Not exact matches
Currently, she is investigating how inhibiting aldehyde dehydrogenase can kill
ovarian cancer stem
cells by
inducing necroptosis.
Growth inhibition
induced by antiprogestins RU - 38486, ORG - 31710, and CDB - 2914 in
ovarian cancer cells involves inhibition of cyclin dependent kinase 2.
Odunsi K, Qian F, Matsuzaki J, Mhawech - Fauceglia P, Andrews C, Hoffman EW, Pan L. Ritter G, Villella J, Thomas B, Rodabaugh K, Lele S, Shrikant P, Old LJ, Gnjatic S. (2007) Vaccination with an NY - ESO - 1 peptide of HLA class I / II specificities
induces integrated humoral and T
cell responses in
ovarian cancer.
A novel approach to
cancer immunotherapy — strategies designed to
induce the immune system to attack
cancer cells — may provide a new and cost - effective weapon against some of the most deadly tumors, including
ovarian cancer and mesothelioma.
In the experiments described in the paper, the MGH team confirmed that their mesothelin - targeting fusion protein binds to mesothelin on either
ovarian cancer or mesothelioma
cells, activates dendritic
cells, and enhances the
cells» processing and presentation of several different tumor antigens,
inducing a number of T -
cell - based immune responses.
Sulforaphane
induces cell cycle arrest by protecting RB - E2F - 1 complex in epithelial
ovarian cancer cells.