Sentences with phrase «induced oxidative damage»

Helps protect against light - induced oxidative damage of photoreceptors.

A combination of clove leaf oil and cinnamon leaf oil protected lipids in the skin from ultraviolet radiation - induced oxidative damage in a study published in a 2007 issue of the journal «Cutaneous and Ocular Toxicology.»

Studies suggest that vitamin C can, therefore, prevent stress - induced oxidative damage to the body, reduce overall inflammation and help prevent chronic illnesses like obesity and cardiovascular disease.

There is increasing evidence that free radical - induced oxidative damage plays a significant role in the pathogenesis of Alzheimer's disease.

Ceruloplasmin binds free copper ions and prevents free radical — induced oxidative damage.4 In a similar manner, ceruloplasmin facilitates iron loading onto its transport protein (i.e., transferrin) and prevents free ferrous (Fe +2) from participating in free radical — generating reactions.4

Age - induced oxidative damage caused deformities in the ability of key enzymes to bind to their substrate components.

This potentially cancer - inducing oxidative damage might be prevented or limited by dietary antioxidants found in fruit and vegetables.

Not exact matches

The researchers experimented with inducing oxidative stress in a human cell line culture with and without VCOP (virgin coconut oil polyphenols) to observe how VCOP positively promoted catalase, a very important enzyme in protecting the cell from oxidative damage, and glutathione (GSH), a self - recycling antioxidant produced by the liver.

Too many free radicals cause oxidative damage to healthy tissues and induces aging.

Effects of oxidative stress induced by high dosage of dietary iron ingested on intestinal damage and caecal microbiota in Chinese Yellow broilers — Z. Y. Gou — Journal of Animal Physiology and Animal Nutrition

Increased free radical induced oxidative stress plays a pivotal role in pathogenesis of many diseases including obesity, T2D and AP [7, 39 - 43] leading to macromolecular damage (DNA, protein and lipids), inflammation, ER stress and necrosis of acinar cells [44].

Despite the protection offered by the cellular environment, the integrity of DNA is continuously challenged by a variety of endogenous and exogenous agents (e.g. ultraviolet light, cigarette smoke, environmental pollution, oxidative damage, etc...) that cause DNA lesions, interfering with proper cellular functions, such as transcription, inducing premature cellular death and finally premature ageing and organs dysfunctions.

In the skin, inflammation induces oxidative stress, reducing cells» ability to defend themselves from free radical damage and promoting collagen breakdown.

Alternate - day fasting protects the rat heart against age - induced inflammation and fibrosis by inhibiting oxidative damage and NF - kB activation.

One reason might be the role of fat in inducing oxidative stress and creating free radicals, which are highly reactive atoms and molecules that damage DNA and cellular walls, ultimately killing heart muscle cells.

Lead is one of many toxic metals that cause damage by inducing oxidative stress.

Ketogenic diets have a long history of efficacy for disorders of the CNS, most notably epilepsy.46, 47 KBs are more efficient than glucose and induce less oxidative damage.47 Additionally, KBs are brought into the brain by monocarboxylate transporters — independently of glucose and insulin — so their uptake is not hindered when insulin signaling fails.51

Notably, it contributes to tumor initiation by inducing oxidative stress, DNA damage, and chromosomal instability.

Curcumin research suggests that curcumin has a protective effect against aluminum - induced damage by modulating the extent of oxidative stress.

In instances of higher turnover of cells seen with excess oxidative damage due to iodine excess and selenium deficiency, more antibodies are produced, and an immune system shift can be induced, resulting in the failure to recognize self from non-self.

Oxidative stresses induced by free radicals cause DNA damage, which, when left unrepaired, can lead to base mutation, single and double strand breaks, DNA cross-linking, and chromosomal breakage and rearrangement.

«Catuaba (Trichilia catigua) prevents against oxidative damage induced by in vitro ischemia - reperfusion in rat hippocampal slices.»

For those suffering from lead or other heavy metal poisoning, a protective diet that avoids processed foods and emphasizes the central components of a nutrient - dense and antioxidant - rich WAPF - style diet is essential (see sidebar).21 Nutritional status shapes susceptibility to lead toxicity in important ways, affecting lead's intestinal absorption; its mobilization, distribution and retention in the body; and excretion.22 Because oxidative stress is a likely mechanism explaining some of lead's toxic actions, some investigators have begun to explore whether natural antioxidants and trace minerals may help mitigate lead - induced cell damage.17 Specifically, researchers in Spain found that administration of vitamins A, B6, C and E along with zinc modulated some of the negative effects of lead exposure in rat pups, confirming the influence of nutritional factors on health outcomes following lead exposure.17 Vitamin D also should be a major component of a protective diet.

In the small intestine, the effects these drugs have been shown to produce include inhibition of cyclo - oxygenase, mitochondrial dysfunction and free radical - induced oxidative changes, all of which contribute to the mucosal damage seen.

It also reduces oxidative stress and damage, lowers cholesterol, reduces inflammatory signaling molecules, promotes cleanup and induces protective mechanisms within the brain.

Boric acid treatment was protective and led to increased resistance of DNA to oxidative damage induced by AFB1.

Natrol Sleep «N Restore is a comprehensive night time sleep aid that is packed with powerful antioxidants that can protect your body from oxidative damage induced by a hectic lifestyle.

Several candidate mechanisms of CRCI have been proposed, including inflammation and cytokine dysregulation, chemotherapy - induced epigenetic changes, blood — brain barrier disruption, hormone deficiencies, oxidative DNA damage and shortened telomere length, and genetic susceptibility.21 — 26 However, the heterogeneity and design limitations within the emerging body of evidence have led to recommendations for harmonising study methodologies and moving towards multisite, longitudinal research.3 27 Such approaches would support the demonstration of robust relationships between measurable biological processes and cognitive outcomes.