Sentences with phrase «infected cells in tissue»

The immunoperoxidase test detects virus - infected cells in the tissue, but a biopsy of affected tissue is necessary for evaluation.

The immunoperoxidase test can diagnose FIP more accurately than traditional histopathologic examination because it detects virus - infected cells in the tissue.

An international team of scientists, led by Monash Biomedicine Discovery Institute researcher Dr Di Yu, and Dr Axel Kallies from the Walter and Eliza Hall Institute, have discovered that killer T cells, a specialised type of white blood cells, can find these «hidden» infected cells in tissue and destroy them.

Not exact matches

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

To address this gap in knowledge, Mirabello and Schiffman teamed up with co-senior author Robert Burk of Albert Einstein College of Medicine to sequence the whole genomes of 5,570 HPV16 - infected cell and tissue samples from women around the world and to identify associations between HPV16 genetic variants and the risk of cervical precancer and cancer.

Researchers also studied the brain tissue of the infected mice under a microscope and found that the memory problems tracked with changes in nerve cells.

«The fundamental «killing units» of CD4 T cells in lymphoid tissues are other infected cells, not the free virus,» says co-first author Gilad Doitsh, PhD, a staff research investigator at the Gladstone Institute of Virology and Immunology.

In a new study, researchers demonstrate for the first time that recovery from bacterial pneumonia changes the tissue that was infected, seeding the lungs with immune cells called resident memory T (TRM) cells.

Following a single treatment with CRISPR / Cas9, viral fragments were successfully excised from latently infected human cells embedded in mouse tissues and organs.

«The imaging system, developed by Dr. Young while at the University of Pittsburgh, pinpoints the spatial and temporal location of HIV -1-infected cells in the body, allowing us to observe HIV - 1 replication in real - time and to essentially see HIV - 1 reservoirs in latently infected cells and tissues,» Dr. Khalili explained.

Using a powerful imaging technique that allowed the scientists to track the presence and movement of parasites in living tissues, the researchers found that Toxoplasma infects the brain's endothelial cells, which line blood vessels, reproduces inside of them, and then moves on to invade the central nervous system.

Zika virus can persist in cerebrospinal fluid (CSF), lymph nodes and colorectal tissue of infected rhesus monkeys for weeks after the virus has been cleared from blood, urine and mucosal secretions, according to a study published online in Cell.

Then, by placing surface proteins of each HCV virus onto these pseudoviruses, the researchers were able to efficiently infect human cells with the HCV strains in tissue culture.

Not only does it reveal details on how the virus quickly infects immune cells in the gut, using them as virus - producing factories, but it also highlights where the virus «hides out» deep within the intestinal tissue.

VIRUS VICTORY Zika virus (green) infects and kills stem cells (red) in human glioblastoma tissue, without infecting healthy brain cells.

They observed similar results in ART - controlled, HIV - infected patients who had undergone elective abdominal surgery: their SVF samples are positive for HIV DNA, and the researchers could show the presence of infected and virus - producing cells within the patients» adipose tissue and more specifically among adipose CD4 + T cells.

Another, previously unknown gene — when the investigators worked out its protein's structure and studied it in tissue culture — proved to do just the opposite: The protein helped the schizont leave the infected blood cell.

The team will also be looking to identify which molecule L - selectin binds to in virus infected tissues that allows killer T cells to be directed there.

«We were interested in understanding how cells commonly found in mucosal tissues affect the ability of HIV to infect immune cells,» explained Nadia Roan, PhD, a visiting investigator at Gladstone and assistant professor at UCSF who is the senior author of the study.

A paper published today in the journal Nature has reported that male mice infected with a mouse - adapted strain of Zika virus can experience tissue injury associated with decreased testis size and reduced levels of two sex hormones and of sperm cells in the seminal fluid.

«There are positive signs that the edited cells do end up in tissues that harbour infected white blood cells carrying dormant viruses, known as reservoirs, which is where they would be most useful.

Presence of CD8 + T cells in the ectocervical mucosa correlates with genital viral shedding in HIV - infected women despite a low prevalence of HIV RNA - expressing cells in the tissue.

To characterize the isolate that replicated in HeLa cells, a 166 - bp RNA sequence containing the variable region C of the envelope (Env) surface protein was PCR - amplified from infected HeLa cell tissue culture supernatants.

This is associated with a relative reduction in cytotoxic T - cell activity and a reduced capacity to destroy infected host cells and clear the virus from infected lung tissue.

But even with treatment, the virus remains dormant within a small percentage of infected CD4 cells — and perhaps even within other types of cells — in a variety of tissues.

(C) Degree of branching and number of mammary epithelial cell layers in the mammary tissue formed by mammary cells infected with miR - 150.

The result is an intense inflammatory reaction in the tissues where the virus - infected cells reside, which causes damage to multiple systems at once and ultimately leads to death.

An intense inflammatory reaction occurs around vessels in the tissues where these infected cells locate, often in the abdomen, kidney, or brain.