When planning a diet -
induced obesity study, the composition of the high - fat diet deserves attention.
Not exact matches
And most research on diet and health or PTSD comes from correlational
studies, as no ethics committee will let you
induce obesity or traumetize someone for an experiment.
A
study in this issue of JCI Insight demonstrates that mice lacking the proinflammatory signaling molecule TAK1 are protected from
obesity and insulin resistance
induced by a high fat diet.
This
study, «Engineered epidermal progenitor cells can correct diet -
induced obesity and diabetes,» is the first to show that an engineered skin graft can survive long term in wild - type mice with intact immune systems.
The
study's finding that
obesity -
induced inflammation impacts the presence of taste buds «provides a possible link between
obesity and taste,» says Kathryn Medler, a taste physiologist at the University at Buffalo in New York, who was not involved with the research.
The researchers investigated 16 groups of female and male mice offspring exposed to maternal diet -
induced obesity and male hormone excess and
studied how these environmental factors affected the mice's behaviour as well as gene expression in the brain.
A new University of Iowa
study in mice shows that drug -
induced changes to the gut microbiome can cause
obesity by reducing the resting metabolic rate — the calories burned while sleeping or resting.
The
study, published online last week in the Journal of the Federation of American Societies for Experimental Biology, is the first to demonstrate that PQQ can protect offspring of obese mothers from acceleration of
obesity -
induced liver disease.
In a
study published in Diabetes on February 6, researchers identified CST's role in the recruitment and function of macrophages in the liver as well as regulation of
obesity -
induced liver inflammation and insulin resistance.
The upregulation of Il15 mRNA in skeletal muscles from IL - 15Rα — KO mice reported in the current
study could potentially contribute to the altered body composition observed in these mice (14), as HSA - IL - 15TG mice had lower adiposity and were resistant to high - fat diet —
induced obesity (34).
In the current
study, we found that while a high fat diet containing Plenish also
induced obesity, glucose intolerance and fatty liver, it did not
induce insulin resistance as did the conventional soybean oil.
During his postdoctoral training, he
studied the development of diet -
induced obesity in selectively - bred strains of Sprague - Dawley rats that either become obese or remain lean when exposed to a high - fat diet.
For example, 2013 saw
studies showing that transplanting human fecal microbiota into mice could
induce obesity and its associated metabolic phenotypes, and human data from a controlled
study suggesting the procedure could treat recurrent C. difficileinfection.
The endocannabinoid system regulates energy homeostasis through G protein — coupled cannabinoid - 1 receptors5, 6 located in the central nervous system and in various peripheral tissues, including adipose tissue, muscle, the gastrointestinal tract, and the liver.7 While peripheral cannabinoid - 1 receptor activation decreases adiponectin production in adipocytes, 8 central cannabinoid - 1 receptor activation in preclinical
studies stimulates eating, decreases muscle, and stimulates hepatic and adipose tissue lipogenic pathways in animal models of
obesity.9 In genetic and diet -
induced obesity, rimonabant, a selective cannabinoid - 1 receptor blocker, reduces overactivation of the central8, 10 and peripheral11, 12 endocannabinoid system8, 10,13 and prevents weight gain and associated metabolic disorders, thus revealing a novel strategy for the treatment of
obesity and related cardiometabolic disorders.
Studies show that exposure to PFCs is associated with smaller birth weight in newborns, elevated cholesterol, abnormal thyroid hormone levels, inflammation of the liver, weaker immune systems, kidney and testicular cancers,
obesity and even pregnancy -
induced hypertension and preeclampsia.
Studies have shown links to kidney cancer, high cholesterol,
obesity, abnormal thyroid function, pregnancy -
induced high blood pressure and low - birth - weight infants.
In a new
study in
Obesity, researchers found that diet -
induced thermogenesis (DIT)-- the number of calories burned after a meal — can be as much as 50 percent lower in the evening than in the morning.
What the animal
studies show us is that when fructose and vegetable oils are consumed together, they multiply each other's
obesity -
inducing effects.»
Studies suggest that vitamin C can, therefore, prevent stress -
induced oxidative damage to the body, reduce overall inflammation and help prevent chronic illnesses like
obesity and cardiovascular disease.