Sentences with phrase «inducing apoptosis»

In a 2013 study, researchers had found that quercetin inhibited the growth of pancreatic cancer cells by inducing apoptosis, or «cell suicide.»

It rebalances acid / alkaline in the system and may help prevent other cancers by inducing apoptosis in human skin, thyroid, gastric, liver, colon, cervical and prostate cancer cells.

Green tea reduces C - reactive protein and green tea catechins can successfully banish cancer cells, by slowing metastasis, inhibiting cell proliferation and inducing apoptosis.

They also act aggressively against cancer by preventing cancer cell proliferation, inducing apoptosis — or cancer cell «suicide» — and inhibiting the formation of new blood vessels that nourish tumor growth.

As if that were not challenge enough for a brain that is already struggling to metabolize fuel efficiently, AGEs themselves have been shown to be neurotoxic, likely by inducing apoptosis (cell death) and lipid peroxidation — a process that is especially damaging to cells whose membranes are particularly rich in PUFAs.10, 33

Chlorella has anticancer properties, preventing the growth of cancerous cells by inducing apoptosis, or cell death.

It effectively blocks cancer cell growth while inducing apoptosis, or cell death, in cancer cells.

Duntas (2015) articulates, «In susceptible individuals, iodine excess increases intra-thyroid infiltrating Th17 cells and inhibits T regulatory (Treg) cells development, while it triggers an abnormal expression of tumor necrosis factor - related apoptosis - inducing ligand (TRAIL) in thyrocytes, thus inducing apoptosis and parenchymal destruction» (31, p. 721).

To determine whether or not the damaging effects on cancer cells would affect normal cells — which are already programmed normally for apoptosis — they doused both cancerous liver cells and normal liver cells with CVE to examine the process of inducing apoptosis, which involves creating DNA damage as a precursor.

15 - deoxy - Δ12, 14 - prostaglandin J2 (15d - PGJ2), a prostaglandin derivative, has shown its anti-tumor activity by inducing apoptosis through reactive oxygen species (ROS)- mediated inactivation of v - akt, a murine thymoma viral oncogene homolog, (AKT) in cancer cells.

The group demonstrated that the AMPs directly act on the virus, rather than just inducing apoptosis or necroptosis of the infected cells as others were seen to do.

Viral vectors are known to affect the transcriptional profile from target cells, altering their behavior and sometimes inducing apoptosis [6].

We then examined whether VPA regulated immune homeostasis and ameliorated GVHD through inducing apoptosis of CD4 + T cells in vivo.

Thus, VPA did not reduce GVHD by inducing apoptosis of CD4 + effector T cells.

In patients with ALL, this leads to a sharp fall in serum levels of asparagine, hindering protein synthesis in malignant cells and inducing apoptosis, or programmed cell death.»

Rather, the group speculates that the transplanted cells secreted protective neurotrophins, proteins that promote cell survival by keeping neurons from inducing apoptosis (programmed cell death).

Goji's are reported to have anti-aging properties and show anti-tumor activities against various types of skin cancer cells by inhibiting tumor growth and inducing apoptosis.

Cucurmosin has been shown to induce apoptosis in various cancer cells tested.

As a result, the animals treated with blueberry, spinach, or spirulina were reported to have reduced ischemia / reperfusion - induced apoptosis and cerebral infraction.

So alpha - lac may induce apoptosis by directly causing the destruction of DNA from within the cell's nucleus, or it may instigate the suicide - generating caspace cascade through the mitochondria.

Certain existing chemotherapy drugs are designed to induce apoptosis, rather than «septic» cell death which is called necrosis, for this reason.

Activation of the Fas receptor then induces apoptosis in these cells.

That's how the tumor cells may be able to avoid the induced apoptosis,» says Zou.

Replication increases β - cell vulnerability to human islet amyloid polypeptide - induced apoptosis

By contrast, DN T cells are able to mediate DTH to donor alloantigens and induce apoptosis of donor - specific corneal endothelial cells.

