EMT) by treating breast epithelial cells with EMT - inducing agents such as TGF - β1 (6).

This shows hair shafts (arrows) formed by induced pluripotent stem cell - derived epithelial stem cells.

High - salt diet induces gastric epithelial hyperplasia and parietal cell loss, and enhances Helicobacter pylori colonization in C57BL / 6 mice.

The results indicated that CD8 − T cells induced significant, albeit weak, apoptosis of allogeneic corneal epithelial cells (Figure 5A).

miR - 34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3.

«We were surprised to see that expression of the gene TSLP — which encodes a cytokine long known to be involved in epithelial - induced inflammation — was exclusive to a particular subset of tuft cells,» Haber noted.

N - acetylcysteine amide, a thiol antioxidant, prevents bleomycin - induced toxicity in human alveolar basal epithelial cells (A549).

HYPERTONIC SALINE ATTENUATES TNF -[alpha]- INDUCED NF -[kappa] B ACTIVATION IN PULMONARY EPITHELIAL CELLS.

Arsenite - induced pseudo-hypoxia results in loss of anchorage - dependent growth in BEAS - 2B pulmonary epithelial cells.

PI3K - Rac1 - JNK signaling mediates collagen I - induced cell scattering and up - regulation of n - cadherin expression in mouse mammary epithelial cells.

Cellular mechanisms of mainstream cigarette smoke - induced lung epithelial tight junction permeability changes in vitro.

L - Threonine induces heat shock protein expression and decreases apoptosis in heat - stressed intestinal epithelial cells.

Hyperoxia - induced DNA damage causes decreased DNA methylation in human lung epithelial - like A549 cells.

Research Paper Long non-coding RNAs AC026904.1 and UCA1: a «one - two punch» for TGF - β - induced SNAI2 activation and epithelial - mesenchymal transition in breast cancer Guo - Yin Li, Wei Wang, Jian - Yong Sun, Bo Xin, Xiang Zhang, Ting Wang, Qian - Feng Zhang, Li - Bo Yao, Hua Han, Dai - Ming Fan, An - Gang Yang, Lin - Tao Jia, Lei Wang Theranostics 2018; 8 (10): 2846 - 2861.

The higher scores (> 3) in some groups related primarily to the fact that virus infection had induced inflammatory infiltrates and epithelial cell necrosis with desquamation of the epithelium and collection of cellular debris in airways of these animals.

The TNF family molecules LIGHT and lymphotoxin ab induce a distinct steroid - resistant inflammatory phenotype in human lung epithelial cells.

These tumor promoting activities include inducing invasiveness and metastasis, epithelial - to - mesenchymal transition, stem cell - like features and drug resistance.

These results demonstrate that epithelial confinement alone can induce morphogenesis - like processes including spontaneous collective pulsations and transition from 2D to 3D.

TGFβ inhibits tumor initiation and progression by inducing cell cycle arrest and apoptosis; however epithelial tumorigenesis may escape this common antitumor mechanism by inducing aberrations in TGFβ signaling resulting in enhanced development and progression of human carcinomas.

«Effect of whey protein isolate on intracellular glutathione and oxidant - induced cell death in human prostate epithelial cells.»

(14) Stress increases intestinal permeability, allowing bacteria and bacterial antigens to cross the epithelial barrier into the bloodstream, inducing an immune response that alters the microbiome.

Sulforaphane induces cell cycle arrest by protecting RB - E2F - 1 complex in epithelial ovarian cancer cells.

These studies clearly provided evidence that GABA had a considerable gastroprotective effect on ethanol - induced gastric mucosal injury and gastric epithelial cells injury.

American Journal of Physiology, Lung Cellular and Molecular Physiology, 294 (3): L478ï ¿ 1/2 88, «Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke - mediated oxidative stress in human lung epithelial cells».