HAND2 is active in the healthy endometrium (the tissue lining the uterus) where it antagonizes the growth -
inducing effects of estrogen.
Results of experiments in multiple laboratories over the last 20 years have shown that a large part of the cancer -
inducing effect of estrogen involves the formation of agonistic metabolites of estrogen, especially 16 - alpha - hydroxyestrone.
Not exact matches
Alfalfa sprouts are also a good dietary source
of phytoestrogens, which
induce similar
effects to true
estrogens.
Natural progesterone, but not medroxyprogesterone acetate, enhances the beneficial
effect of estrogen on exercise -
induced myocardial ischemia in postmenopausal women.