Sentences with phrase «infect cells in a laboratory»

After that, the study subjects were quarantined for six days and given cold - virus - containing nose drops at a dose about 125 times the amount that it takes to infect cells in a laboratory.

Not exact matches

«The best explanation for what we are seeing is that frequently, after exposure to HIV, a few cells in the genital tract are infected, without establishment of a systemic infection,» says senior investigator Eric Hunter, PhD, professor of pathology and laboratory medicine at Emory University School of Medicine, Emory Vaccine Center, and Yerkes National Primate Research Center.

The virus, redesigned using sophisticated protein engineering techniques, works: With its shield and its adapter, these viral gene shuttles efficiently infected tumor cells in laboratory animals.

The mutated, drug resistant H7N9 virus, however, was still able to infect cultured human cells and spread between laboratory animals as efficiently as nonmutated strains, researchers report December 10 in Nature Communications.

By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the virus.

In conjunction with the laboratory of Matthew J. Evans, PhD, from the Department of Microbiology at Icahn School of Medicine at Mount Sinai, investigators demonstrated the functionality of the liver cells generated from the progenitors, as the liver cells can be infected by the hepatitis C virus, a property restricted to liver cells exclusively.

Building on the newly - published pilot study, the team will conduct experiments using a windtunnel which measures the behaviour of mosquitoes towards odours and electrodes which track the response of individual odour - detecting cells from within the antenna of the mosquito in specially - designed secure laboratories at the School to measure the responses of malaria - infected Anopheles gambiae s.s. females to human odours.

At the Galveston National Laboratory, which houses a biosafety level 4 lab, researchers shut down experiments, euthanized infected animals, put pathogens in cold storage, and autoclaved cell cultures.

In laboratory studies reported in the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cellIn laboratory studies reported in the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cellin the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cells.

Their approach is to combine the study of cells isolated from TB - infected patients with micro-engineering in 3D in the laboratory to investigate how TB damages the lungs.

«There are two types of T cells — CD8 and CD4 — which battle invading pathogens,» explains lead author Pablo Penaloza - MacMaster, PhD, a postdoctoral fellow in the Barouch laboratory and Instructor of Medicine at HMS «The CD8 T cells take the lead in eliminating virally infected cells while the CD4 «helper» T cells function indirectly, serving to bolster the responses of both CD8 T cells and antibody - producing B cells.»

The laboratory experiments also showed that the amino acid combination in the CDV - H protein typically found in domestic dog strains (519R / 549Y) was particularly good at invading cells with domestic dog receptors but far less efficient at entering cells with non-canid receptors, effectively making domestic dog strains less able to infect lions and spotted hyenas if they are exposed to them.

His laboratory and their collaborators have also identified human amyloid fibrils in semen that enhance the ability of HIV to infect new cells — a discovery that one day could help stem the global spread of this deadly pathogen.

Recent studies from the laboratory revealed that primary transcripts of ebv - miR - BART6 (pri - miR - BART6) are edited by ADAR1 in latently EBV - infected cells.

While evidence obtained in our and other laboratories strongly suggests that H. pylori triggers a transcriptional response, epigenetic alterations and DNA damage in infected cells, most of the data supporting these findings rest on fragmentary analyses of clinical samples and cells infected in vitro.

«We systematically screened over 50 methyltransferases to determine which ones regulate latency in infected T cells,» said Daniela Boehm, postdoctoral scholar in the Ott laboratory and first author of the study.

In the new study, however, the researchers used blood samples of monkeys with Zika virus and Zika - infected laboratory cells.

On the contrary, recent evidence indicates that XMRV is a contaminant originating from the recombination of two mouse endogenous retroviruses during passaging of a prostate tumor xenograft (CWR22) in mice, generating laboratory - derived cell lines that are XMRV - infected.

We reasoned that contamination from XMRV - infected LNCaP cells was more likely given that the laboratory at the Cleveland Clinic performing the nucleic acid extractions in 2004 was simultaneously working with LNCaP and had only worked with 22Rv1 more than 2 years prior.

The LNCaP cell line, in turn, had been likely infected with XMRV from 22Rv1 cells in the same laboratory in which 22Rv1 cells were previously used, or in another laboratory at the Cleveland Clinic that was working with both cell lines and had initially provided the LNCaP cells for analysis.

The study concludes that infectious virions constitute only a small fraction of a typical HIV - 1 preparation and that, in a laboratory setting, all of the infectious virions can bind to red blood cells and other non-permissive cells (i.e., cells that can not be infected).