Sentences with phrase «infected macrophages»

Takano T, Hohdatsu T, Toda A, Tanabe M, Koyama H. 2007a TNF - alpha, produced by feline infectious peritonitis virus (FIPV)- infected macrophages, upregulates expression of type II FIPV receptor feline aminopeptidase N in feline macrophages.

HIV - infected macrophages can survive in many tissues and accumulate intracellular stocks of infectious HIV.

A new Infection and Immunity report describes how infected macrophages send signals to uninfected macrophages: via exosomes.

peritoneal macrophages derived from A / J mice are susceptible to Legionella pneumophilia infection; infected macrophages show a 10-fold increase in bacterial burden after 1 day of infection compared to resistant controls (C57BL / 6J)

This cell death is induced by many rough attenuated Brucella strains, including Brucella cattle vaccine strain RB51, B. abortus wboA mutant VTRA1, and B. suis wboA mutant VTRS1.This cell death is prevented by wild type virulent Brucella in infected macrophages, but not in dendritic cells.

«The fact that HIV - infected macrophages can persist means that any possible therapeutic intervention to eradicate HIV might have to target two very different types of cells.»

Interestingly, virulent Brucella inhibits such cell death in infected macrophages (He et al, 2006) but not in dendritic cells (Li & He, 2012).

These agents could specifically kill the infected macrophages, leaving uninfected macrophages untouched — exactly what you would want to happen if you were treating an infected person,» Dr Vince said.

The study's researchers infected macrophages, a type of human white blood cell, with a highly virulent strain of tuberculosis.

They hint that viruses adapted to infecting macrophages and monocytes are most likely to be passed to the woman during sex.

Dr Vince said that soon after infecting a macrophage, Legionella bacteria alter the composition of proteins within their host cell to prevent the host from detecting the infection.

Not exact matches

«HIV - infected young males have higher rates of bone loss than females: Study suggests macrophage activation as possible reason for differential bone loss in adolescent males.»

The researchers found that HIV spiked into semen was more successful than the virus alone at infecting T cells and macrophages (immune system cells that are believed to be the infection's initial targets in the body).

They are recruited to sites of injury or infection and there turn into macrophages (literally «large eaters») that ingest pathogens, infected cells, or cellular debris.

The resulting disease - causing (virulent) parasite forms, called amastigotes, infect and multiply in immune cells called macrophages at the bite site and after dissemination of the infection to secondary sites.

HIV - 1 infects and kills immune system cells, including T cells and macrophages that were used in the study.

During a bacterial infection, monocytes penetrate the infected tissue where they differentiate / change into macrophages.

Two - dimensional liquid chromatography - tandem mass spectrometry coupled with isobaric tags for relative and absolute quantification (iTRAQ) labeling approach revealed first proteome profiles of pulmonary alveolar macrophages infected with porcine reproductive and respiratory syndrome virus.

Treating the infected mice with vancomycin eliminated MRSA from mice infected with the free bacteria, but MRSA residing within macrophages were able to survive and colonize both the kidney and the brain.

Although this study was done in mice, the same mechanisms were found in human macrophages infected with TB.

HeLa cells were infected with supernatant from the murine macrophage cell line RAW264.7 (ATCC, Manassas, VI) known to express polytropic and ecotropic MuLV (PMLV and EMLV, respectively).

She is currently focusing on M. tuberculosis drug screening in mammalian macrophages infected with the bacteria.

However in the case of HIV, macrophages are used by the virus, which efficiently infects them and makes them produce new virions.

The macrophages swallow the bacterial cells and then release powerful anti-bacterials that prevent bacteria from further dividing and infecting host cells.

By infecting susceptible mouse macrophages with S. Typhimurium and using global proteomics to analyze the proteins at various time points following infection, researchers identified 1,006 macrophage proteins.

Using primary murine bone marrow derived macrophages or human monocyte derived dendritic cells, infected with live or attenuated Chlamydia trachomatis we report that the live organism activates both canonical and non-canonical inflammasomes, but only canonical inflammasomes controlled IL - 1β processing which preceded pyroptosis.

Under the guidance of a world - renowned cancer biologist, Robert Weinberg, Ph.D., Lu is focusing on how metastatic breast cancer cells interact with a subset of immune cells called macrophages, which normally are capable of engulfing — literally eating — infected, damaged, or cancerous cells.

For quantification of phagocytosis, alveolar macrophages were infected at an MOI of 20 for 1 h, then media was removed, extracellular bacteria were killed with gentamycin (200 μg / ml for 10 min at 37 C), and macrophages were lysed with 0.2 % triton X-100 (10 min at room temperature).

The virus is not fully understood — largely because the virus mutates and has the ability to attack and breed in specified white blood cells, specifically macrophages — but what is known is that cats become infected when they ingest or inhale the virus.

Takano T, Azuma N, Satoh M, Toda A, Hashida Y, Satoh R, Hohdatsu T. 2009 Neutrophil survival factors (TNF - alpha, GM - CSF, and G - CSF) produced by macrophages in cats infected with feline infectious peritonitis virus contribute to the pathogenesis of granulomatous lesions.

8 to 14 days later spread to epithelial and CNS tissues occurs through infected lymphocytes and macrophages.