The capacity of each cell population to induce apoptosis was tested using a 24 - hr three - color apoptosis assay.

The role of DN T cells in corneal allograft rejection was confirmed in two separate in vitro assays in which CD8 − cells were isolated from CD4 KO donors that had rejected corneal allografts and were found to induce apoptosis of donor - specific corneal cells.

miR - 34a suppresses proliferation and induces apoptosis of human lens epithelial cells by targeting E2F3.

IG20 (MADD splice variant - 5), a proapoptotic protein, interacts with DR4 / DR5 and enhances TRAIL - induced apoptosis by increasing recruitment of FADD and caspase - 8 to the DISC.

Live fluorescence and transmission - through - dye microscopic study of actinomycin D - induced apoptosis and apoptotic volume decrease.

Expression of sulfotransferase isoform 1A1 (SULT1A1) in breast cancer cells significantly increases 4 - hydroxytamoxifen - induced apoptosis.

In addition, consistent with past studies, AAV2 - infected cancer cells produced more Ki - 67, an immunity system activating protein and c - Myc, a protein that helps both to increase cell growth and induce apoptosis.

p38 MAP kinase mediates arsenite - induced apoptosis through FOXO3a activation and induction of Bim transcription.

MicroRNA - 15a inhibition protects against hypoxia / reoxygenation - induced apoptosis of cardiomyocytes by targeting mothers against decapentaplegic homolog 7.

Synergistic effect of radachlorin mediated photodynamic therapy on propolis induced apoptosis in AMC - HN - 4 cell lines via caspase dependent pathway.

Additional studies are attempting to determine if the transgene expression of various anti-apoptotic genes can protect T cells from tumor - induced apoptosis.

The SUMO ligase PIAS1 regulates UV - induced apoptosis by recruiting Daxx to SUMOylated foci % U http://jcs.biologists.org/content/early/2012/09/07/jcs.110825.short.

Matrix metalloproteinase - 2 contributes to tumor necrosis factor alpha induced apoptosis in cultured rat cardiac myocytes.

GCP, a genistein - rich compound, inhibits proliferation and induces apoptosis in lymphoma cell lines.

Protein kinase Cα and ζ differentially regulate death - inducing signaling complex formation in cigarette smoke extract - induced apoptosis.

In the bone marrow microenvironment, CLL cells are protected from spontaneous or drug - induced apoptosis, resulting in resistance to conventional chemotherapy.

Activation of the extrinsic caspase pathway in cultured cortical neurons requires p53 - mediated down - regulation of the X-linked inhibitor of apoptosis protein to induce apoptosis.

MEK kinase 1, a substrate for DEVD - directed caspases, is involved in genotoxin - induced apoptosis.

The synthetic peptide PFWT disrupts AF4 — AF9 protein complexes and induces apoptosis in t (4; 11) leukemia cells.

Dominant negative mutant forms of the cAMP response element binding protein induce apoptosis and decrease the anti-apoptotic action of growth factors in human islets.

Targeting of the c - Abl tyrosine kinase to mitochondria in endoplasmic reticulum stress - induced apoptosis.

Phosphorylation of Merkel cell polyomavirus large tumor antigen at serine 816 by ATM kinase induces apoptosis in host cells.

The role of enoyl - CoA hydratase short chain 1 and peroxiredoxin 3 in PP2 - induced apoptosis in human breast cancer MCF - 7 cells.

Dual Blockade of PKA and NF — $ ąppa $ B Inhibits H2 Relaxin - Mediated Castrate - Resistant Growth of Prostate Cancer Sublines and Induces Apoptosis.

Injections of iPSC - EPCs did not however have significant effect on tumor growth or on overall survival, but transducing cells with a baculovirus expressing CD40L, a member of the TNF gene family which can induce apoptosis [6, 7], and injection into the breast cancer lung metastasis, increased levels of pro-apoptotic cytokines in lung tissues, indicating the induction of apoptosis by CD40L carried by the EPCs (See figure).