Sentences with phrase «induced lung tumors»

First, they induced lung tumors in the mice by giving the mice chemicals.

Not exact matches

Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem cells in the primary tumor, blocked metastasis of cancer cells from the primary tumor to the lungs, decreased the duration of chemotherapy required to induce remission and increased the duration of time after chemotherapy was stopped that the mice remained tumor - free.

The researchers expanded the relevance of these findings to lung carcinoma, showing that soluble antibodies are generally important in the tumor microenvironment to induce accumulation of MDSCs and promote cancer progression.

In addition, previous studies done in Wang's lab suggest that BCX, through a different molecular mechanism, can slow the nicotine - promoted growth of lung tumors and decrease cigarette smoke - induced lung inflammation in animal models.

It can be proposed that p21 contributes to mediate p53 - dependent tumor suppression in some tumor types, which would include histiocytic sarcomas, hemangiomas, B - cell lymphomas, and lung carcinomas, but not in other tumor types, particularly spontaneous or radiation - induced T - cell lymphomas.

Viral vectors have the main adverse effect of inducing neutralizing antibodies, while several non-viral vectors present toxic effects (e.g. respiratory system).14, 15 In an effort to deliver efficiently the necessary drug concentration to the tumor site and prevent systemic adverse effects, the concept of administering local treatment for lung cancer has been explored.

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).

In 2010, CRI researchers Drew Pardoll, M.D., Ph.D., Susan Topalian, M.D., and colleagues completed a phase I study showing that a PD -1-specific monoclonal antibody induces frequent tumor regressions in patients with advanced melanoma, renal cancer, lung cancer, and colon cancer with very low rates of toxicity.

All those induced with skin and lung cancer contracted the diseases, but those who exercised had smaller tumors,» reports Quartz.

Lung cancer is not the only type of tumor that can induce a state promoting inappropriate clotting, though, so if heart disease is not found, a tumor search should be initiated with abdominal ultrasound.