Sentences with phrase «infect cells of the body»

When pathogens infect the cells of the body, the infection sets off a chain reaction involving the immune system that changes the activity, or expression, of hundreds of genes.

Not exact matches

So many researchers believe ARVs are doing all they can do and they focus on ridding the body of the «reservoirs» of latently infected cells, which are long - lived.
Malaria parasites, which are transmitted through the bite of an infected mosquito, cause the most destruction during the part of their life cycle when they dwell in red blood cells circulating through the body.
By studying infected cells grown in a laboratory, the team found that a large number of CMV's genes help it hide from the immune system by allowing it to destroy many of the proteins produced by the body during virus infection and preventing them from activating immune cells to destroy the virus.
Although changes in treatment methodology still have to be studied, Dr. Cripe believes it may be that the timing of various treatments is what matters, and that perhaps initially suppressing immunity could allow the virus to infect a large number of tumor cells before relieving the immunosuppression to allow the body's own T cells to fight off the tumor.
The new study revives suspicions that adenoviruses cause an immune «own goal», priming people's immune systems to produce CD4 cells — the very cells that HIV prefers to infect — and, worse still, to direct those cells to the parts of the body that are most vulnerable to the virus during sex.
However, despite the success of HAART in effectively reducing the burden of HIV, scientists believe reservoirs of latently infected cells persist in the body, preventing the possibility of a permanent cure.
«When a person is infected with HIV, the virus infects immune cells and knocks out the body's interferon production; the first line of defence in our bodies.
«The imaging system, developed by Dr. Young while at the University of Pittsburgh, pinpoints the spatial and temporal location of HIV -1-infected cells in the body, allowing us to observe HIV - 1 replication in real - time and to essentially see HIV - 1 reservoirs in latently infected cells and tissues,» Dr. Khalili explained.
Researchers have been seeking a way to improve the body's ability to combat the virus by engineering blood - forming stem cells to specifically target and kill HIV - infected cells for the life of the individual.
Eliminating infected cells rids the body of the infection.
If the T cells judge the pieces to be foreign or in need of removal, they reproduce, forming an army of clones that hunt down infected and rogue cells in the body.
In a letter published in the cancer journal Annals of Oncology, researchers led by Professor Jean - Philippe Spano, head of the medical oncology department at Pitie - Salpetriere Hospital AP - HP in Paris, France, report that while treating an HIV - infected lung cancer patient with the cancer drug nivolumab, they observed a «drastic and persistent decrease» in the reservoirs of cells in the body where the human immunodeficiency virus (HIV) is able to hide away from attack by anti-retroviral therapy.
CD74 is broken into products that fit into the groove of cell surface immune response proteins as part of the chain of events that activates T cells — immune cells that normally attack infected (or damaged) cells in the body.
The bacterium that causes tuberculosis, Mycobacterium tuberculosis, or Mtb, previously was thought to infect the body only through inhalation and subsequent infection of cells in the lungs.
Vaccines work by exposing the body to the disease - causing agent or a fragment of it, which primes the immune system to produce a flood of antibodies that stick to the infecting organism and block it from entering cells.
Despite initial hopes that the drugs might eradicate the virus from the body, it soon became clear that no one was cured because of stubborn reservoirs of cells infected with latent virus.
That gene, HLA - B * 5701, codes for a protein on immune cells that plays a central role in clearing the body of HIV - infected cells.
And the field now knows that a cure is indeed possible because of an unusual stem cell transplant in one HIV - infected person with leukemia who no longer has any detectable virus in his body.
Koyuncu discovered this when she infected isolated axons with a small number of virus particles, which would normally travel to the cell bodies and be silenced, while simultaneously exposing the cell bodies to a large number of inactivated virus particles that have been dosed with ultraviolet radiation (UV).
These findings suggest an important role for calcium ion signaling in regulating extrusion and could help improve understanding of how the bacterium leaves an infected cell and spreads within the body of an infected person of animal.
A study from Dr. Dusty Miller's laboratory indicates that Jaagsiekte sheep retrovirus (JSRV) infects both sheep and human cells cultured outside the body and does so by attaching to a receptor on the surface of lung cells.
Mock - infected control (A); Severe hemorrhage and regression of ovarian follicles (B); Spleens from mock - infected control (left) and enlarged spleens from the infected ducks (C); HE - stained ovary section showing hemorrhage and follicle rupture with red stained bodies (D); HE - stained brain section revealing lymphocytes and mononuclear cell infiltration under cranial arachnoid (E) and focal gliosis (arrow)(F).
To eliminate HIV latency, scientists are exploring a «shock and kill» strategy that would use a combination of drugs to wake up the dormant virus, then act with the body's own immune system to eliminate the virus and kill infected cells.
Natural Killer cells patrol the body and detect characteristic alterations on the surface of cancer cells or virus - infected cells.
Strong evidence however shows that this doesn't mean that cells are actually «destroyed» or «lost», but instead they are moved to other parts of the body such as the lungs which have more of a chance of becoming infected.
It triggers the production of white blood cells, helping the body to reject virally infected cells and maintain optimal health.
According to the Federation of American Societies for Experimental Biology, hyperthermia, or the exposure of the body to high temperatures, gives these cells the ability to destroy virus - infected cells and tumor cells.
The herpes virus can also infect the cells present in the body and it can not be reproduced without the help of the cell.
The once - preposterous notion of invisible creatures inhabiting our world opened the door to understanding how germs infect the body, how cells replicate, and how life itself begins.
The primary result of a Babesia infection is anemia as the immune system destroys infected red blood cells, but Babesia can have other effects throughout the body as well.
It attacks white blood cells in the body and literally destroys the lining of the GI tract, allowing bacteria to infect the bloodstream (a serious condition called septicemia).
With the assistance of the antibodies that are supposed to protect the cat, white blood cells are infected with virus, and these cells then transport the virus throughout the cat's body.
Distemper inclusion bodies are clumps of virus that are visible under the microscope within infected cells.
DISTEMPER INCLUSION BODIES — «Distemper inclusion bodies» are actual clumps of virus that are visible under the microscope within infected BODIES — «Distemper inclusion bodies» are actual clumps of virus that are visible under the microscope within infected bodies» are actual clumps of virus that are visible under the microscope within infected cells.
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