Sentences with phrase «inducing eye field»
One interpretation of this result is that EFTFs induce an eye field - like fate in pluripotent cells.
http://journals.plos.org/ Not exact matches
In the new work, published June 10 in the journal Scientific Reports, Zhao, Reid and colleagues used a highly sensitive probe to measure electrical fields in the corneas of isolated eyes from three different lab mouse models with different types of diabetes: genetic, drug - induced and in mice fed a high - fat diet.
This interpretation predicts that transcripts expressed in the eye field should also be induced in EFTF - expressing pluripotent cells.
These observations prompted us to replace the eye field with EFTF - expressing pluripotent cells to ask if the induced retinal cells could generate a normal eye and if induced retinal ganglion cells would extend axons to and synapse with their normal tectal targets.
When the endogenous eye field was replaced with induced retinal cells, they formed eyes that were molecularly, anatomically, and electrophysiologically similar to normal eyes.