However, while the genetic factors responsible for reprogramming are well known, the mechanisms underlying the responses to
induced gene expression changes are not as clear.
Not exact matches
The authors describe dengue as
inducing more robust
changes in
gene expression than either strain of Zika.
According to the researchers, this is the first study to link the extreme and rapid eating -
induced changes of the Burmese python's intestines directly to
changes in
gene expression, and also the first to show how quickly
gene expression changed.
As sensitive as alternative splicing reacts to (slightly) elevated temperature, a temperature -
induced change in
gene expression by fever appears to be a logical consequence.
Further studies discovered that the BRAF protein could turn on many itch
genes, and they showed similar
changes of
gene expression in mice with chronic itch
induced by dry skin and in mice with allergic contact dermatitis, two of the skin conditions that frequently cause people to scratch incessantly.
The researchers discovered that the Activin pathway controls the ability of cocaine to
induce this
change in the neurons and determined that the Activin receptor may control this response to cocaine by regulating the
expression of a number of
genes.
By comparing
gene expression changes induced upon
expression of wild - type and mutant alleles, we inferred the activity of specific alleles.
Adaptive
changes in adipocyte
gene expression differ in AKR / J and SWR / J mice during diet
induced obesity.
Adaptive
changes in adipocyte
gene expression differ in AKR / J and SWR / J mice during diet -
induced obesity.
Our data suggest that
changes in the
expression of
genes associated with drug resistance and cancer cell «stemness»,
induced by treatment with MIA - 602, lead to a significant reduction in the efflux capacity of drug resistant cells.
This is the first study demonstrating smoking -
induced expression changes for this particular set of
genes and importantly, it is the first time partial reversibility (MUC5AC) and irreversibility (GSK3B) and has been demonstrated using two different cohorts of samples with two independent assays for
expression quantification.
Early - life stressors are known to
induce changes in
gene expression that set the stage for disease in later life.30 Thus, unfortunately, exposure to mercury in either parent, even prior to conception, can affect the child's own genetic
expression.